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PDB: 493 件

7TVK
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Structural, Kinetic, and Mechanistic Analysis of the Wild-Type and Inactivated Malonate Semialdehyde Decarboxylase: A Structural Basis for the Decarboxylase and Hydratase Activities
分子名称: Malonate Semialdehyde Decarboxylase
著者Yang, W.J, Zhang, Y.J.
登録日2022-02-05
公開日2022-12-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Kinetic, Inhibition, and Structural Characterization of a Malonate Semialdehyde Decarboxylase-like Protein from Calothrix sp. PCC 6303: A Gateway to the non-Pro1 Tautomerase Superfamily Members.
Biochemistry, 2022
5YWI
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Crystal structure of Arabidopsis thaliana HPPD Truncated mutant complexed with NTBC
分子名称: 2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHYLENE}CYCLOHEXANE-1,3-DIONE, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION
著者Yang, W.C, Chen, J.N.
登録日2017-11-29
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Crystal structure of Arabidopsis thaliana HPPD Truncated mutant complexed with NTBC
To be published
5YWH
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Crystal structure of Arabidopsis thaliana HPPD complexed with Y13508
分子名称: 4-hydroxyphenylpyruvate dioxygenase, FE (III) ION, [1,3-diethyl-2,2-bis(oxidanylidene)-2$l^{6},1,3-benzothiadiazol-5-yl]-(1-methyl-5-oxidanyl-pyrazol-4-yl)methanone
著者Yang, W.C, Lin, H.Y.
登録日2017-11-29
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Crystal structure of Arabidopsis thaliana HPPD complexed with Y13508
To be published
7DA6
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Enterovirus 71 2A Protease mutant- C110A in complex with peptide inhibitor
分子名称: PHE-ARG-GLY-LYS, Polyprotein, ZINC ION
著者Yang, W.Z, Yuan, H.S.
登録日2020-10-15
公開日2021-08-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Efficient Strategy to Design Protease Inhibitors: Application to Enterovirus 71 2A Protease.
Acs Bio Med Chem Au, 2022
7VMB
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Crystal structure of IQSEC1-IQ motif, Sec7PH tandem in complex with calmodulin
分子名称: Calmodulin-1, GLYCEROL, IQ motif and SEC7 domain-containing protein 1
著者Yang, W, Zhang, M.
登録日2021-10-08
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99777377 Å)
主引用文献Ca2+-induced release of IQSEC2/BRAG1 autoinhibition under physiological and pathological conditions.
J.Cell Biol., 222, 2023
7WWH
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Crystal structure of the Geobacillus thermoglucosidasius feruloyl esterase GthFAE
分子名称: Alpha/beta hydrolase
著者Yang, W, Wu, Y.
登録日2022-02-12
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure-guided rational design of the Geobacillus thermoglucosidasius feruloyl esterase GthFAE to improve its thermostability.
Biochem.Biophys.Res.Commun., 600, 2022
6S8N
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Cryo-EM structure of LptB2FGC in complex with lipopolysaccharide
分子名称: 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, Inner membrane protein yjgQ, ...
著者Tang, X.D, Chang, S.H, Luo, Q.H, Zhang, Z.Y, Qiao, W, Xu, C.H, Zhang, C.B, Niu, Y, Yang, W.X, Wang, T, Zhang, Z.B, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2019-07-10
公開日2019-09-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
Nat Commun, 10, 2019
6S8H
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Cryo-EM structure of LptB2FG in complex with LPS
分子名称: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, ...
著者Tang, X.D, Chang, S.H, Luo, Q.H, Zhang, Z.Y, Qiao, W, Xu, C.H, Zhang, C.B, Niu, Y, Yang, W.X, Wang, T, Zhang, Z.B, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2019-07-10
公開日2019-09-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
Nat Commun, 10, 2019
6S8G
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Cryo-EM structure of LptB2FGC in complex with AMP-PNP
分子名称: Inner membrane protein yjgQ, LPS export ABC transporter permease LptF, Lipopolysaccharide ABC transporter, ...
著者Tang, X.D, Chang, S.H, Luo, Q.H, Zhang, Z.Y, Qiao, W, Xu, C.H, Zhang, C.B, Niu, Y, Yang, W.X, Wang, T, Zhang, Z.B, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2019-07-10
公開日2019-09-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism.
Nat Commun, 10, 2019
4WWX
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Crystal structure of the core RAG1/2 recombinase
分子名称: V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, ZINC ION
著者Kim, M.S, Lapkouski, M, Yang, W, Gellert, M.
登録日2014-11-12
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2001 Å)
主引用文献Crystal structure of the V(D)J recombinase RAG1-RAG2.
Nature, 518, 2015
4XVM
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Binary complex of human polymerase nu and DNA with the finger domain closed and thumb domain rotated out
分子名称: DNA (5'-D(*CP*TP*AP*GP*CP*GP*TP*CP*A)-3'), DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*G)-3'), DNA polymerase nu
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
4XVI
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Binary complex of human polymerase nu and DNA with the finger domain ajar
分子名称: DNA (5'-D(*AP*CP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*CP*AP*G)-3'), DNA polymerase nu
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
4XVK
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BU of 4xvk by Molmil
Binary complex of human polymerase nu and DNA with the finger domain closed
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*GP*AP*TP*CP*TP*GP*AP*CP*GP*CP*TP*AP*CP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*GP*TP*AP*GP*CP*GP*TP*CP*A)-3'), ...
著者Lee, Y.-S, Yang, W.
登録日2015-01-27
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis.
Nat.Struct.Mol.Biol., 22, 2015
1FIP
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THE STRUCTURE OF FIS MUTANT PRO61ALA ILLUSTRATES THAT THE KINK WITHIN THE LONG ALPHA-HELIX IS NOT DUE TO THE PRESENCE OF THE PROLINE RESIDUE
分子名称: FACTOR FOR INVERSION STIMULATION (FIS), UNKNOWN PEPTIDE, POSSIBLY PART OF THE UNOBSERVED RESIDUES IN ENTITY 1
著者Yuan, H.S, Wang, S.S, Yang, W.-Z, Finkel, S.E, Johnson, R.C.
登録日1994-09-26
公開日1995-02-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of Fis mutant Pro61Ala illustrates that the kink within the long alpha-helix is not due to the presence of the proline residue.
J.Biol.Chem., 269, 1994
1K18
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Minimized Average NMR Structure of the Zinc Finger Domain of Human DNA Polymerase-alpha
分子名称: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT
著者Evanics, F, Maurmann, L, Yang, W.W, Bose, R.N.
登録日2001-09-24
公開日2003-06-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance structures of the zinc finger domain of human DNA polymerase-alpha.
Biochim.Biophys.Acta, 1651, 2003
8DOL
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BU of 8dol by Molmil
Mechanism of regulation of the Helicobacter pylori Cagbeta ATPase by CagZ
分子名称: Cag pathogenicity island protein (Cag5), DI(HYDROXYETHYL)ETHER, SULFATE ION
著者Wu, X, Zhao, Y, Yang, W, Sun, L, Ye, X, Jiang, M, Wang, Q, Wang, Q, Zhang, X, Wu, Y.
登録日2022-07-13
公開日2023-02-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of regulation of the Helicobacter pylori Cag beta ATPase by CagZ.
Nat Commun, 14, 2023
2V88
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Crystal structure of RAG2-PHD finger in complex with H3R2me2sK4me2 peptide
分子名称: H3R2ME2SK4ME3 PEPTIDE, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-03
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V89
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Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide at 1.1A resolution
分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-03
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Rag2 Phd Finger Couples Histone H3 Lysine 4 Trimethylation with V(D)J Recombination.
Nature, 450, 2007
2V86
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Crystal structure of RAG2-PHD finger in complex with H3R2me2aK4me3 peptide
分子名称: H3R2ME2AK4ME3 PEPTIDE, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V85
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Crystal structure of RAG2-PHD finger in complex with H3R2me1K4me3 peptide
分子名称: H3R2ME1K4ME3 PEPTIDE, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V87
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Crystal structure of RAG2-PHD finger in complex with H3R2me2sK4me3 peptide
分子名称: HISTONE H3.2, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V83
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Crystal structure of RAG2-PHD finger in complex with H3K4me3 peptide
分子名称: HISTONE H3, VDJ RECOMBINATION-ACTIVATING PROTEIN 2, ZINC ION
著者Ramon-Maiques, S, Yang, W.
登録日2007-08-02
公開日2007-12-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Plant Homeodomain Finger of Rag2 Recognizes Histone H3 Methylated at Both Lysine-4 and Arginine-2.
Proc.Natl.Acad.Sci.USA, 104, 2007
1ZZS
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Bovine eNOS N368D single mutant with L-N(omega)-Nitroarginine-(4R)-Amino-L-Proline Amide Bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, GLYCEROL, ...
著者Li, H, Flinspach, M.L, Igarashi, J, Jamal, J, Yang, W, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
登録日2005-06-14
公開日2005-12-06
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
1ZZQ
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Rat nNOS D597N mutant with L-N(omega)-Nitroarginine-(4R)-amino-L-proline amide bound
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, D-MANNITOL, ...
著者Li, H, Flinspach, M.L, Igarashi, J, Jamal, J, Yang, W, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L.
登録日2005-06-14
公開日2005-12-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases.
Biochemistry, 44, 2005
1ETK
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THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A
分子名称: FACTOR FOR INVERSION STIMULATION
著者Cheng, Y.S, Yang, W.Z, Johnson, R.C, Yuan, H.S.
登録日2000-04-13
公開日2000-10-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of the transcriptional activation on Fis: crystal structures of six Fis mutants with different activation properties.
J.Mol.Biol., 302, 2000

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