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PDB: 129 件

2FMZ
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BU of 2fmz by Molmil
Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII and XIV with L- and D- phenylalanine, structure with D-Phenylalanine.
分子名称: Carbonic anhydrase 2, D-PHENYLALANINE, MERCURY (II) ION, ...
著者Temperini, C, Scozzafava, A, Vullo, D, Supuran, C.T.
登録日2006-01-10
公開日2006-05-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, VA, VII, and XIV with l- and d-Phenylalanine and Crystallographic Analysis of Their Adducts with Isozyme II: Stereospecific Recognition within the Active Site of an Enzyme and Its Consequences for the Drug Design.
J.Med.Chem., 49, 2006
2GEH
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BU of 2geh by Molmil
N-Hydroxyurea, a versatile zinc binding function in the design of metalloenzyme inhibitors
分子名称: Carbonic anhydrase 2, MERCURY (II) ION, N-HYDROXYUREA, ...
著者Temperini, C, Innocenti, A, Scozzafava, A, Supuran, C.T.
登録日2006-03-20
公開日2006-06-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献N-Hydroxyurea-A versatile zinc binding function in the design of metalloenzyme inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2HL4
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BU of 2hl4 by Molmil
Crystal structure analysis of human carbonic anhydrase II in complex with a benzenesulfonamide derivative
分子名称: CHLORIDE ION, Carbonic anhydrase 2, GLYCEROL, ...
著者Di Fiore, A, Supuran, C.T, Winum, J.-Y, Montero, J.-L, Pedone, C, Scozzafava, A, De Simone, G.
登録日2006-07-06
公開日2007-05-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties
Bioorg.Med.Chem.Lett., 17, 2007
2FMG
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BU of 2fmg by Molmil
Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII and XIV with L- and D- phenylalanine and crystallographic analysis of their adducts with isozyme II: sterospecific recognition within the active site of an enzyme and its consequences for the drug design, structure with L-phenylalanine
分子名称: Carbonic anhydrase 2, MERCURY (II) ION, PHENYLALANINE, ...
著者Temperini, C, Scozzafava, A, Vullo, D, Supuran, C.T.
登録日2006-01-09
公開日2006-05-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, VA, VII, and XIV with l- and d-Phenylalanine and Crystallographic Analysis of Their Adducts with Isozyme II: Stereospecific Recognition within the Active Site of an Enzyme and Its Consequences for the Drug Design.
J.Med.Chem., 49, 2006

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