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PDB: 177 results

2WMW
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BU of 2wmw by Molmil
Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
Descriptor: 1-[(2S)-4-(5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL]METHANAMINE, SERINE/THREONINE-PROTEIN KINASE CHK1
Authors:Matthews, T.P, Klair, S, Burns, S, Boxall, K, Cherry, M, Fisher, M, Westwood, I.M, Walton, M.I, McHardy, T, Cheung, K.-M.J, Van Montfort, R, Williams, D, Aherne, G.W, Garrett, M.D, Reader, J, Collins, I.
Deposit date:2009-07-03
Release date:2009-07-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Identification of Inhibitors of Checkpoint Kinase 1 Through Template Screening.
J.Med.Chem., 52, 2009
6HGT
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BU of 6hgt by Molmil
Crystal structure of human KDM4A complexed with co-substrate analog NOG and histone H3 peptide with K9R mutation
Descriptor: Histone H3.3, Lysine-specific demethylase 4A, N-OXALYLGLYCINE, ...
Authors:Maw, J, Le Bihan, Y.V, van Montfort, R.L.M.
Deposit date:2018-08-23
Release date:2019-09-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structure-based design of selective, histone substrate-based inhibitors of histone lysine demethylases 4 (KDM4) subfamily
To be published

220472

數據於2024-05-29公開中

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