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PDB: 74 件
4UE9
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Complex of D. melanogaster eIF4E with the 4E-binding protein 4E-T
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4UEC
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BU of 4uec by Molmil
Complex of D. melanogaster eIF4E with eIF4G and cap analog
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, ...
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
5T47
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Crystal structure of the D. melanogaster eIF4E-eIF4G complex
分子名称: Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, isoform A, ...
著者Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
登録日2016-08-29
公開日2016-10-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
5T48
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Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact
分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, ...
著者Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E.
登録日2016-08-29
公開日2016-10-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
6H3Z
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BU of 6h3z by Molmil
Crystal structure of a C-terminal MIF4G domain in NOT1
分子名称: CCR4-not transcription complex subunit 1, SODIUM ION
著者Raisch, T, Sandmeir, F, Weichenrieder, O, Valkov, E, Izaurralde, E.
登録日2018-07-19
公開日2018-11-07
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex.
J. Struct. Biol., 204, 2018
4UEA
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Complex of D. melanogaster eIF4E with a designed 4E-binding protein (Form I)
分子名称: DESIGNED 4E-BP, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
5ABY
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BU of 5aby by Molmil
Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli
分子名称: 4E-BINDING PROTEIN MEXTLI, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-3, GLYCEROL, ...
著者Peter, D, Weichenrieder, O.
登録日2015-08-09
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
5ABV
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BU of 5abv by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, GH11071P
著者Peter, D, Weichenrieder, O.
登録日2015-08-09
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
5AOX
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BU of 5aox by Molmil
Human Alu RNA retrotransposition complex in the ribosome-stalling conformation
分子名称: ACETATE ION, ALU JO CONSENSUS RNA, DI(HYDROXYETHYL)ETHER, ...
著者Ahl, V, Weichenrieder, O.
登録日2015-09-12
公開日2015-11-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Retrotransposition and Crystal Structure of an Alu Rnp in the Ribosome-Stalling Conformation.
Mol.Cell, 60, 2015
5ABX
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Complex of C. elegans eIF4E-3 with the 4E-binding protein Mextli and cap analog
分子名称: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者Peter, D, Weichenrieder, O.
登録日2015-08-09
公開日2015-09-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
5ABU
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BU of 5abu by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli and cap analog
分子名称: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, CHLORIDE ION, ...
著者Peter, D, Weichenrieder, O.
登録日2015-08-09
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
2V0R
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BU of 2v0r by Molmil
crystal structure of a hairpin exchange variant (LTx) of the targeting LINE-1 retrotransposon endonuclease
分子名称: LTX, SULFATE ION
著者Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O.
登録日2007-05-17
公開日2007-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease
Nucleic Acids Res., 35, 2007
2V0S
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BU of 2v0s by Molmil
crystal structure of a hairpin exchange variant (LR1) of the targeting LINE-1 retrotransposon endonuclease
分子名称: GLYCEROL, LR1, MANGANESE (II) ION, ...
著者Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O.
登録日2007-05-17
公開日2007-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease.
Nucleic Acids Res., 35, 2007
2VC8
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BU of 2vc8 by Molmil
Crystal structure of the LSm domain of human EDC3 (enhancer of decapping 3)
分子名称: ENHANCER OF MRNA-DECAPPING PROTEIN 3
著者Tritschler, F, Hartmann, M.D, Weichenrieder, O.
登録日2007-09-19
公開日2007-10-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献A Divergent Sm Fold in Edc3 Proteins Mediates Dcp1 Binding and P-Body Targeting.
Mol.Cell.Biol., 27, 2007
2W7A
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BU of 2w7a by Molmil
Structure of the human LINE-1 ORF1p central domain
分子名称: LINE-1 ORF1P, MALONATE ION
著者Khazina, E, Weichenrieder, O.
登録日2008-12-22
公開日2009-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Non-Ltr Retrotransposons Encode Noncanonical Rrm Domains in Their First Open Reading Frame.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WAY
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BU of 2way by Molmil
Structure of the human DDX6 C-terminal domain in complex with an EDC3- FDF peptide
分子名称: ATP-DEPENDENT RNA HELICASE DDX6, ENHANCER OF MRNA-DECAPPING PROTEIN 3, GLYCEROL
著者Tritschler, F, Weichenrieder, O.
登録日2009-02-18
公開日2009-03-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Mutually Exclusive Anchoring of P Body Components Edc3 and Tral to the Dead Box Protein Ddx6/Me31B.
Mol.Cell, 33, 2009
2YHA
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BU of 2yha by Molmil
Crystal Structure of the N. crassa QDE-2 AGO MID-PIWI Domains
分子名称: GLYCEROL, POST-TRANSCRIPTIONAL GENE SILENCING PROTEIN QDE-2, SULFATE ION
著者Boland, A, Weichenrieder, O.
登録日2011-04-27
公開日2011-06-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of the Mid-Piwi Lobe of a Eukaryotic Argonaute Protein
Proc.Natl.Acad.Sci.USA, 108, 2011
2YHB
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BU of 2yhb by Molmil
Crystal Structure of the N. crassa QDE-2 AGO MID-PIWI Domains
分子名称: GLYCEROL, POST-TRANSCRIPTIONAL GENE SILENCING PROTEIN QDE-2, SULFATE ION
著者Boland, A, Weichenrieder, O.
登録日2011-04-27
公開日2011-06-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Crystal Structure of the Mid-Piwi Lobe of a Eukaryotic Argonaute Protein
Proc.Natl.Acad.Sci.USA, 108, 2011
2WAX
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BU of 2wax by Molmil
Structure of the human DDX6 C-terminal domain in complex with an EDC3- FDF peptide
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ATP-DEPENDENT RNA HELICASE DDX6, ENHANCER OF MRNA-DECAPPING PROTEIN 3, ...
著者Tritschler, F, Weichenrieder, O.
登録日2009-02-18
公開日2009-03-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Mutually Exclusive Anchoring of P Body Components Edc3 and Tral to the Dead Box Protein Ddx6/Me31B.
Mol.Cell, 33, 2009
2WX4
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BU of 2wx4 by Molmil
Asymmetric trimer of the Drosophila melanogaster DCP1 C-terminal domain
分子名称: DECAPPING PROTEIN 1, SULFATE ION
著者Tritschler, F, Weichenrieder, O.
登録日2009-11-01
公開日2009-12-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dcp1 Forms Asymmetric Trimers to Assemble Into Active Mrna Decapping Complexes in Metazoa.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WX3
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BU of 2wx3 by Molmil
Asymmetric trimer of the human DCP1a C-terminal domain
分子名称: MRNA-DECAPPING ENZYME 1A
著者Tritschler, F, Motz, C, Weichenrieder, O.
登録日2009-11-01
公開日2009-12-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Dcp1 Forms Asymmetric Trimers to Assemble Into Active Mrna Decapping Complexes in Metazoa.
Proc.Natl.Acad.Sci.USA, 106, 2009
2XES
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BU of 2xes by Molmil
Human PatL1 C-terminal domain (loop variant)
分子名称: POTASSIUM ION, PROTEIN PAT1 HOMOLOG 1, THIOCYANATE ION
著者Tritschler, F, Weichenrieder, O.
登録日2010-05-17
公開日2010-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The C-Terminal Alpha-Alpha Superhelix of Pat is Required for Mrna Decapping in Metazoa.
Embo J., 29, 2010
2XDY
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BU of 2xdy by Molmil
Crystal structure of the N. crassa QDE-2 AGO MID domain
分子名称: GLYCEROL, POST-TRANSCRIPTIONAL GENE SILENCING PROTEIN QDE-2, SULFATE ION
著者Boland, A, Tritschler, F, Weichenrieder, O.
登録日2010-05-10
公開日2010-06-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure and Ligand Binding of the Mid Domain of a Eukaryotic Argonaute Protein.
Embo Rep., 11, 2010
2XEQ
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BU of 2xeq by Molmil
Human PatL1 C-terminal domain
分子名称: PAT1 HOMOLOG 1,
著者Tritschler, F, Weichenrieder, O.
登録日2010-05-17
公開日2010-06-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The C-Terminal Alpha-Alpha Superhelix of Pat is Required for Mrna Decapping in Metazoa.
Embo J., 29, 2010
2XER
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BU of 2xer by Molmil
Human PatL1 C-terminal domain (loop variant with sulfates)
分子名称: PAT1 HOMOLOG 1, SULFATE ION
著者Tritschler, F, Weichenrieder, O.
登録日2010-05-17
公開日2010-06-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The C-Terminal Alpha-Alpha Superhelix of Pat is Required for Mrna Decapping in Metazoa.
Embo J., 29, 2010

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