7XN1
 
 | | Crystal structure of human acetylcholinesterase in complex with tacrine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Acetylcholinesterase, ... | | 著者 | Dileep, K.V, Ihara, K, Mishima-Tsumagari, C, Kukimoto-Niino, M, Yonemochi, M, Hanada, K, Shirouzu, M, Zhang, K.Y.J. | | 登録日 | 2022-04-27 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery
Int.J.Biol.Macromol., 210, 2022
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3UG1
 | | Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in the apo form | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor | | 著者 | Parker, L.J, Handa, N, Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | | 登録日 | 2011-11-02 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor
Oncogene, 32, 2013
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3VA2
 | | Crystal structure of human Interleukin-5 in complex with its alpha receptor | | 分子名称: | Interleukin-5, Interleukin-5 receptor subunit alpha | | 著者 | Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. | | 登録日 | 2011-12-28 | | 公開日 | 2012-07-25 | | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | | 主引用文献 | Structural basis of interleukin-5 dimer recognition by its alpha receptor
Protein Sci., 21, 2012
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3VJN
 | | Crystal structure of the mutated EGFR kinase domain (G719S/T790M) in complex with AMPPNP. | | 分子名称: | Epidermal growth factor receptor, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Yoshikawa, S, Kukimoto-Niino, M, Shirouzu, M, Semba, K, Yamamoto, T, Yokoyama, S. | | 登録日 | 2011-10-27 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor.
Oncogene, 32, 2013
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1X42
 | | Crystal structure of a haloacid dehalogenase family protein (PH0459) from Pyrococcus horikoshii OT3 | | 分子名称: | hypothetical protein PH0459 | | 著者 | Arai, R, Kukimoto-Niino, M, Sugahara, M, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-12 | | 公開日 | 2005-11-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the probable haloacid dehalogenase PH0459 from Pyrococcus horikoshii OT3
Protein Sci., 15, 2006
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1UDX
 | | Crystal structure of the conserved protein TT1381 from Thermus thermophilus HB8 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, the GTP-binding protein Obg | | 著者 | Kukimoto-Niino, M, Shirouzu, M, Murayama, K, Inoue, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-05-07 | | 公開日 | 2004-03-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Crystal structure of the GTP-binding protein Obg from Thermus thermophilus HB8.
J.Mol.Biol., 337, 2004
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1UGO
 | | Solution structure of the first Murine BAG domain of Bcl2-associated athanogene 5 | | 分子名称: | Bcl2-associated athanogene 5 | | 著者 | Endoh, H, Hayashi, F, Seimiya, K, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-06-17 | | 公開日 | 2004-08-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange
Structure, 18, 2010
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1UG2
 | | Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain | | 分子名称: | 2610100B20Rik gene product | | 著者 | Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-06-11 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain
To be Published
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1WI6
 | | Solution structure of the RNA binding domain from mouse hypothetical protein BAB23670 | | 分子名称: | Hypothetical protein (RIKEN cDNA 1300006N24) | | 著者 | Suzuki, S, Muto, Y, Nagata, T, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-05-28 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the RNA binding domain from mouse hypothetical protein BAB23670
To be Published
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1WI5
 | | Solution structure of the S1 RNA binding domain from human hypothetical protein BAA11502 | | 分子名称: | RRP5 protein homolog | | 著者 | Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-05-28 | | 公開日 | 2004-11-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the S1 RNA binding domain from human hypothetical protein BAA11502
To be Published
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7VGV
 | | Anion free form of light-driven chloride ion-pumping rhodopsin, NM-R3, structure determined by serial femtosecond crystallography at SACLA | | 分子名称: | CHLORIDE ION, Chloride pumping rhodopsin, HEXADECANE, ... | | 著者 | Hosaka, T, Nango, E, Nakane, T, Luo, F, Kimura-Someya, T, Shirouzu, M. | | 登録日 | 2021-09-18 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7VGU
 | | Time-resolved serial femtosecond crystallography structure of light-driven chloride ion-pumping rhodopsin, NM-R3 : structure obtained 1 msec after photoexcitation with bromide ion | | 分子名称: | BROMIDE ION, Chloride pumping rhodopsin, DECANE, ... | | 著者 | Hosaka, T, Nango, E, Nakane, T, Luo, F, Kimura-Someya, T, Shirouzu, M. | | 登録日 | 2021-09-18 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7VGT
 | | Time-resolved serial femtosecond crystallography structure of light-driven chloride ion-pumping rhodopsin, NM-R3: resting state structure with bromide ion | | 分子名称: | BROMIDE ION, Chloride pumping rhodopsin, DECANE, ... | | 著者 | Hosaka, T, Nango, E, Nakane, T, Luo, F, Kimura-Someya, T, Shirouzu, M. | | 登録日 | 2021-09-18 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1WIB
 | | Solution structure of the N-terminal domain from mouse hypothetical protein BAB22488 | | 分子名称: | 60S ribosomal protein L12 | | 著者 | Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-05-28 | | 公開日 | 2004-11-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the N-terminal domain from mouse hypothetical protein BAB22488
To be Published
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7CPJ
 | | ycbZ-stalled 70S ribosome | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shirouzu, M, Ito, T. | | 登録日 | 2020-08-07 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | The landscape of translational stall sites in bacteria revealed by monosome and disome profiling.
Rna, 28, 2022
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7DDQ
 | | Structure of RC-LH1-PufX from Rhodobacter veldkampii | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Antenna pigment protein alpha chain, Antenna pigment protein beta chain, ... | | 著者 | Bracun, L, Yamagata, A, Shirouzu, M, Liu, L.N. | | 登録日 | 2020-10-29 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Cryo-EM structure of the photosynthetic RC-LH1-PufX supercomplex at 2.8-angstrom resolution.
Sci Adv, 7, 2021
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3WU5
 | | Reduced E.coli Lon Proteolytic domain | | 分子名称: | Lon protease, SULFATE ION | | 著者 | Nishii, W, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Muramatsu, T, Yokoyama, S. | | 登録日 | 2014-04-22 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.
Nat. Chem. Biol., 11, 2015
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3WU3
 | | Reduced-form structure of E.coli Lon Proteolytic domain | | 分子名称: | Lon protease, SULFATE ION | | 著者 | Nishii, W, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Muramatsu, T, Yokoyama, S. | | 登録日 | 2014-04-22 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.
Nat. Chem. Biol., 11, 2015
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7EG2
 | | Crystal structure of the apoAequorin complex with (S)-daCTZ | | 分子名称: | (2~{S})-2-(hydroxymethyl)-6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-4-(phenylmethyl)-3~{H}-inden-1-one, Aequorin-2 | | 著者 | Tomabechi, Y, Shirouzu, M. | | 登録日 | 2021-03-24 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Chiral deaza-coelenterazine analogs for probing a substrate-binding site in the Ca2+-binding photoprotein aequorin.
Plos One, 16, 2021
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7EG3
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3WU4
 | | Oxidized-form structure of E.coli Lon Proteolytic domain | | 分子名称: | Lon protease, SULFATE ION | | 著者 | Nishii, W, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Muramatsu, T, Yokoyama, S. | | 登録日 | 2014-04-22 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.
Nat. Chem. Biol., 11, 2015
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1ZRJ
 | | Solution structure of the SAP domain of human E1B-55kDa-associated protein 5 isoform c | | 分子名称: | E1B-55kDa-associated protein 5 isoform c | | 著者 | Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-19 | | 公開日 | 2005-11-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the SAP domain of human E1B-55kDa-associated protein 5 isoform c
To be Published
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3WU6
 | | Oxidized E.coli Lon Proteolytic domain | | 分子名称: | Lon protease, SULFATE ION | | 著者 | Nishii, W, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Muramatsu, T, Yokoyama, S. | | 登録日 | 2014-04-22 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.
Nat. Chem. Biol., 11, 2015
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7C3G
 | | Crystal structure of human ALK2 kinase domain with R206H mutation in complex with a bicyclic pyrazole inhibitor RK-73134 | | 分子名称: | 1,2-ETHANEDIOL, Activin receptor type-1, SULFATE ION, ... | | 著者 | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | | 登録日 | 2020-05-12 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Novel bicyclic pyrazoles as potent ALK2 (R206H) inhibitors for the treatment of fibrodysplasia ossificans progressiva.
Bioorg.Med.Chem.Lett., 38, 2021
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7VSX
 | | Crystal structure of QL-nanoKAZ (Reverse mutant of nanoKAZ with L18Q and V27L) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, QLnK | | 著者 | Tomabechi, Y, Sekine, S, Shirouzu, M, Takamitsu, H, Satoshi, I. | | 登録日 | 2021-10-27 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Reverse mutants of the catalytic 19 kDa mutant protein (nanoKAZ/nanoLuc) from Oplophorus luciferase with coelenterazine as preferred substrate.
Plos One, 17, 2022
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