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PDB: 461 results

7GZH
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Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0000670-001
Descriptor: (3R)-3-(4-bromophenyl)-3-[(1H-pyrrolo[2,3-b]pyridine-5-carbonyl)amino]propanoic acid, Non-structural protein 3
Authors:Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F.
Deposit date:2024-01-23
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre
To Be Published
7H11
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Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0013392-001
Descriptor: 7-[(1R)-1-{[(6M)-6-(2,5-dihydrofuran-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-2-methylpropyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3
Authors:Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F.
Deposit date:2024-01-23
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre
To Be Published
7GZZ
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Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0011184-001
Descriptor: 2-[(4M)-4-(4-{[(1S)-1-(1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~-benzothiopyran-7-yl)-2-methylpropyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-1H-pyrazol-1-yl]-N-methylacetamide, Papain-like protease nsp3
Authors:Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F.
Deposit date:2024-01-23
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.166 Å)
Cite:Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre
To Be Published
7H1D
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BU of 7h1d by Molmil
Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0011198-001
Descriptor: 4-{[(1R)-1-(1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~-benzothiopyran-7-yl)-2-methylpropyl]amino}-N-[(3R)-1-methylpyrrolidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Papain-like protease nsp3
Authors:Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F.
Deposit date:2024-01-23
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre
To Be Published
7H0C
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BU of 7h0c by Molmil
Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0012349-001
Descriptor: 4-{[(1R)-1-(1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~-benzothiopyran-7-yl)-2-methylpropyl]amino}-N-ethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Papain-like protease nsp3
Authors:Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F.
Deposit date:2024-01-23
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.429 Å)
Cite:Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre
To Be Published
7H15
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BU of 7h15 by Molmil
Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0013387-001
Descriptor: 7-[(1R)-1-{[(6M)-6-{2-[2-(dimethylamino)ethoxy]pyridin-4-yl}-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-2-methylpropyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3
Authors:Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F.
Deposit date:2024-01-23
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre
To Be Published
1CN0
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BU of 1cn0 by Molmil
CRYSTAL STRUCTURE OF D(ACCCT)
Descriptor: DNA (5'-D(*AP*CP*CP*CP*T)-3')
Authors:Weil, J, Min, T, Cheng, Y, Wang, S, Sutherland, C, Sinha, N, Kang, C.
Deposit date:1999-05-24
Release date:2000-05-24
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Stabilization of the i-motif by intramolecular adenine-adenine-thymine base triple in the structure of d(ACCCT).
Acta Crystallogr.,Sect.D, 55, 1999
1BQJ
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BU of 1bqj by Molmil
CRYSTAL STRUCTURE OF D(ACCCT)
Descriptor: DNA (5'-D(*AP*CP*CP*CP*T)-3')
Authors:Weil, J, Min, T, Yang, C, Wang, S, Sutherland, C, Sinha, N, Kang, C.H.
Deposit date:1998-08-17
Release date:1999-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Stabilization of the i-motif by intramolecular adenine-adenine-thymine base triple in the structure of d(ACCCT).
Acta Crystallogr.,Sect.D, 55, 1999
6A1Z
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BU of 6a1z by Molmil
Crystal Structure of dimeric Kinesin-3 KIF13B
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin family member 13B, MAGNESIUM ION
Authors:Ren, J.Q, Wang, S, Feng, W.
Deposit date:2018-06-08
Release date:2018-11-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Coiled-coil 1-mediated fastening of the neck and motor domains for kinesin-3 autoinhibition.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7WHZ
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BU of 7whz by Molmil
SARS-CoV-2 spike protein in complex with three human neutralizing antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ...
Authors:Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S.
Deposit date:2022-01-01
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.
Cell Rep, 39, 2022
6A20
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BU of 6a20 by Molmil
Crystal Structure of auto-inhibited Kinesin-3 KIF13B
Descriptor: ADENOSINE-5'-DIPHOSPHATE, HEXAETHYLENE GLYCOL, Kinesin family member 13B, ...
Authors:Ren, J.Q, Wang, S, Feng, W.
Deposit date:2018-06-08
Release date:2018-11-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Coiled-coil 1-mediated fastening of the neck and motor domains for kinesin-3 autoinhibition.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7WI0
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BU of 7wi0 by Molmil
SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ...
Authors:Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S.
Deposit date:2022-01-01
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.
Cell Rep, 39, 2022
2C5Y
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BU of 2c5y by Molmil
DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN
Descriptor: CELL DIVISION PROTEIN KINASE 2, HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM
Authors:Kontopidis, G, McInnes, C, Pandalaneni, S.R, McNae, I, Gibson, D, Mezna, M, Thomas, M, Wood, G, Wang, S, Walkinshaw, M.D, Fischer, P.M.
Deposit date:2005-11-03
Release date:2006-03-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design.
Chem.Biol., 13, 2006
2C5V
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BU of 2c5v by Molmil
Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design
Descriptor: 4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)-N-[4-(TRIFLUOROMETHYL)PHENYL]PYRIMIDIN-2-AMINE, ALA-ALA-ABA-ARG-SER-LEU-ILE-PFF-NH2, CELL DIVISION PROTEIN KINASE 2, ...
Authors:Kontopidis, G, McInnes, C, Pandalaneni, S.R, McNae, I, Gibson, D, Mezna, M, Thomas, M, Wood, G, Wang, S, Walkinshaw, M.D, Fischer, P.M.
Deposit date:2005-11-02
Release date:2006-03-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design.
Chem.Biol., 13, 2006
2C5O
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BU of 2c5o by Molmil
Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design
Descriptor: 4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)PYRIMIDIN-2-AMINE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2
Authors:Kontopidis, G, McInnes, C, Pandalaneni, S.R, McNae, I, Gibson, D, Mezna, M, Thomas, M, Wood, G, Wang, S, Walkinshaw, M.D, Fischer, P.M.
Deposit date:2005-10-30
Release date:2006-03-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design.
Chem.Biol., 13, 2006
2C5X
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BU of 2c5x by Molmil
Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM
Authors:Kontopidis, G, Mcinnes, C, Pandalaneni, S.R, Mcnae, I, Gibson, D, Mezna, M, Thomas, M, Wood, G, Wang, S, Walkinshaw, M.D, Fischer, P.M.
Deposit date:2005-11-03
Release date:2006-03-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design.
Chem.Biol., 13, 2006
2C5N
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BU of 2c5n by Molmil
Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design
Descriptor: CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE
Authors:Kontopidis, G, McInnes, C, Pandalaneni, S.R, McNae, I, Gibson, D, Mezna, M, Thomas, M, Wood, G, Wang, S, Walkinshaw, M.D, Fischer, P.M.
Deposit date:2005-10-30
Release date:2006-03-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Differential Binding of Inhibitors to Active and Inactive Cdk2 Provides Insights for Drug Design.
Chem.Biol., 13, 2006
2K6Z
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BU of 2k6z by Molmil
Solution structures of copper loaded form PCuA (trans conformation of the peptide bond involving the nitrogen of P14)
Descriptor: COPPER (I) ION, Putative uncharacterized protein TTHA1943
Authors:Abriata, L.A, Banci, L, Bertini, I, Ciofi-Baffoni, S, Gkazonis, P.A, Spyroulias, G.A, Vila, A.J, Wang, S.
Deposit date:2008-07-28
Release date:2008-09-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Mechanism of Cu(A) assembly.
Nat.Chem.Biol., 4, 2008
3N99
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BU of 3n99 by Molmil
Crystal structure of TM1086
Descriptor: CHLORIDE ION, uncharacterized protein TM1086
Authors:Chruszcz, M, Domagalski, M.J, Wang, S, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-05-28
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of TM1086
To be Published
2K70
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BU of 2k70 by Molmil
Solution structures of copper loaded form PCuA (cis conformation of the peptide bond involving the nitrogen of P14)
Descriptor: COPPER (I) ION, Putative uncharacterized protein TTHA1943
Authors:Abriata, L.A, Banci, L, Bertini, I, Ciofi-Baffoni, S, Gkazonis, P.A, Spyroulias, G.A, Vila, A.J, Wang, S.
Deposit date:2008-07-29
Release date:2008-09-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Mechanism of Cu(A) assembly.
Nat.Chem.Biol., 4, 2008
2K6W
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BU of 2k6w by Molmil
Solution structures of apo PCuA (trans conformation of the peptide bond involving the nitrogen of P14)
Descriptor: Putative uncharacterized protein TTHA1943
Authors:Abriata, L.A, Banci, L, Bertini, I, Ciofi-Baffoni, S, Gkazonis, P, Spyroulias, G.A, Vila, A.J, Wang, S.
Deposit date:2008-07-28
Release date:2008-09-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Mechanism of Cu(A) assembly.
Nat.Chem.Biol., 4, 2008
2K6V
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BU of 2k6v by Molmil
Solution structures of apo Sco1 protein from Thermus Thermophilus
Descriptor: Putative cytochrome c oxidase assembly protein
Authors:Abriata, L.A, Banci, L, Bertini, I, Ciofi-Baffoni, S, Gkazonis, P, Spyroulias, G.A, Vila, A.J, Wang, S.
Deposit date:2008-07-28
Release date:2008-09-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Mechanism of Cu(A) assembly.
Nat.Chem.Biol., 4, 2008
2K6Y
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BU of 2k6y by Molmil
Solution structures of apo form PCuA (cis conformation of the peptide bond involving the nitrogen of P14)
Descriptor: Putative uncharacterized protein TTHA1943
Authors:Abriata, L.A, Banci, L, Bertini, I, Ciofi-Baffoni, S, Gkazonis, P, Spyroulias, G.A, Vila, A.J, Wang, S.
Deposit date:2008-07-28
Release date:2008-09-09
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Mechanism of Cu(A) assembly.
Nat.Chem.Biol., 4, 2008
2HRN
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BU of 2hrn by Molmil
Solution Structure of Cu(I) P174L-HSco1
Descriptor: COPPER (I) ION, SCO1 protein homolog, mitochondrial
Authors:Banci, L, Bertini, I, Ciofi-Baffoni, S, Leontari, I, Martinelli, M, Palumaa, P, Sillard, R, Wang, S, Structural Proteomics in Europe (SPINE)
Deposit date:2006-07-20
Release date:2007-01-16
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Human Sco1 functional studies and pathological implications of the P174L mutant.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2HRF
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BU of 2hrf by Molmil
Solution Structure of Cu(I) P174L HSco1
Descriptor: COPPER (I) ION, SCO1 protein homolog, mitochondrial
Authors:Banci, L, Bertini, I, Ciofi-Baffoni, S, Leontari, I, Martinelli, M, Palumaa, P, Sillard, R, Wang, S, Structural Proteomics in Europe (SPINE)
Deposit date:2006-07-20
Release date:2007-01-16
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Human Sco1 functional studies and pathological implications of the P174L mutant.
Proc.Natl.Acad.Sci.Usa, 104, 2007

221051

數據於2024-06-12公開中

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