3UFL
| Discovery of Pyrrolidine-based b-Secretase Inhibitors: Lead Advancement through Conformational Design for Maintenance of Ligand Binding Efficiency | 分子名称: | (1R,4'S)-3,4-dihydro-2H-spiro[naphthalene-1,3'-pyrrolidin]-4'-yl[(2S,4R)-2,4-diphenylpiperidin-1-yl]methanone, Beta-secretase 1, GLYCEROL, ... | 著者 | Allison, T, Munshi, S, Soisson, S.M. | 登録日 | 2011-11-01 | 公開日 | 2012-01-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of pyrrolidine-based beta-secretase inhibitors: Lead advancement through conformational design for maintenance of ligand binding efficiency. Bioorg.Med.Chem.Lett., 22, 2012
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3WE0
| L-Amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid oxidase/monooxygenase | 著者 | Im, D.H, Matsui, D, Fukuta, Y, Fushinobu, S, Isobe, K, Asano, Y. | 登録日 | 2013-06-26 | 公開日 | 2014-02-12 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mutational and crystallographic analysis of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813: Interconversion between oxidase and monooxygenase activities FEBS Open Bio, 4, 2014
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3WH6
| Crystal structure of GH1 beta-glucosidase Td2F2 glucose complex | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SODIUM ION, alpha-D-glucopyranose, ... | 著者 | Jo, T, Fushinobu, S, Uchiyama, T, Yaoi, K. | 登録日 | 2013-08-21 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure and identification of a key amino acid for glucose tolerance, substrate specificity, and transglycosylation activity of metagenomic beta-glucosidase Td2F2. Febs J., 283, 2016
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3WH5
| Crystal structure of GH1 beta-glucosidase Td2F2 | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, SODIUM ION, ... | 著者 | Jo, T, Fushinobu, S, Uchiyama, T, Yaoi, K. | 登録日 | 2013-08-21 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure and identification of a key amino acid for glucose tolerance, substrate specificity, and transglycosylation activity of metagenomic beta-glucosidase Td2F2. Febs J., 283, 2016
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3WBD
| Crystal structure of anti-polysialic acid antibody single chain Fv fragment (mAb735) complexed with octasialic acid | 分子名称: | CITRATE ANION, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, single chain Fv fragment of mAb735 | 著者 | Nagae, M, Ikeda, A, Hanashima, S, Kitajima, K, Sato, C, Yamaguchi, Y. | 登録日 | 2013-05-14 | 公開日 | 2013-10-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of anti-polysialic acid antibody single chain Fv fragment complexed with octasialic acid: insight into the binding preference for polysialic acid. J.Biol.Chem., 288, 2013
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3WH7
| Crystal structure of GH1 beta-glucosidase Td2F2 L-fucose complex | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, SODIUM ION, beta-D-fucopyranose, ... | 著者 | Jo, T, Fushinobu, S, Uchiyama, T, Yaoi, K. | 登録日 | 2013-08-21 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Crystal structure and identification of a key amino acid for glucose tolerance, substrate specificity, and transglycosylation activity of metagenomic beta-glucosidase Td2F2. Febs J., 283, 2016
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5XQJ
| Crystal structure of a PL 26 exo-rhamnogalacturonan lyase from Penicillium chrysogenum complexed with unsaturated galacturonosyl rhamnose substituted with galactose | 分子名称: | 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-2)-[beta-D-galactopyranose-(1-4)]alpha-L-rhamnopyranose, 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-2)-alpha-L-rhamnopyranose, CALCIUM ION, ... | 著者 | Kunishige, Y, Iwai, M, Tada, T, Nishimura, S, Sakamoto, T. | 登録日 | 2017-06-07 | 公開日 | 2018-04-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal structure of exo-rhamnogalacturonan lyase from Penicillium chrysogenum as a member of polysaccharide lyase family 26 FEBS Lett., 592, 2018
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3WH8
| Crystal structure of GH1 beta-glucosidase Td2F2 isofagomine complex | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, GLYCEROL, ... | 著者 | Jo, T, Fushinobu, S, Uchiyama, T, Yaoi, K. | 登録日 | 2013-08-21 | 公開日 | 2014-09-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure and identification of a key amino acid for glucose tolerance, substrate specificity, and transglycosylation activity of metagenomic beta-glucosidase Td2F2. Febs J., 283, 2016
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5XQ3
| Crystal structure of a PL 26 exo-rhamnogalacturonan lyase from Penicillium chrysogenum | 分子名称: | CALCIUM ION, Pcrglx protein | 著者 | Kunishige, Y, Iwai, M, Tada, T, Nishimura, S, Sakamoto, T. | 登録日 | 2017-06-06 | 公開日 | 2018-03-21 | 最終更新日 | 2018-05-16 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structure of exo-rhamnogalacturonan lyase from Penicillium chrysogenum as a member of polysaccharide lyase family 26 FEBS Lett., 592, 2018
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3ZIH
| Bacillus subtilis SepF, C-terminal domain | 分子名称: | CELL DIVISION PROTEIN SEPF | 著者 | Duman, R.E, Ishikawa, S, Celik, I, Ogasawara, N, Lowe, J, Hamoen, L.W. | 登録日 | 2013-01-09 | 公開日 | 2013-11-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and Genetic Analyses Reveal the Protein Sepf as a New Membrane Anchor for the Z Ring. Proc.Natl.Acad.Sci.USA, 110, 2013
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3ZIG
| SepF-like protein from Pyrococcus furiosus | 分子名称: | SEPF-LIKE PROTEIN | 著者 | Duman, R, Ishikawa, S, Celik, I, Ogasawara, N, Lowe, J, Hamoen, L.W. | 登録日 | 2013-01-09 | 公開日 | 2013-11-27 | 最終更新日 | 2013-12-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Genetic Analyses Reveal the Protein Sepf as a New Membrane Anchor for the Z Ring. Proc.Natl.Acad.Sci.USA, 110, 2013
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3ZIE
| SepF-like protein from Archaeoglobus fulgidus | 分子名称: | SEPF-LIKE PROTEIN | 著者 | Duman, R, Ishikawa, S, Celik, I, Ogasawara, N, Lowe, J, Hamoen, L.W. | 登録日 | 2013-01-08 | 公開日 | 2013-11-20 | 最終更新日 | 2013-12-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and Genetic Analyses Reveal the Protein Sepf as a New Membrane Anchor for the Z Ring Proc.Natl.Acad.Sci.USA, 110, 2013
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5YY2
| Crystal structure of AsqI with Zn | 分子名称: | Uncharacterized protein AsqI, ZINC ION | 著者 | Hara, K, Hashimoto, H, Kishimoto, S, Watanabe, K. | 登録日 | 2017-12-07 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Enzymatic one-step ring contraction for quinolone biosynthesis. Nat Commun, 9, 2018
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5YY3
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3ZII
| Bacillus subtilis SepF G109K, C-terminal domain | 分子名称: | CELL DIVISION PROTEIN SEPF | 著者 | Duman, R, Ishikawa, S, Celik, I, Ogasawara, N, Lowe, J, Hamoen, L.W. | 登録日 | 2013-01-09 | 公開日 | 2013-11-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and Genetic Analyses Reveal the Protein Sepf as a New Membrane Anchor for the Z Ring. Proc.Natl.Acad.Sci.USA, 110, 2013
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3VYK
| Crystal structure of C-type lectin domain of murine dendritic cell inhibitory receptor 2 in complex with N-glycan | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)][2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]methyl alpha-D-mannopyranoside, C-type lectin domain family 4, ... | 著者 | Nagae, M, Yamanaka, K, Hanashima, S, Ikeda, A, Satoh, T, Matsumoto, N, Yamamoto, K, Yamaguchi, Y. | 登録日 | 2012-09-26 | 公開日 | 2013-10-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Recognition of Bisecting N-Acetylglucosamine: STRUCTURAL BASIS FOR ASYMMETRIC INTERACTION WITH THE MOUSE LECTIN DENDRITIC CELL INHIBITORY RECEPTOR 2 J.Biol.Chem., 288, 2013
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2KUQ
| Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK | 分子名称: | Fibroblast growth factor receptor substrate 3,LINKER,ALK tyrosine kinase receptor | 著者 | Li, H, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2010-02-24 | 公開日 | 2010-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2 J.Struct.Funct.Genom., 11, 2010
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5ODI
| Heterodisulfide reductase / [NiFe]-hydrogenase complex from Methanothermococcus thermolithotrophicus cocrystallized with CoM-SH | 分子名称: | 1-THIOETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ... | 著者 | Wagner, T, Koch, J, Ermler, U, Shima, S. | 登録日 | 2017-07-05 | 公開日 | 2017-08-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Methanogenic heterodisulfide reductase (HdrABC-MvhAGD) uses two noncubane [4Fe-4S] clusters for reduction. Science, 357, 2017
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5O4H
| HcgC from Methanococcus maripaludis cocrystallized with SAM and pyridinol | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ACETATE ION, HcgC, ... | 著者 | Wagner, T, Bai, L, Xu, T, Hu, X, Ermler, U, Shima, S. | 登録日 | 2017-05-29 | 公開日 | 2017-07-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC. Angew. Chem. Int. Ed. Engl., 56, 2017
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5ODH
| Heterodisulfide reductase / [NiFe]-hydrogenase complex from Methanothermococcus thermolithotrophicus soaked with heterodisulfide for 3.5 minutes | 分子名称: | 1-THIOETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ... | 著者 | Wagner, T, Koch, J, Ermler, U, Shima, S. | 登録日 | 2017-07-05 | 公開日 | 2017-08-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Methanogenic heterodisulfide reductase (HdrABC-MvhAGD) uses two noncubane [4Fe-4S] clusters for reduction. Science, 357, 2017
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5O4M
| Fresh crystals of HcgC from Methanococcus maripaludis cocrystallized with SAH and pyridinol | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 6-carboxy methyl-4-hydroxy-2-pyridinol, DIMETHYL SULFOXIDE, ... | 著者 | Wagner, T, Bai, L, Xu, T, Hu, X, Ermler, U, Shima, S. | 登録日 | 2017-05-29 | 公開日 | 2017-07-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC. Angew. Chem. Int. Ed. Engl., 56, 2017
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5O4N
| Apo HcgC from Methanococcus maripaludis soaked with SAH and pyridinol | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 6-carboxy methyl-4-hydroxy-2-pyridinol, DIMETHYL SULFOXIDE, ... | 著者 | Wagner, T, Bai, L, Xu, T, Hu, X, Ermler, U, Shima, S. | 登録日 | 2017-05-29 | 公開日 | 2017-07-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC. Angew. Chem. Int. Ed. Engl., 56, 2017
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5ODQ
| Heterodisulfide reductase / [NiFe]-hydrogenase complex from Methanothermococcus thermolithotrophicus soaked with bromoethanesulfonate. | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-bromanylethanesulfonic acid, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ... | 著者 | Wagner, T, Koch, J, Ermler, U, Shima, S. | 登録日 | 2017-07-06 | 公開日 | 2017-08-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Methanogenic heterodisulfide reductase (HdrABC-MvhAGD) uses two noncubane [4Fe-4S] clusters for reduction. Science, 357, 2017
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5ODC
| Heterodisulfide reductase / [NiFe]-hydrogenase complex from Methanothermococcus thermolithotrophicus at 2.3 A resolution | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ACETATE ION, ... | 著者 | Wagner, T, Koch, J, Ermler, U, Shima, S. | 登録日 | 2017-07-05 | 公開日 | 2017-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Methanogenic heterodisulfide reductase (HdrABC-MvhAGD) uses two noncubane [4Fe-4S] clusters for reduction. Science, 357, 2017
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5YJI
| Co-crystal structure of Mouse Nicotinamide N-methyltransferase (NNMT) with small molecule analog of Nicotinamide | 分子名称: | 6-methoxy-1-methyl-2H-pyridine-3-carboxamide, Nicotinamide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Birudukota, S, Swaminathan, S, Thakur, M.K, Parveen, R, Kandan, S, Hallur, M.S, Rajagopal, S, Ruf, S, Dhakshinamoorthy, S, Kannt, A, Gosu, R. | 登録日 | 2017-10-10 | 公開日 | 2018-03-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. Sci Rep, 8, 2018
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