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PDB: 2 件

5OX5
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BU of 5ox5 by Molmil
HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with CCT6, a GSK1278863-related compound
分子名称: (6-hydroxy-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl)glycine, BICARBONATE ION, Egl nine homolog 1, ...
著者Chowdhury, R, Thinnes, C.C, Schofield, C.J.
登録日2017-09-06
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Chem Sci, 8, 2017
5OP6
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BU of 5op6 by Molmil
Factor Inhibiting HIF (FIH) in complex with zinc and GSK128863
分子名称: 2-[[1,3-dicyclohexyl-4-oxidanyl-2,6-bis(oxidanylidene)pyrimidin-5-yl]carbonylamino]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ...
著者Leissing, T.M, Schofield, C.J, Clifton, I.J, Thinnes, C.C, Lu, X.
登録日2017-08-09
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Chem Sci, 8, 2017

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件を2024-11-06に公開中

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