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PDB: 101 件
8AST
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The Crystal structure of short F46Y agroavidin - apo
分子名称: Agroavidin
著者Livnah, O, Bana, J.
登録日2022-08-21
公開日2023-04-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Self-assembly of a dimeric avidin into unique higher-order oligomers.
Febs J., 290, 2023
8ASS
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The Crystal structure of F46Y mutant of the agroavidin-biotin complex
分子名称: Agroavidin, BIOTIN
著者Livnah, O, Bana, J.
登録日2022-08-21
公開日2023-04-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Self-assembly of a dimeric avidin into unique higher-order oligomers.
Febs J., 290, 2023
6QTY
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Non-phosphorylated human CLK1 in complex with an indole inhibitor to 1.65 Ang
分子名称: Dual specificity protein kinase CLK1, ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
著者Livnah, O, Domovich, Y.
登録日2019-02-26
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Expression, purification and crystallization of CLK1 kinase - A potential target for antiviral therapy.
Protein Expr.Purif., 176, 2020
6QYX
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p38(alpha) MAP kinase with the activation loop of ERK2
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Livnah, O, Eitan-Wexler, M, Vinograd, N.
登録日2019-03-10
公開日2020-04-01
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop.
J.Biol.Chem., 295, 2020
7P0O
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mitoNEET bound to M1 molecule
分子名称: 2-benzamido-4-[(2~{R})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, 2-benzamido-4-[(2~{S})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, CDGSH iron-sulfur domain-containing protein 1, ...
著者Livnah, O, Eisenberg-Domovich, Y, Marjault, H.B, Nechushtai, R.
登録日2021-06-30
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.
Commun Biol, 5, 2022
7P0P
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NAF-1 bound to M1 molecule
分子名称: 2-benzamido-4-[(2~{R})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER
著者Livnah, O, Eisenberg-Domovich, Y, Marjault, H.B, Nechushtai, R.
登録日2021-06-30
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.
Commun Biol, 5, 2022
4Z2P
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Crystal structure of short hoefavidin-hoef-peptide(L9F) complex
分子名称: Avidin family, Hoef-peptide (L9F)
著者Livnah, O, Avraham, O.
登録日2015-03-30
公開日2015-07-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail.
J.Struct.Biol., 191, 2015
4Z27
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Crystal structure of apo short hoefavidin
分子名称: Avidin family
著者Livnah, O, Avraham, O.
登録日2015-03-29
公開日2015-08-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail.
J.Struct.Biol., 191, 2015
4Z2V
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Crystal structure of short hoefavidin-hoef-peptide complex
分子名称: Avidin family, Hoef-peptide
著者Livnah, O, Avraham, O.
登録日2015-03-30
公開日2015-07-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail.
J.Struct.Biol., 191, 2015
4Z2O
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High resolution crystal structure of short hoefavidin-hoef-peptide complex
分子名称: Avidin family, Hoef-peptide
著者Livnah, O, Avraham, O.
登録日2015-03-30
公開日2015-07-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail.
J.Struct.Biol., 191, 2015
4Z28
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Crystal structure of short hoefavidin biotin complex
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Avidin family, BIOTIN
著者Livnah, O, Avraham, O.
登録日2015-03-29
公開日2015-07-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail.
J.Struct.Biol., 191, 2015
4Z6J
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Crystal structure of apo intact hoefavidin
分子名称: Avidin family
著者Livnah, O, Avraham, O.
登録日2015-04-05
公開日2015-07-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail.
J.Struct.Biol., 191, 2015
2AVI
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THREE-DIMENSIONAL STRUCTURES OF AVIDIN AND THE AVIDIN-BIOTIN COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AVIDIN, BIOTIN
著者Livnah, O, Sussman, J.
登録日1993-04-23
公開日1993-07-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Three-dimensional structures of avidin and the avidin-biotin complex.
Proc.Natl.Acad.Sci.USA, 90, 1993
2OF8
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Crystal structure of AVR4 (D39A/C122S)-BNA complex
分子名称: 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Avidin-related protein 4/5, FORMIC ACID
著者Livnah, O, Hayouka, R, Eisenberg-Domovich, Y.
登録日2007-01-03
公開日2007-12-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.
Acta Crystallogr.,Sect.D, 64, 2008
2OF9
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Crystal structure of apo AVR4 (D39A/C122S)
分子名称: Avidin-related protein 4/5, FORMIC ACID
著者Livnah, O, Hayouka, R, Eisenberg-Domovich, Y.
登録日2007-01-03
公開日2007-12-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.
Acta Crystallogr.,Sect.D, 64, 2008
7OA0
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Crystal structure of di-phosphorylated human CLK1 in complex with 5-(6,7-dichloro-1H-indol-3-yl)pyrimidin-4-amine
分子名称: 5-[6,7-bis(chloranyl)-1-methyl-indol-3-yl]pyrimidin-4-amine, Dual specificity protein kinase CLK1
著者Livnah, O, Domovich, Y, Bracher, F, Aiger, C.
登録日2021-04-18
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Development of novel CLK1 inhibitors as potential drugs for treatment of Chikungunya virus infections
To Be Published
7O9Y
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Crystal structure of di-phosphorylated human CLK1 in complex with 4-(1H-indol-3-yl)pyrimidin-2-amine
分子名称: 4-(1~{H}-indol-3-yl)pyrimidin-2-amine, Dual specificity protein kinase CLK1
著者Livnah, O, Domovich, Y, Bracher, F, Aiger, C.
登録日2021-04-18
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Development of novel CLK1 inhibitors as potential drugs for treatment of Chikungunya virus infections
To Be Published
4S2Z
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BU of 4s2z by Molmil
ERK2 Intrinsically active mutant R65S
分子名称: Mitogen-activated protein kinase 1
著者Livnah, O, Karamansha, Y.
登録日2015-01-25
公開日2016-01-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Multiple mechanisms render Erk proteins MEK-independent
To be Published
4S34
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ERK2 (I84A) in complex with AMP-PNP
分子名称: MAGNESIUM ION, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Livnah, O, Karamansha, Y, Tzarum, N.
登録日2015-01-26
公開日2016-01-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Multiple mechanisms render Erk proteins MEK-independent
To be Published
4S32
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Crystal structure of ERK2 AMP-PNP complex
分子名称: MAGNESIUM ION, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Livnah, O, Karamansha, Y, Tzarum, N.
登録日2015-01-26
公開日2016-01-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Crystal structure of ERK2 AMP-PNP complex
To be Published
2OFA
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BU of 2ofa by Molmil
Crystal structure of apo AVR4 (R112L,C122S)
分子名称: Avidin-related protein 4/5, FORMIC ACID
著者Livnah, O, Hayouka, R, Eisenberg-Domovich, Y.
登録日2007-01-03
公開日2007-12-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.
Acta Crystallogr.,Sect.D, 64, 2008
1LCW
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BU of 1lcw by Molmil
streptavidin-homobiotin complex
分子名称: HOMOBIOTIN, Streptavidin
著者Livnah, O, Pazy, Y, Bayer, E.A, Wilchek, M.
登録日2002-04-07
公開日2002-11-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin
J.Biol.Chem., 277, 2002
4S30
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ERK2 intrinsically active mutant (I84A)
分子名称: Mitogen-activated protein kinase 1
著者Livnah, O, Karamansha, Y.
登録日2015-01-26
公開日2016-01-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Multiple mechanisms render Erk proteins MEK-independent
To be Published
4S31
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Crystal structure of mitogen-activated protein kinase 1 wtERK2 at 1.45A
分子名称: Mitogen-activated protein kinase 1
著者Livnah, O, Karamansha, Y.
登録日2015-01-26
公開日2016-01-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Multiple mechanisms render Erk proteins MEK-independent
To be Published
4S33
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ERK2 R65S mutant complexed with AMP-PNP
分子名称: MAGNESIUM ION, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Livnah, O, Karamansha, Y, Tzarum, N.
登録日2015-01-26
公開日2016-01-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Multiple mechanisms render Erk proteins MEK-independent
To be Published

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件を2024-07-17に公開中

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