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2IQG
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Crystal Structure of Hydroxyethyl Secondary Amine-based Peptidomimetic Inhibitor of Human Beta-Secretase (BACE)
Descriptor: Beta-secretase 1, N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-IODOBENZYL)AMINO]PROPYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE
Authors:Benson, T.E, Woods, D.D, Prince, D.B, Tomasselli, A.G, Emmons, T.L.
Deposit date:2006-10-13
Release date:2007-02-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design, Synthesis, and Crystal Structure of Hydroxyethyl Secondary Amine-Based Peptidomimetic Inhibitors of Human beta-Secretase.
J.Med.Chem., 50, 2007

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