6UWL
 
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6V5L
 | | The HADDOCK structure model of GDP KRas in complex with its allosteric inhibitor E22 | | 分子名称: | (2R)-2-[2-(1H-indole-3-carbonyl)hydrazinyl]-2-phenylacetamide, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Wang, X, Gupta, A.K, Prakash, P, Putkey, J.P, Gorfe, A.A. | | 登録日 | 2019-12-04 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Multi target ensemble based virtual screening yields novel allosteric KRAS inhibitors at high success rate
Chemical Biology & Drug Design, 94, 2019
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7WLC
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7WED
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6VRO
 | | The structure of the PP2A B56 subunit AIM1 complex | | 分子名称: | Beta/gamma crystallin domain-containing protein 1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | | 著者 | Wang, X, Page, R, Peti, W. | | 登録日 | 2020-02-08 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment.
Elife, 9, 2020
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7WEA
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7WEC
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7WE8
 | | SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv265 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 265, ... | | 著者 | Wang, X, Wang, L. | | 登録日 | 2021-12-23 | | 公開日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
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7WE7
 | | SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv282 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 282, ... | | 著者 | Wang, X, Wang, L. | | 登録日 | 2021-12-23 | | 公開日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants.
Nature, 603, 2022
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7WEB
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7WEE
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6NJD
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6NII
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6UWF
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6X15
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3HBF
 | | Structure of UGT78G1 complexed with myricetin and UDP | | 分子名称: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Flavonoid 3-O-glucosyltransferase, URIDINE-5'-DIPHOSPHATE | | 著者 | Wang, X, Modolo, L, Li, L, Dixon, R. | | 登録日 | 2009-05-04 | | 公開日 | 2009-09-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of glycosyltransferase UGT78G1 reveal the molecular basis for glycosylation and deglycosylation of (iso)flavonoids.
J.Mol.Biol., 392, 2009
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5XEX
 | | Crystal structure of S.aureus PNPase catalytic domain | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, PYROPHOSPHATE, ... | | 著者 | Wang, X, Zhang, X, Zang, J. | | 登録日 | 2017-04-06 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Enolase binds to RnpA in competition with PNPase in Staphylococcus aureus
FEBS Lett., 591, 2017
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7XMX
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7XMZ
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5X6O
 | | Intact ATR/Mec1-ATRIP/Ddc2 complex | | 分子名称: | DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1 | | 著者 | Wang, X, Ran, T, Cai, G. | | 登録日 | 2017-02-22 | | 公開日 | 2017-12-20 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | 3.9 angstrom structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP.
Science, 358, 2017
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7X2H
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4JDZ
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4JE0
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5WTE
 | | Cryo-EM structure for Hepatitis A virus full particle | | 分子名称: | VP1, VP2, VP3 | | 著者 | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | | 登録日 | 2016-12-11 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5WTG
 | | Crystal structure of the Fab fragment of anti-HAV antibody R10 | | 分子名称: | FAB Heavy chain, FAB Light chain | | 著者 | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | | 登録日 | 2016-12-11 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.907 Å) | | 主引用文献 | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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