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PDB: 35 件

6MPS
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BU of 6mps by Molmil
TagT bound to LIIa-WTA
分子名称: 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-mannopyranosyl]-2-deoxy-1-O-[(S)-{[(R)-{[(2Z,6Z,10Z,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-alpha-D-glucopyranose, CHLORIDE ION, MAGNESIUM ION, ...
著者Owens, T.W, Schaefer, K, Kahne, D, Walker, S.
登録日2018-10-08
公開日2018-10-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Substrate Preferences Establish the Order of Cell Wall Assembly in Staphylococcus aureus.
J. Am. Chem. Soc., 140, 2018
3D3H
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Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from Aquifex aeolicus and neryl moenomycin A
分子名称: (2R)-3-{[(S)-{[(2R,3R,4R,5S,6S)-3-{[(2S,3R,4R,5S,6R)-3-(acetylamino)-5-{[(2S,3R,4R,5S,6R)-3-(acetylamino)-5-{[(2R,3R,4S,5R,6S)-6-carbamoyl-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-6-carbamoyl-4-(carbamoyloxy)-5-hydroxy-5-methyltetrahydro-2H-pyran-2-yl]oxy}(hydroxy)phosphoryl]oxy}-2-{[(2Z)-3,7-dimethylocta-2,6-dien-1-yl]oxy}propanoic acid, Penicillin-insensitive transglycosylase
著者Yuan, Y, Sliz, P, Walker, S.
登録日2008-05-11
公開日2008-07-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design.
Acs Chem.Biol., 3, 2008
3PE4
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BU of 3pe4 by Molmil
Structure of human O-GlcNAc transferase and its complex with a peptide substrate
分子名称: Casein kinase II subunit alpha, SULFATE ION, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ...
著者Lazarus, M.B, Nam, Y, Jiang, J, Sliz, P, Walker, S.
登録日2010-10-25
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of human O-GlcNAc transferase and its complex with a peptide substrate.
Nature, 469, 2011
3PE3
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Structure of human O-GlcNAc transferase and its complex with a peptide substrate
分子名称: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-5'-DIPHOSPHATE
著者Lazarus, M.B, Nam, Y, Jiang, J, Sliz, P, Walker, S.
登録日2010-10-25
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Structure of human O-GlcNAc transferase and its complex with a peptide substrate.
Nature, 469, 2011
1KP7
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Conserved RNA Structure within the HCV IRES eIF3 Binding Site
分子名称: Hepatitis C Virus Internal Ribosome Entry Site Fragment
著者Gallego, J, Klinck, R, Collier, A.J, Cole, P.T, Harris, S.J, Harrison, G.P, Aboul-ela, F, Walker, S, Varani, G.
登録日2001-12-29
公開日2002-04-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A conserved RNA structure within the HCV IRES eIF3-binding site.
Nat.Struct.Biol., 9, 2002
3TAX
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BU of 3tax by Molmil
A Neutral Diphosphate Mimic Crosslinks the Active Site of Human O-GlcNAc Transferase
分子名称: Casein kinase II subunit alpha, FORMYL GROUP, SULFATE ION, ...
著者Lazarus, M.B, Jiang, J, Pasquina, L, Sliz, P, Walker, S.
登録日2011-08-04
公開日2011-11-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase.
Nat.Chem.Biol., 8, 2011
4P33
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Crystal structure of E. coli LptB-E163Q in complex with ATP-sodium
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Lipopolysaccharide export system ATP-binding protein LptB, ...
著者Sherman, D.J, Lazarus, M.B, Murphy, L, Liu, C, Walker, S, Ruiz, N, Kahne, D.
登録日2014-03-05
公開日2014-03-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport.
Proc.Natl.Acad.Sci.USA, 111, 2014
4P31
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Crystal structure of a selenomethionine derivative of E. coli LptB in complex with ADP-Magensium
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide export system ATP-binding protein LptB, MAGNESIUM ION
著者Sherman, D.J, Lazarus, M.B, Murphy, L, Liu, C, Walker, S, Ruiz, N, Kahne, D.
登録日2014-03-05
公開日2014-03-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport.
Proc.Natl.Acad.Sci.USA, 111, 2014
4P32
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BU of 4p32 by Molmil
Crystal structure of E. coli LptB in complex with ADP-magnesium
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide export system ATP-binding protein LptB, MAGNESIUM ION
著者Sherman, D.J, Lazarus, M.B, Murphy, L, Liu, C, Walker, S, Ruiz, N, Kahne, D.
登録日2014-03-05
公開日2014-03-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport.
Proc.Natl.Acad.Sci.USA, 111, 2014
2OQO
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BU of 2oqo by Molmil
Crystal structure of a peptidoglycan glycosyltransferase from a class A PBP: insight into bacterial cell wall synthesis
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Penicillin-binding protein 1A (PBP-1a) (PBP1a)
著者Yuan, Y, Sliz, P, Walker, S.
登録日2007-01-31
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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