5YMA
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![BU of 5yma by Molmil](/molmil-images/mine/5yma) | |
6EDE
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![BU of 6ede by Molmil](/molmil-images/mine/6ede) | tRNA 2'-phosphotransferase | 分子名称: | Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2018-08-09 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.553 Å) | 主引用文献 | Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation. Nat Commun, 10, 2019
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6E3A
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![BU of 6e3a by Molmil](/molmil-images/mine/6e3a) | tRNA 2'-phosphotransferase | 分子名称: | COENZYME A, Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2018-07-13 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation. Nat Commun, 10, 2019
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6VDD
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![BU of 6vdd by Molmil](/molmil-images/mine/6vdd) | POL domain of Pol1 from M. smegmatis complex with DNA primer-template and dNTP | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A*(DCT))-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
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6VDC
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![BU of 6vdc by Molmil](/molmil-images/mine/6vdc) | POL domain of Pol1 from M. smegmatis | 分子名称: | DNA polymerase I, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
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6VDE
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![BU of 6vde by Molmil](/molmil-images/mine/6vde) | Full-length M. smegmatis Pol1 | 分子名称: | DNA polymerase I, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.713 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
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6NHX
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![BU of 6nhx by Molmil](/molmil-images/mine/6nhx) | mycobacterial DNA ligase D complexed with ATP and MES | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent DNA ligase | 著者 | Shuman, S, Unciuleac, M, Goldgur, Y. | 登録日 | 2018-12-24 | 公開日 | 2019-02-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structures of ATP-bound DNA ligase D in a closed domain conformation reveal a network of amino acid and metal contacts to the ATP phosphates. J. Biol. Chem., 294, 2019
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6TZX
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![BU of 6tzx by Molmil](/molmil-images/mine/6tzx) | Crystal Structure of Fungal RNA Kinase | 分子名称: | INOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, tRNA ligase | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-13 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.529 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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6U05
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![BU of 6u05 by Molmil](/molmil-images/mine/6u05) | Crystal Structure of Fungal RNA Kinase | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-13 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.948 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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6TZO
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![BU of 6tzo by Molmil](/molmil-images/mine/6tzo) | Crystal Structure of Fungal RNA Kinase | 分子名称: | 2'-DEOXYGUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, tRNA ligase | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-12 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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6U03
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![BU of 6u03 by Molmil](/molmil-images/mine/6u03) | Crystal Structure of Fungal RNA Kinase | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA ligase | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-13 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.849 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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6U00
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![BU of 6u00 by Molmil](/molmil-images/mine/6u00) | Crystal Structure of Fungal RNA Kinase | 分子名称: | PHOSPHATE ION, tRNA ligase | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-13 | 公開日 | 2019-11-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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6TZM
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![BU of 6tzm by Molmil](/molmil-images/mine/6tzm) | Crystal Structure of Fungal RNA Kinase | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, tRNA ligase | 著者 | Shuman, S, Goldgur, Y, Banerjee, A. | 登録日 | 2019-08-12 | 公開日 | 2019-11-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.714 Å) | 主引用文献 | Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res., 47, 2019
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6NHZ
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6C36
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![BU of 6c36 by Molmil](/molmil-images/mine/6c36) | Mycobacterium smegmatis flap endonuclease mutant D208N | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION, PHOSPHATE ION | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | 登録日 | 2018-01-09 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities. Nucleic Acids Res., 46, 2018
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6C35
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![BU of 6c35 by Molmil](/molmil-images/mine/6c35) | Mycobacterium smegmatis flap endonuclease mutant D148N | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | 登録日 | 2018-01-09 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities. Nucleic Acids Res., 46, 2018
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6C34
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![BU of 6c34 by Molmil](/molmil-images/mine/6c34) | Mycobacterium smegmatis DNA flap endonuclease mutant D125N | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | 登録日 | 2018-01-09 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities. Nucleic Acids Res., 46, 2018
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6C33
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![BU of 6c33 by Molmil](/molmil-images/mine/6c33) | Mycobacterium smegmatis DNA flap endonuclease | 分子名称: | 5'-3' exonuclease, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Carl, A, Uson, M.L. | 登録日 | 2018-01-09 | 公開日 | 2018-03-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities. Nucleic Acids Res., 46, 2018
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3KGD
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![BU of 3kgd by Molmil](/molmil-images/mine/3kgd) | Crystal structure of E. coli RNA 3' cyclase | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCEROL, RNA 3'-terminal phosphate cyclase, ... | 著者 | Shuman, S, Tanaka, N, Smith, P. | 登録日 | 2009-10-28 | 公開日 | 2010-04-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structure of the RNA 3'-phosphate cyclase-adenylate intermediate illuminates nucleotide specificity and covalent nucleotidyl transfer. Structure, 18, 2010
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5U32
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![BU of 5u32 by Molmil](/molmil-images/mine/5u32) | |
5UJ0
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![BU of 5uj0 by Molmil](/molmil-images/mine/5uj0) | |
3N9D
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![BU of 3n9d by Molmil](/molmil-images/mine/3n9d) | Monoclinic Structure of P. aeruginosa LigD phosphoesterase domain | 分子名称: | MANGANESE (II) ION, Probable ATP-dependent DNA ligase, SULFATE ION, ... | 著者 | Shuman, S, Nair, P, Smith, P. | 登録日 | 2010-05-28 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily Proc.Natl.Acad.Sci.USA, 107, 2010
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2OWO
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![BU of 2owo by Molmil](/molmil-images/mine/2owo) | Last Stop on the Road to Repair: Structure of E.coli DNA Ligase Bound to Nicked DNA-Adenylate | 分子名称: | 26-MER, 5'-D(*AP*CP*AP*AP*TP*TP*GP*CP*GP*AP*CP*(OMC)P*C)-3', 5'-D(*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*AP*TP*G)-3', ... | 著者 | Shuman, S, Nandakumar, J, Nair, P.A. | 登録日 | 2007-02-16 | 公開日 | 2007-05-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Last Stop on the Road to Repair: Structure of E. coli DNA Ligase Bound to Nicked DNA-Adenylate. Mol.Cell, 26, 2007
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3N9B
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![BU of 3n9b by Molmil](/molmil-images/mine/3n9b) | Crystal Structure of the P. aeruginosa LigD phosphoesterase domain | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | 著者 | Shuman, S, Nair, P, Smith, P. | 登録日 | 2010-05-28 | 公開日 | 2010-08-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structure of bacterial LigD 3'-phosphoesterase unveils a DNA repair superfamily Proc.Natl.Acad.Sci.USA, 107, 2010
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2QY2
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![BU of 2qy2 by Molmil](/molmil-images/mine/2qy2) | |