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PDB: 2 件

5CSW
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BU of 5csw by Molmil
B-RAF in complex with Dabrafenib
分子名称: CHLORIDE ION, Dabrafenib, Serine/threonine-protein kinase B-raf
著者Bader, G, Stadtmuller, H, Steurer, S.
登録日2015-07-23
公開日2016-03-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献A Novel RAF Kinase Inhibitor with DFG-Out-Binding Mode: High Efficacy in BRAF-Mutant Tumor Xenograft Models in the Absence of Normal Tissue Hyperproliferation.
Mol.Cancer Ther., 15, 2016
5CSX
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BU of 5csx by Molmil
CRYSTAL STRUCTURE OF B-RAF IN COMPLEX WITH BI 882370
分子名称: N-(3-{5-[(1-ethylpiperidin-4-yl)(methyl)amino]-3-(pyrimidin-5-yl)-1H-pyrrolo[3,2-b]pyridin-1-yl}-2,4-difluorophenyl)propane-1-sulfonamide, Serine/threonine-protein kinase B-raf, alpha-D-glucopyranose
著者Bader, G, Stadtmuller, H, Steurer, S.
登録日2015-07-23
公開日2016-03-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献A Novel RAF Kinase Inhibitor with DFG-Out-Binding Mode: High Efficacy in BRAF-Mutant Tumor Xenograft Models in the Absence of Normal Tissue Hyperproliferation.
Mol.Cancer Ther., 15, 2016

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件を2024-05-15に公開中

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