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4P7E
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Triazolopyridine compounds as selective JAK1 inhibitors: from hit identification to GLPG0634
Descriptor: N-(5-{4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide, Tyrosine-protein kinase JAK2
Authors:Menet, C.C.J, Fletcher, S, Van Lommen, G, Geney, R, Blanc, J, Smits, K, Jouannigot, N, van der Aar, E.M, Clement-Lacroix, P, Lepescheux, L, Galien, R, Vayssiere, B, Nelles, L, Christophe, T, Brys, R, Uhring, M, Ciesielski, F, Van Rompaey, L.
Deposit date:2014-03-27
Release date:2014-11-19
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634.
J.Med.Chem., 57, 2014

227344

数据于2024-11-13公开中

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