8HOW
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![BU of 8how by Molmil](/molmil-images/mine/8how) | Crystal structure of AtHPPD-Y191052 complex | Descriptor: | 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(2-phenylethyl)quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Yang, G.-F, Lin, H.-Y, Dong, J. | Deposit date: | 2022-12-11 | Release date: | 2023-01-25 | Last modified: | 2023-02-01 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Discovery of Subnanomolar Inhibitors of 4-Hydroxyphenylpyruvate Dioxygenase via Structure-Based Rational Design. J.Agric.Food Chem., 71, 2023
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8GWD
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![BU of 8gwd by Molmil](/molmil-images/mine/8gwd) | Crystal structure of AtHPPD-Y18734 complex | Descriptor: | 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-[(1S)-1-phenylethyl]quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Yang, G.-F, Lin, H.-Y, Dong, J. | Deposit date: | 2022-09-16 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.889 Å) | Cite: | Crystal structure of AtHPPD-Y18734 complex To Be Published
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8H6B
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![BU of 8h6b by Molmil](/molmil-images/mine/8h6b) | Crystal structure of AtHPPD complexed with YH20702 | Descriptor: | 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, N-(1-methyl-1,2,3,4-tetrazol-5-yl)-1-pentyl-pyrrolo[2,3-b]pyridine-4-carboxamide | Authors: | Yang, G.-F. | Deposit date: | 2022-10-16 | Release date: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.897 Å) | Cite: | Crystal structure of AtHPPD complexed with YH20702 To Be Published
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8H6A
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![BU of 8h6a by Molmil](/molmil-images/mine/8h6a) | Crystal structure of AtHPPD complexed with YH21477 | Descriptor: | 1-[(2-chlorophenyl)methyl]-3-methyl-N-(1-methyl-1,2,3,4-tetrazol-5-yl)-2-oxidanylidene-benzimidazole-4-carboxamide, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Yang, G.-F. | Deposit date: | 2022-10-16 | Release date: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Crystal structure of AtHPPD complexed with YH20702 To Be Published
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8WQM
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![BU of 8wqm by Molmil](/molmil-images/mine/8wqm) | Complex structure of AtHPPD with Atovaquone | Descriptor: | 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Yang, G.-F, Lin, H.-Y, Dong, J. | Deposit date: | 2023-10-11 | Release date: | 2024-03-13 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.796 Å) | Cite: | Complex structure of AtHPPD with Atovaquone To Be Published
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7VO8
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![BU of 7vo8 by Molmil](/molmil-images/mine/7vo8) | Structure of AtHPPD complexed with LSY-1 | Descriptor: | 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, N-[6-[[9-(dimethylamino)-12H-benzo[a]phenoxazin-5-yl]amino]hexyl]-4-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-[oxidanyl(oxidanylidene)-$l^4-azanyl]benzamide | Authors: | Yang, G.-F, Dong, J. | Deposit date: | 2021-10-12 | Release date: | 2022-09-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | In vivo diagnostics of abiotic plant stress responses via in situ real-time fluorescence imaging Plant Physiol., 190, 2022
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7WJ8
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![BU of 7wj8 by Molmil](/molmil-images/mine/7wj8) | Complex structure of AtHPPD-PyQ1 | Descriptor: | 2-pyren-1-yloxyethyl 2-[1,5-dimethyl-2,4-bis(oxidanylidene)-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazolin-3-yl]ethanoate, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Yang, G.-F, Lin, H.-Y, Dong, J. | Deposit date: | 2022-01-05 | Release date: | 2022-09-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.805 Å) | Cite: | Design of an HPPD fluorescent probe and visualization of plant responses to abiotic stress Adv Agrochem, 2022
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7WJJ
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![BU of 7wjj by Molmil](/molmil-images/mine/7wjj) | Complex structure of AtHPPD-PyQ2 | Descriptor: | 2-[1,5-dimethyl-2,4-bis(oxidanylidene)-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazolin-3-yl]-N-(2-pyren-1-yloxyethyl)ethanamide, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Yang, G.-F, Lin, H.-Y, Dong, J. | Deposit date: | 2022-01-06 | Release date: | 2022-09-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.603 Å) | Cite: | Design of an HPPD fluorescent probe and visualization of plant responses to abiotic stress Adv Agrochem, 2022
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7WJK
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![BU of 7wjk by Molmil](/molmil-images/mine/7wjk) | Complex structure of AtHPPD-ZWJ | Descriptor: | 3-[2-[4-[[4-[2,2-bis(fluoranyl)-4,6,10,12-tetramethyl-1,3-diaza-2$l^{4}-boratricyclo[7.3.0.0^{3,7}]dodeca-4,6,9,11-tetraen-8-yl]phenoxy]methyl]-1,2,3-triazol-1-yl]ethyl]-1,5-dimethyl-6-[(1S)-2-oxidanyl-6-oxidanylidene-cyclohex-2-en-1-yl]carbonyl-quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Yang, G.-F, Lin, H.-Y, Dong, J. | Deposit date: | 2022-01-06 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.704 Å) | Cite: | Complex structure of AtHPPD-PyQ1 To Be Published
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6M6D
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![BU of 6m6d by Molmil](/molmil-images/mine/6m6d) | Structure of HPPD complexed with a synthesized inhibitor | Descriptor: | 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(3-trimethylsilylprop-2-ynyl)quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Lin, H.-Y, Yang, W.-C, Yang, G.-F. | Deposit date: | 2020-03-14 | Release date: | 2021-03-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.842 Å) | Cite: | Structure-Guided Discovery of Silicon-Containing Subnanomolar Inhibitor of Hydroxyphenylpyruvate Dioxygenase as a Potential Herbicide. J.Agric.Food Chem., 69, 2021
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3TGU
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![BU of 3tgu by Molmil](/molmil-images/mine/3tgu) | Cytochrome bc1 complex from chicken with pfvs-designed moa inhibitor bound | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, Coenzyme Q10, ... | Authors: | Huang, L.-S, Yang, G.-F, Berry, E.A. | Deposit date: | 2011-08-17 | Release date: | 2012-07-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex. J.Am.Chem.Soc., 134, 2012
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8HID
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![BU of 8hid by Molmil](/molmil-images/mine/8hid) | HUMAN ERYTHROCYTE CATALSE COMPLEXED WITH BT-Br | Descriptor: | (~{S})-azanyl-[2-[[3-bromanyl-4-(diethylamino)phenyl]methyl]hydrazinyl]methanethiol, Catalase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Lin, H.-Y, Yang, G.-F. | Deposit date: | 2022-11-19 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A catalase inhibitor: Targeting the NADPH-binding site for castration-resistant prostate cancer therapy. Redox Biol, 63, 2023
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8GQT
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![BU of 8gqt by Molmil](/molmil-images/mine/8gqt) | |
8IM2
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![BU of 8im2 by Molmil](/molmil-images/mine/8im2) | Crystal structure of human HPPD complexed with NTBC | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHYLENE}CYCLOHEXANE-1,3-DIONE, 4-hydroxyphenylpyruvate dioxygenase, ... | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-03-05 | Release date: | 2023-10-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Structure-based discovery of pyrazole-benzothiadiazole hybrid as human HPPD inhibitors. Structure, 31, 2023
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8JBW
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![BU of 8jbw by Molmil](/molmil-images/mine/8jbw) | Crystal structure of ZtHPPD-(+)-Usnic acid complex | Descriptor: | (9bR)-2,6-diethanoyl-8,9b-dimethyl-3,7,9-tris(oxidanyl)dibenzofuran-1-one, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Lin, H.-Y, Dong, J, Yang, G.-F. | Deposit date: | 2023-05-09 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Discovery and Development of 4-Hydroxyphenylpyruvate Dioxygenase as a Novel Crop Fungicide Target. J.Agric.Food Chem., 71, 2023
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8HZA
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![BU of 8hza by Molmil](/molmil-images/mine/8hza) | Crystal structure of AtHPPD-YH20326 complex | Descriptor: | 1,4-dimethyl-3-(oxan-4-ylmethyl)-5-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-benzimidazol-2-one, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-08 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Crystal structure of AtHPPD-YH20326 complex To Be Published
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8HXH
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![BU of 8hxh by Molmil](/molmil-images/mine/8hxh) | Crystal structure of AtHPPD-Y18024 complex | Descriptor: | 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-propyl-quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-04 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.992 Å) | Cite: | Crystal structure of AtHPPD-Y18024 complex To Be Published
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8HYS
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![BU of 8hys by Molmil](/molmil-images/mine/8hys) | Crystal structure of AtHPPD-Y19802 complex | Descriptor: | 1-methyl-3-[2-methyl-6-methylsulfonyl-3-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-phenyl]-6-(trifluoromethyl)pyrimidine-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-07 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of AtHPPD-Y19802 complex To Be Published
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8HWR
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![BU of 8hwr by Molmil](/molmil-images/mine/8hwr) | Crystal structure of AtHPPD-Y191193 complex | Descriptor: | 4-hydroxyphenylpyruvate dioxygenase, 6-chloranyl-3-cyclopentyl-1-methyl-7-(2-oxidanyl-6-oxidanylidene-cyclohexa-1,3-dien-1-yl)carbonyl-quinazoline-2,4-dione, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-02 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Crystal structure of AtHPPD-Y191193 complex To Be Published
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8HYP
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![BU of 8hyp by Molmil](/molmil-images/mine/8hyp) | Crystal structure of AtHPPD-Y18400 complex | Descriptor: | 3-[(4-fluorophenyl)methyl]-1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-07 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.749 Å) | Cite: | Crystal structure of AtHPPD-Y18400 complex To Be Published
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8HZ7
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![BU of 8hz7 by Molmil](/molmil-images/mine/8hz7) | Crystal structure of AtHPPD-Y181135 complex | Descriptor: | 3-butyl-5-methyl-6-[(2-methyl-3-oxidanylidene-1H-pyrazol-4-yl)carbonyl]-1,2,3-benzotriazin-4-one, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-08 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Crystal structure of AtHPPD-Y181135 complex To Be Published
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8I0G
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![BU of 8i0g by Molmil](/molmil-images/mine/8i0g) | Crystal structure of AtHPPD-Y19543 complex | Descriptor: | 3-[(4-fluorophenyl)methyl]-5-methyl-6-[(2-methyl-3-oxidanylidene-1H-pyrazol-4-yl)carbonyl]-1,2,3-benzotriazin-4-one, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-10 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.992 Å) | Cite: | Crystal structure of AtHPPD-Y19543 complex To Be Published
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8I36
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![BU of 8i36 by Molmil](/molmil-images/mine/8i36) | Crystal structure of AtHPPD-Y18980 complex | Descriptor: | 1,5-dimethyl-3-(naphthalen-1-ylmethyl)-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-16 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.887 Å) | Cite: | Crystal structure of AtHPPD-Y18980 complex To Be Published
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8I2P
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![BU of 8i2p by Molmil](/molmil-images/mine/8i2p) | Crystal structure of AtHPPD-Y19060 complex | Descriptor: | 3-(cyclopropylmethyl)-6-[(5-cyclopropyl-2-methyl-3-oxidanylidene-1H-pyrazol-4-yl)carbonyl]-1,5-dimethyl-quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-14 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.797 Å) | Cite: | Crystal structure of AtHPPD-Y19060 complex To Be Published
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8HXF
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![BU of 8hxf by Molmil](/molmil-images/mine/8hxf) | Crystal structure of AtHPPD-Y181188 complex | Descriptor: | 4-hydroxyphenylpyruvate dioxygenase, 6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-4-[[4-(trifluoromethyl)phenyl]methyl]-1,4-benzothiazin-3-one, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-04 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.697 Å) | Cite: | Crystal structure of AtHPPD-Y181188 complex To Be Published
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