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PDB: 153 results

2C8W
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BU of 2c8w by Molmil
thrombin inhibitors
Descriptor: (2S,3R)-N-[5-CHLORO-2-(2,3-DIHYDRO-1H-TETRAZOL-1-YL)BENZYL]-3-HYDROXY-4-{[(4-METHOXYPHENYL)SULFONYL]AMINO}-1-PHENYLBUTA N-2-AMINIUM, HIRUDIN VARIANT-2, SODIUM ION, ...
Authors:Howard, N, Abell, C, Blakemore, W, Carr, R, Chessari, G, Congreve, M, Howard, S, Jhoti, H, Murray, C.W, Seavers, L.C.A, van Montfort, R.L.M.
Deposit date:2005-12-08
Release date:2006-07-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors
J.Med.Chem., 49, 2006
2C8Y
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BU of 2c8y by Molmil
thrombin inhibitors
Descriptor: DIMETHYL SULFOXIDE, HIRUDIN VARIANT-2, N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDE, ...
Authors:Howard, N, Abell, C, Blakemore, W, Carr, R, Chessari, G, Congreve, M, Howard, S, Jhoti, H, Murray, C.W, Seavers, L.C.A, van Montfort, R.L.M.
Deposit date:2005-12-08
Release date:2006-07-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors
J.Med.Chem., 49, 2006
6HGT
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BU of 6hgt by Molmil
Crystal structure of human KDM4A complexed with co-substrate analog NOG and histone H3 peptide with K9R mutation
Descriptor: Histone H3.3, Lysine-specific demethylase 4A, N-OXALYLGLYCINE, ...
Authors:Maw, J, Le Bihan, Y.V, van Montfort, R.L.M.
Deposit date:2018-08-23
Release date:2019-09-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structure-based design of selective, histone substrate-based inhibitors of histone lysine demethylases 4 (KDM4) subfamily
To be published

222036

건을2024-07-03부터공개중

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