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PDB: 146 results

7DHV
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BU of 7dhv by Molmil
The co-crystal structure of DYRK2 with a small molecule inhibitor 8
Descriptor: 2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine-4-carboxylic acid, Dual specificity tyrosine-phosphorylation-regulated kinase 2
Authors:Wei, T, Xiao, J.
Deposit date:2020-11-17
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.679 Å)
Cite:Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry.
Elife, 11, 2022
7DJO
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BU of 7djo by Molmil
The co-crystal structure of DYRK2 with a small molecule inhibitor 17
Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol
Authors:Wei, T, Xiao, J.
Deposit date:2020-11-20
Release date:2021-11-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry.
Elife, 11, 2022
7DL6
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BU of 7dl6 by Molmil
The co-crystal structure of DYRK2 with a small molecule inhibitor 18
Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol
Authors:Wei, T, Xiao, J.
Deposit date:2020-11-26
Release date:2021-12-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.648 Å)
Cite:Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry.
Elife, 11, 2022
7BYR
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BU of 7byr by Molmil
BD23-Fab in complex with the S ectodomain trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab23-Fab-Heavy Chain, ...
Authors:Zhu, Q, Wang, G, Xiao, J.
Deposit date:2020-04-24
Release date:2020-06-10
Last modified:2021-03-10
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells.
Cell, 182, 2020
7DXI
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BU of 7dxi by Molmil
Structure of Drosophila melanogaster GlcNAc-1-phosphotransferase
Descriptor: CALCIUM ION, FI02838p
Authors:Du, S, Xiao, J, Guopeng, W.
Deposit date:2021-01-19
Release date:2022-02-02
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structural insights into how GlcNAc-1-phosphotransferase directs lysosomal protein transport.
J.Biol.Chem., 298, 2022
7V20
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BU of 7v20 by Molmil
CryoEM structure of del68-76/del679-688 prefusion-stabilized spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Du, S, Xiao, J.
Deposit date:2021-08-07
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:CryoEM structure of del68-76/del679-688 prefusion-stabilized spike
To Be Published
7V23
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BU of 7v23 by Molmil
CryoEM structure of del68-76/del679-688 prefusion-stabilized spike in complex with the Fab of N12-9
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Du, S, Xiao, J.
Deposit date:2021-08-07
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:CryoEM structure of del68-76/del679-688 prefusion-stabilized spike in complex with the Fab of N12-9
To Be Published
7WR9
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BU of 7wr9 by Molmil
Local CryoEM structure of the SARS-CoV S2P in complex with BD55-3152 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BD55-3152H, BD55-3152L, ...
Authors:Du, S, Xiao, J.Y.
Deposit date:2022-01-26
Release date:2023-02-01
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Local CryoEM structure of the SARS-CoV S2P in complex with BD55-3152 Fab
To Be Published
7YTE
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BU of 7yte by Molmil
crystal structure of human FcmR-D1 bound to IgM C4-domain
Descriptor: Fas apoptotic inhibitory molecule 3, Ig mu chain C region secreted form
Authors:Li, Y, Shen, H, Xiao, J.
Deposit date:2022-08-14
Release date:2023-02-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
7WCK
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BU of 7wck by Molmil
Local CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWA9 Fab
Descriptor: SWA9H, SWA9L, Surface glycoprotein
Authors:Du, S, Xiao, J.Y.
Deposit date:2021-12-20
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Local CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWA9 Fab
To Be Published
7WCP
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BU of 7wcp by Molmil
CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWC11 Fab
Descriptor: SWC11H, SWC11L, Surface glycoprotein
Authors:Du, S, Xiao, J.Y.
Deposit date:2021-12-20
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWC11 Fab
To Be Published
7WCU
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BU of 7wcu by Molmil
Local CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWC11 Fab
Descriptor: SWC11H, SWC11L, Surface glycoprotein
Authors:Du, S, Xiao, J.Y.
Deposit date:2021-12-20
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Local CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWC11 Fab
To Be Published
7WCH
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BU of 7wch by Molmil
CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWA9 Fab
Descriptor: SWA9H, SWA9L, Surface glycoprotein
Authors:Du, S, Xiao, J.Y.
Deposit date:2021-12-20
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:CryoEM structure of the SARS-CoV-2 S6P(B.1.617.2) in complex with SWA9 Fab
To Be Published
7EYA
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BU of 7eya by Molmil
Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-804 Fab
Descriptor: BD-804H, BD-804L, Spike glycoprotein, ...
Authors:Du, S, Xiao, J.
Deposit date:2021-05-30
Release date:2021-09-08
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.
Cell Res., 31, 2021
7EY0
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BU of 7ey0 by Molmil
Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-813 Fab and BD-744 Fab
Descriptor: BD-744H, BD-744L, BD-813H, ...
Authors:Du, S, Xiao, J.
Deposit date:2021-05-29
Release date:2021-09-08
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.
Cell Res., 31, 2021
7V22
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BU of 7v22 by Molmil
Local CryoEM structure del68-76/del679-688 prefusion-stabilized spike
Descriptor: Spike glycoprotein
Authors:Du, S, Xiao, J.
Deposit date:2021-08-07
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Local CryoEM structure del68-76/del679-688 prefusion-stabilized spike
To Be Published
7V24
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BU of 7v24 by Molmil
Local CryoEM structure of del68-76/del679-688 prefusion-stabilized spike in complex with the Fab of N12-9
Descriptor: Spike glycoprotein, the heavy chain of N12-9 Fab, the lignt chain of N12-9 Fab
Authors:Du, S, Xiao, J.
Deposit date:2021-08-07
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Local CryoEM structure of del68-76/del679-688 prefusion-stabilized spike in complex with the Fab of N12-9
To Be Published
2CKA
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BU of 2cka by Molmil
Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction
Descriptor: CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8
Authors:Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E.
Deposit date:2006-04-14
Release date:2007-05-08
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
To be Published
7DH3
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BU of 7dh3 by Molmil
The co-crystal structure of DYRK2 with a small molecule inhibitor 5
Descriptor: 2,7-dimethoxy-9-piperidin-4-ylsulfanyl-acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2
Authors:Wei, T, Xiao, J.
Deposit date:2020-11-12
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:The co-crystal structure of DYRK2 with a small molecule inhibitor 5
To Be Published
7DNR
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BU of 7dnr by Molmil
Crystal Structure of Zn-bound SIS Domain of Glucosamine-6-P Synthase from E. coli
Descriptor: Glutamine--fructose-6-phosphate aminotransferase [isomerizing], ZINC ION
Authors:Gao, C, Xiao, J.
Deposit date:2020-12-10
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of Metal-binding Proteins by Thermal Proteome Profiling
To Be Published
2CKC
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BU of 2ckc by Molmil
Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction
Descriptor: CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
Authors:Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E.
Deposit date:2006-04-14
Release date:2007-05-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
To be Published

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數據於2024-07-24公開中

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