1C4D
 
 | | GRAMICIDIN CSCL COMPLEX | | 分子名称: | CESIUM ION, CHLORIDE ION, GRAMICIDIN A, ... | | 著者 | Wallace, B.A. | | 登録日 | 1999-06-04 | | 公開日 | 2000-01-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Gramicidin Pore: Crystal Structure of a Cesium Complex.
Science, 241, 1988
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1EDN
 | | HUMAN ENDOTHELIN-1 | | 分子名称: | ENDOTHELIN-1 | | 著者 | Wallace, B.A, Janes, R.W. | | 登録日 | 1994-09-19 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | The crystal structure of human endothelin.
Nat.Struct.Biol., 1, 1994
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1EPP
 | | ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-130,693 (MAS PHE LYS+MTF STA MBA) | | 分子名称: | ENDOTHIAPEPSIN, N-(dimethylsulfamoyl)-L-phenylalanyl-N-[(1S,2S)-2-hydroxy-4-{[(2S)-2-methylbutyl]amino}-1-(2-methylpropyl)-4-oxobutyl]-N~6~-(methylcarbamothioyl)-L-lysinamide, SULFATE ION | | 著者 | Wallace, B.A, Cooper, J.B, Blundell, T.L. | | 登録日 | 1994-07-27 | | 公開日 | 1994-12-20 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors.
J.Med.Chem., 36, 1993
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5HVX
 | | Full length Wild-Type Open-form Sodium Channel NavMs | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DODECAETHYLENE GLYCOL, ... | | 著者 | Sula, A, Booker, J.E, Naylor, C.E, Wallace, B.A. | | 登録日 | 2016-01-28 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The complete structure of an activated open sodium channel.
Nat Commun, 8, 2017
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5HVD
 | | Full length Open-form Sodium Channel NavMs I218C | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Sula, A, Booker, J.E, Naylor, C.E, Wallace, B.A. | | 登録日 | 2016-01-28 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The complete structure of an activated open sodium channel.
Nat Commun, 8, 2017
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4CBC
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4X8A
 | | NavMS pore and C-terminal domain grown from protein purified in LiCl | | 分子名称: | HEGA-10, Ion transport protein, NONAETHYLENE GLYCOL, ... | | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | | 登録日 | 2014-12-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel.
Embo J., 35, 2016
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4X88
 | | E178D Selectivity filter mutant of NavMS voltage-gated pore | | 分子名称: | HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ... | | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | | 登録日 | 2014-12-10 | | 公開日 | 2016-02-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel.
Embo J., 35, 2016
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4X89
 | | NavMs voltage-gated sodium channal pore and C-terminal domain soaked with Silver nitrate | | 分子名称: | HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ... | | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | | 登録日 | 2014-12-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel.
Embo J., 35, 2016
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8S6J
 | | NavMs in complex with riluzole | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine, CHLORIDE ION, ... | | 著者 | Hollingworth, D, Sula, A, Mykhaylyk, V, Wallace, B.A. | | 登録日 | 2024-02-27 | | 公開日 | 2024-09-18 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for the rescue of hyperexcitable cells by the amyotrophic lateral sclerosis drug Riluzole.
Nat Commun, 15, 2024
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5BZB
 | | NavMs voltage-gated sodium channel pore and C-terminal domain | | 分子名称: | DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... | | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | | 登録日 | 2015-06-11 | | 公開日 | 2016-02-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel.
Embo J., 35, 2016
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6SXE
 | | Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with Endoxifen (2.6 Angstrom resolution) | | 分子名称: | 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, Endoxifen, HEGA-10, ... | | 著者 | Sula, A, Hollingworth, D, Wallace, B.A. | | 登録日 | 2019-09-25 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
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6SXF
 | | Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with Tamoxifen (2.8 Angstrom resolution) | | 分子名称: | (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Sula, A, Hollingworth, D, Wallace, B.A. | | 登録日 | 2019-09-25 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.839 Å) | | 主引用文献 | A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
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6SX7
 | | Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) (2.2 Angstrom resolution) | | 分子名称: | 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Sula, A, Hollingworth, D, Wallace, B.A. | | 登録日 | 2019-09-25 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
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6SXG
 | | Crystal Structure of the Voltage-Gated Sodium Channel NavMs in complex with 4-hydroxytamoxifen (2.4 Angstrom resolution) | | 分子名称: | 4-HYDROXYTAMOXIFEN, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Sula, A, Hollingworth, D, Wallace, B.A. | | 登録日 | 2019-09-25 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
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6SX5
 | | Full length Mutant Open-form Sodium Channel NavMs | | 分子名称: | DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... | | 著者 | Sula, A, Hollingworth, D, Wallace, B.A. | | 登録日 | 2019-09-25 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
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6SXC
 | | Crystal structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with 4-hydroxytamoxifen (2.5 Angstrom resolution) | | 分子名称: | 4-HYDROXYTAMOXIFEN, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Sula, A, Hollingworth, D, Wallace, B.A. | | 登録日 | 2019-09-25 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
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6YZ0
 | | Full length Open-form Sodium Channel NavMs F208L in complex with Cannabidiol (CBD) | | 分子名称: | 2-[(1R,2R,5S)-5-methyl-2-(prop-1-en-2-yl)cyclohexyl]-5-pentylbenzene-1,3-diol, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A. | | 登録日 | 2020-05-06 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Cannabidiol interactions with voltage-gated sodium channels.
Elife, 9, 2020
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6YZ2
 | | Full length Open-form Sodium Channel NavMs F208L | | 分子名称: | DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... | | 著者 | Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A. | | 登録日 | 2020-05-06 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Cannabidiol interactions with voltage-gated sodium channels.
Elife, 9, 2020
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6Z8C
 | | Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with N-desmethyltamoxifen (3.2 A resolution) | | 分子名称: | 2-[4-[(~{Z})-1,2-diphenylbut-1-enyl]phenoxy]-~{N}-methyl-ethanamine, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Sula, A, Hollingworth, D, Wallace, B.A. | | 登録日 | 2020-06-02 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
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4KYP
 | | Beta-Scorpion Toxin folded in the periplasm of E.coli | | 分子名称: | Beta-insect excitatory toxin Bj-xtrIT, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL | | 著者 | O'Reilly, A.O, Cole, A.R, Lopes, J.L, Lampert, A, Wallace, B.A. | | 登録日 | 2013-05-29 | | 公開日 | 2014-02-12 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Chaperone-mediated native folding of a beta-scorpion toxin in the periplasm of Escherichia coli.
Biochim.Biophys.Acta, 1840, 2014
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4OXS
 | | Structure of NavMS in complex with channel blocking compound | | 分子名称: | BROMIDE ION, HEGA-10, Ion transport protein, ... | | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | | 登録日 | 2014-02-06 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4P9O
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4PA4
 | | Structure of NavMS in complex with channel blocking compound | | 分子名称: | BROMIDE ION, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | | 登録日 | 2014-04-07 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4PA9
 | | Structure of NavMS in complex with channel blocking compound | | 分子名称: | BROMIDE ION, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | | 登録日 | 2014-04-07 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.43 Å) | | 主引用文献 | Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.
Proc.Natl.Acad.Sci.USA, 111, 2014
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