8PWK
| human HINT1 in complex with compound AT8003 | Descriptor: | Histidine triad nucleotide-binding protein 1, SODIUM ION, [(2~{R},3~{R},4~{R},5~{R})-5-[2-azanyl-6-(methylamino)purin-9-yl]-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate | Authors: | Zimberger, C, Canard, B, Ferron, F. | Deposit date: | 2023-07-20 | Release date: | 2024-07-31 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.095 Å) | Cite: | The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution. Plos Biol., 22, 2024
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8PTS
| human GUK1 in complex with compound AT8001 | Descriptor: | GLYCEROL, Guanylate kinase, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate | Authors: | Zimberger, C, Canard, B, Ferron, F. | Deposit date: | 2023-07-14 | Release date: | 2024-07-24 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution. Plos Biol., 22, 2024
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8QCH
| Human Adenosine deaminase-like protein in complex with compound AT8001 | Descriptor: | Adenosine deaminase-like protein, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | Authors: | Zimberger, C, canard, B, Ferron, F. | Deposit date: | 2023-08-26 | Release date: | 2024-07-31 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.442 Å) | Cite: | The activation cascade of the broad-spectrum antiviral bemnifosbuvir characterized at atomic resolution. Plos Biol., 22, 2024
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6ZPP
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8PK7
| Helical reconstruction of CHIKV nsP3 helical scaffolds | Descriptor: | Non-structural protein 3, ZINC ION | Authors: | Reguera, J, Hons, M, Zimberger, C, Ptchelkine, D, Jones, R, Desfosses, A. | Deposit date: | 2023-06-25 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | The alphavirus nsP3 protein forms helical tubular scaffolds important for viral replication and particle assembly To Be Published
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8PHZ
| Helical reconstruction of CHIKV nsP3 helical scaffolds | Descriptor: | Non-structural protein 3, ZINC ION | Authors: | Reguera, J, Hons, M, Zimberger, C, Ptchelkine, D, Jones, R, Desfosses, A. | Deposit date: | 2023-06-20 | Release date: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.35 Å) | Cite: | The alphavirus nsP3 protein forms helical tubular scaffolds important for viral replication and particle assembly To be published
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