3DCK
| X-ray structure of D25N chemical analogue of HIV-1 protease complexed with ketomethylene isostere inhibitor | Descriptor: | (2S)-2-{[(2R,5S)-5-{[(2S,3S)-2-{[(2S,3R)-2-(acetylamino)-3-hydroxybutanoyl]amino}-3-methylpentanoyl]amino}-2-butyl-4-oxononanoyl]amino}-N~1~-[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]pentanediamide, Chemical analogue HIV-1 protease | Authors: | Torbeev, V.Y, Mandal, K, Terechko, V.A, Kent, S.B.H. | Deposit date: | 2008-06-03 | Release date: | 2008-08-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of chemically synthesized HIV-1 protease and a ketomethylene isostere inhibitor based on the p2/NC cleavage site Bioorg.Med.Chem.Lett., 18, 2008
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3DCR
| X-ray structure of HIV-1 protease and hydrated form of ketomethylene isostere inhibitor | Descriptor: | Chemical analogue HIV-1 protease, N~2~-[(2R,5S)-5-({(2S,3S)-2-[(N-acetyl-L-threonyl)amino]-3-methylpent-4-enoyl}amino)-2-butyl-4,4-dihydroxynonanoyl]-L-glutaminyl-L-argininamide | Authors: | Torbeev, V.Y, Mandal, K, Terechko, V.A, Kent, S.B.H. | Deposit date: | 2008-06-04 | Release date: | 2008-08-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of chemically synthesized HIV-1 protease and a ketomethylene isostere inhibitor based on the p2/NC cleavage site Bioorg.Med.Chem.Lett., 18, 2008
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