7ZPC
| CDK2 in complex 9K-DOS | Descriptor: | Cyclin-dependent kinase 2, ~{N}-(1-methylpyrazol-4-yl)-5-phenyl-pyrazolo[1,5-a]pyrimidine-7-carboxamide | Authors: | Watt, J.E, Martin, M.P, Noble, M.E.N. | Deposit date: | 2022-04-27 | Release date: | 2023-02-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Build-Couple-Transform: A Paradigm for Lead-like Library Synthesis with Scaffold Diversity. J.Med.Chem., 65, 2022
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2KP4
| Structure of 2'F-ANA/RNA hybrid duplex | Descriptor: | DNA (5'-D(*(GFL)P*(CFL)P*(TAF)P*(A5L)P*(TAF)P*(A5L)P*(A5L)P*(TAF)P*(GFL)P*(GFL))-3'), RNA (5'-R(*CP*CP*AP*UP*UP*AP*UP*AP*GP*C)-3') | Authors: | Gonzalez, C, Martin-Pintado, N, Watts, J, Gomez-Pinto, I, Dhama, M, Orozco, M, Schwartzentruber, J, Portella, G. | Deposit date: | 2009-10-06 | Release date: | 2010-02-09 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility. Nucleic Acids Res., 38, 2010
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2KP3
| Structure of ANA-RNA hybrid duplex | Descriptor: | RNA (5'-R(*(GAO)P*(CAR)P*(UAR)P*(A5O)P*(UAR)P*(A5O)P*(A5O)P*(UAR)P*(GAO)P*(GAO))-3'), RNA (5'-R(*CP*CP*AP*UP*UP*AP*UP*AP*GP*C)-3') | Authors: | Gonzalez, C, Martn-Pintado, N, Watts, J, Gomez-Pinto, I, Dhama, M, Orozco, M, Schwartzentruber, J, Portella, G. | Deposit date: | 2009-10-06 | Release date: | 2010-02-09 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility. Nucleic Acids Res., 38, 2010
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1P9P
| The Crystal Structure of a M1G37 tRNA Methyltransferase, TrmD | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, tRNA (Guanine-N(1)-)-methyltransferase | Authors: | Elkins, P.A, Watts, J.M, Zalacain, M, Van Thiel, A, Vitaszka, P.R, Redlak, M, Andraos-Selim, C, Rastinejad, F, Holmes, W.M. | Deposit date: | 2003-05-12 | Release date: | 2004-05-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insights into Catalysis by a Knotted TrmD tRNA Methyltransferase. J.Mol.Biol., 333, 2003
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6RSS
| Solution structure of the fourth WW domain of WWP2 with GB1-tag | Descriptor: | NEDD4-like E3 ubiquitin-protein ligase WWP2 | Authors: | Wahl, L.C, Watt, J.E, Tolchard, J, Blumenschein, T.M.A, Chantry, A. | Deposit date: | 2019-05-22 | Release date: | 2019-10-09 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Smad7 Binds Differently to Individual and Tandem WW3 and WW4 Domains of WWP2 Ubiquitin Ligase Isoforms. Int J Mol Sci, 20, 2019
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