6BNQ
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6BNP
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6BNW
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6BNV
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7UDT
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![BU of 7udt by Molmil](/molmil-images/mine/7udt) | cryo-EM structure of the rigor state wild type myosin-15-F-actin complex (symmetry expansion and re-centering) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Gong, R, Reynolds, M.J, Alushin, G.M. | 登録日 | 2022-03-20 | 公開日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia. Sci Adv, 8, 2022
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7UDU
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![BU of 7udu by Molmil](/molmil-images/mine/7udu) | cryo-EM structure of the ADP state wild type myosin-15-F-actin complex (symmetry expansion and re-centering) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Gong, R, Reynolds, M.J, Alushin, G.M. | 登録日 | 2022-03-20 | 公開日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | 主引用文献 | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia. Sci Adv, 8, 2022
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7R94
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![BU of 7r94 by Molmil](/molmil-images/mine/7r94) | T-Plastin-F-actin complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Mei, L, Alushin, G.M. | 登録日 | 2021-06-28 | 公開日 | 2022-07-06 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural mechanism for bidirectional actin cross-linking by T-plastin. Proc.Natl.Acad.Sci.USA, 119, 2022
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7SX8
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![BU of 7sx8 by Molmil](/molmil-images/mine/7sx8) | T-Plastin-F-actin complex, parallel bundled state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Mei, L, Reynolds, M.J, Alushin, G.M. | 登録日 | 2021-11-22 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Structural mechanism for bidirectional actin cross-linking by T-plastin. Proc.Natl.Acad.Sci.USA, 119, 2022
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7SX9
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![BU of 7sx9 by Molmil](/molmil-images/mine/7sx9) | T-Plastin-F-actin complex, anti-parallel bundled state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Mei, L, Reynolds, M.J, Alushin, G.M. | 登録日 | 2021-11-22 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Structural mechanism for bidirectional actin cross-linking by T-plastin. Proc.Natl.Acad.Sci.USA, 119, 2022
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6BNU
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7SXA
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![BU of 7sxa by Molmil](/molmil-images/mine/7sxa) | T-Plastin-F-actin complex, pre-bundling intermediate state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Mei, L, Reynolds, M.J, Alushin, G.M. | 登録日 | 2021-11-22 | 公開日 | 2022-08-31 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (6.87 Å) | 主引用文献 | Structural mechanism for bidirectional actin cross-linking by T-plastin. Proc.Natl.Acad.Sci.USA, 119, 2022
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3JBI
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![BU of 3jbi by Molmil](/molmil-images/mine/3jbi) | MDFF model of the vinculin tail domain bound to F-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M. | 登録日 | 2015-09-02 | 公開日 | 2015-11-04 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | 主引用文献 | The Structural Basis of Actin Organization by Vinculin and Metavinculin. J.Mol.Biol., 428, 2016
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3JBK
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![BU of 3jbk by Molmil](/molmil-images/mine/3jbk) | Cryo-EM reconstruction of the metavinculin-actin interface | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M. | 登録日 | 2015-09-03 | 公開日 | 2015-11-04 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | 主引用文献 | The Structural Basis of Actin Organization by Vinculin and Metavinculin. J.Mol.Biol., 428, 2016
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5DG6
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![BU of 5dg6 by Molmil](/molmil-images/mine/5dg6) | 2.35A resolution structure of Norovirus 3CL protease in complex an oxadiazole-based, cell permeable macrocyclic (21-mer) inhibitor | 分子名称: | 3C-LIKE PROTEASE, CHLORIDE ION, tert-butyl [(4S,7S,10S)-7-(cyclohexylmethyl)-10-(hydroxymethyl)-5,8,13-trioxo-23-oxa-6,9,14,21,22-pentaazabicyclo[18.2.1]tricosa-1(22),20-dien-4-yl]carbamate | 著者 | Lovell, S, Battaile, K.P, Mehzabeen, N, Damalanka, V.C, Kim, Y, Alliston, K.R, Weerawarna, P.M, Kankanamalage, A.C.G, Lushington, G.H, Chang, K.-O, Groutas, W.C. | 登録日 | 2015-08-27 | 公開日 | 2016-02-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease. J.Med.Chem., 59, 2016
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1MI4
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![BU of 1mi4 by Molmil](/molmil-images/mine/1mi4) | Glyphosate insensitive G96A mutant EPSP synthase liganded with shikimate-3-phosphate | 分子名称: | 5-enolpyruvylshikimate-3-phosphate synthase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE | 著者 | Eschenburg, S, Healy, M.L, Priestman, M.A, Lushington, G.H, Schonbrunn, E. | 登録日 | 2002-08-21 | 公開日 | 2002-12-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | How the mutation glycine96 to alanine confers glyphosate insensitivity to 5-enolpyruvyl
shikimate-3-phosphate synthase from Escherichia coli. PLANTA, 216, 2002
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5DGJ
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![BU of 5dgj by Molmil](/molmil-images/mine/5dgj) | 1.0A resolution structure of Norovirus 3CL protease in complex an oxadiazole-based, cell permeable macrocyclic (20-mer) inhibitor | 分子名称: | 3C-LIKE PROTEASE, tert-butyl [(4S,7S,10S)-7-(cyclohexylmethyl)-10-(hydroxymethyl)-5,8,13-trioxo-22-oxa-6,9,14,20,21-pentaazabicyclo[17.2.1]docosa-1(21),19-dien-4-yl]carbamate | 著者 | Lovell, S, Battaile, K.P, Mehzabeen, N, Damalanka, V.C, Kim, Y, Alliston, K.R, Weerawarna, P.M, Kankanamalage, A.C.G, Lushington, G.H, Chang, K.-O, Groutas, W.C. | 登録日 | 2015-08-27 | 公開日 | 2016-02-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease. J.Med.Chem., 59, 2016
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5E0G
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![BU of 5e0g by Molmil](/molmil-images/mine/5e0g) | 1.20 A resolution structure of Norovirus 3CL protease in complex with a triazole-based macrocyclic (17-mer) inhibitor | 分子名称: | (phenylmethyl) ~{N}-[(8~{S},11~{S},14~{S})-8-(hydroxymethyl)-11-(2-methylpropyl)-5,10,13-tris(oxidanylidene)-1,4,9,12,17,18-hexazabicyclo[14.2.1]nonadeca-16(19),17-dien-14-yl]carbamate, CHLORIDE ION, Norovirus 3C-like protease | 著者 | Lovell, S, Battaile, K.P, Mehzabeen, N, Weerawarna, P.M, Kim, Y, Kankanamalage, A.C.G, Damalanka, V.C, Lushington, G.H, Alliston, K.R, Chang, K.-O, Groutas, W.C. | 登録日 | 2015-09-28 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies. Eur.J.Med.Chem., 119, 2016
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5E0H
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![BU of 5e0h by Molmil](/molmil-images/mine/5e0h) | 1.95 A resolution structure of Norovirus 3CL protease in complex with a triazole-based macrocyclic (18-mer) inhibitor | 分子名称: | (phenylmethyl) ~{N}-[(9~{S},12~{S},15~{S})-9-(hydroxymethyl)-12-(2-methylpropyl)-6,11,14-tris(oxidanylidene)-1,5,10,13,18,19-hexazabicyclo[15.2.1]icosa-17(20),18-dien-15-yl]carbamate, GLYCEROL, Norovirus 3C-like protease | 著者 | Lovell, S, Battaile, K.P, Mehzabeen, N, Weerawarna, P.M, Kim, Y, Kankanamalage, A.C.G, Damalanka, V.C, Lushington, G.H, Alliston, K.R, Chang, K.-O, Groutas, W.C. | 登録日 | 2015-09-28 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies. Eur.J.Med.Chem., 119, 2016
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5E0J
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![BU of 5e0j by Molmil](/molmil-images/mine/5e0j) | 1.20 A resolution structure of Norovirus 3CL protease in complex with a triazole-based macrocyclic (21-mer) inhibitor | 分子名称: | (phenylmethyl) ~{N}-[(12~{S},15~{S},18~{S})-15-(cyclohexylmethyl)-12-(hydroxymethyl)-9,14,17-tris(oxidanylidene)-1,8,13,16,21,22-hexazabicyclo[18.2.1]tricosa-20(23),21-dien-18-yl]carbamate, CHLORIDE ION, Norovirus 3C-like protease | 著者 | Lovell, S, Battaile, K.P, Mehzabeen, N, Weerawarna, P.M, Kim, Y, Kankanamalage, A.C.G, Damalanka, V.C, Lushington, G.H, Alliston, K.R, Chang, K.-O, Groutas, W.C. | 登録日 | 2015-09-28 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies. Eur.J.Med.Chem., 119, 2016
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3JBJ
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![BU of 3jbj by Molmil](/molmil-images/mine/3jbj) | Cryo-EM reconstruction of F-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Kim, L.Y, Thompson, P.M, Lee, H.T, Pershad, M, Campbell, S.L, Alushin, G.M. | 登録日 | 2015-09-03 | 公開日 | 2015-11-04 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | 主引用文献 | The Structural Basis of Actin Organization by Vinculin and Metavinculin. J.Mol.Biol., 428, 2016
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