9H4D
 
 | | Crystal structure of IL-17A in complex with compound 18 | | 分子名称: | (E)-N-[(1S)-1-[4,4-bis(fluoranyl)cyclohexyl]-2-oxidanylidene-2-[[5-[(2-oxidanylidene-3H-benzimidazol-1-yl)methyl]-1,3-thiazol-2-yl]amino]ethyl]-3-cyclopropyl-2-fluoranyl-prop-2-enamide, Interleukin-17A | | 著者 | Rondeau, J.M, Lehmann, S, Scheufler, C. | | 登録日 | 2024-10-18 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-04-16 | | 実験手法 | X-RAY DIFFRACTION (2.117 Å) | | 主引用文献 | Thiazole-Based IL-17 Inhibitors Discovered by Scaffold Morphing.
Chemmedchem, 20, 2025
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9H4O
 | | Crystal structure of IL-17A in complex with compound 11 | | 分子名称: | (E)-N-[(1S)-1-[4,4-bis(fluoranyl)cyclohexyl]-2-oxidanylidene-2-[[5-[[(4S)-2-oxidanylidene-4-(trifluoromethyl)imidazolidin-1-yl]methyl]-1,3-thiazol-2-yl]amino]ethyl]-3-cyclopropyl-2-fluoranyl-prop-2-enamide, Interleukin-17A, SULFATE ION | | 著者 | Rondeau, J.M, Lehmann, S, Scheufler, C. | | 登録日 | 2024-10-21 | | 公開日 | 2025-01-22 | | 最終更新日 | 2025-04-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Thiazole-Based IL-17 Inhibitors Discovered by Scaffold Morphing.
Chemmedchem, 20, 2025
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