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PDB: 69 件

8X5K
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The Crystal Structure of SYK from Biortus.
分子名称: 1,2-ETHANEDIOL, 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide, Tyrosine-protein kinase SYK
著者Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z.
登録日2023-11-17
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of SYK from Biortus.
To Be Published
8WFQ
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The Crystal Structure of RALDH1 from Biortus.
分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Aldehyde dehydrogenase 1A1
著者Wang, F, Cheng, W, Lv, Z, Qi, J, Shen, Z.
登録日2023-09-20
公開日2023-11-22
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The Crystal Structure of RALDH1 from Biortus.
To Be Published
8XU4
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The Crystal Structure of MAPK2 from Biortus.
分子名称: MALONIC ACID, MAP kinase-activated protein kinase 2
著者Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z.
登録日2024-01-12
公開日2024-01-24
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The Crystal Structure of MAPK2 from Biortus.
To Be Published
8XPX
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BU of 8xpx by Molmil
The Crystal Structure of PARP12 from Biortus.
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Wang, F, Cheng, W, Lv, Z, Qi, J, Shen, Z.
登録日2024-01-04
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The Crystal Structure of PARP12 from Biortus.
To Be Published
8XI7
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The Crystal Structure of UCHL1 from Biortus.
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase isozyme L1
著者Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z.
登録日2023-12-19
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Crystal Structure of UCHL1 from Biortus.
To Be Published
8YHI
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BU of 8yhi by Molmil
The Crystal Structure of SHP1 from Biortus.
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 6
著者Wang, F, Cheng, W, Yuan, Z, Qi, J, Shen, Z.
登録日2024-02-28
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The Crystal Structure of SHP1 from Biortus.
To Be Published
4XQD
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BU of 4xqd by Molmil
X-ray structure analysis of xylanase-WT at pH4.0
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endo-1,4-beta-xylanase 2, IODIDE ION
著者Wan, Q, Park, J.M, Riccardi, D.M, Hanson, L.B, Fisher, Z, Smith, J.C, Ostermann, A, Schrader, T, Graham, D.E, Coates, L, Langan, P, Kovalevsky, A.Y.
登録日2015-01-19
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XQW
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X-ray structure analysis of xylanase-N44E with MES at pH6.0
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Endo-1,4-beta-xylanase 2, IODIDE ION
著者Wan, Q, Park, J.M, Riccardi, D.M, Hanson, L.B, Fisher, Z, Smith, J.C, Ostermann, A, Schrader, T, Graham, D.E, Coates, L, Langan, P, Kovalevsky, A.Y.
登録日2015-01-20
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XPV
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Neutron and X-ray structure analysis of xylanase: N44D at pH6
分子名称: Endo-1,4-beta-xylanase 2, IODIDE ION
著者Wan, Q, Park, J.M, Riccardi, D.M, Hanson, L.B, Fisher, Z, Smith, J.C, Ostermann, A, Schrader, T, Graham, D.E, Coates, L, Langan, P, Kovalevsky, A.Y.
登録日2015-01-18
公開日2015-09-30
最終更新日2023-09-27
実験手法NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION
主引用文献Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XQ4
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BU of 4xq4 by Molmil
X-ray structure analysis of xylanase - N44D
分子名称: Endo-1,4-beta-xylanase 2, IODIDE ION
著者Wan, Q, Park, J.M, Riccardi, D.M, Hanson, L.B, Fisher, Z, Smith, J.C, Ostermann, A, Schrader, T, Graham, D.E, Coates, L, Langan, P, Kovalevsky, A.Y.
登録日2015-01-19
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography.
Proc.Natl.Acad.Sci.USA, 112, 2015
7JKY
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BU of 7jky by Molmil
Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-126
分子名称: Bromodomain-containing protein 4, N-(1-[1,1-di(pyridin-2-yl)ethyl]-6-{1-methyl-6-oxo-5-[(piperidin-4-yl)amino]-1,6-dihydropyridin-3-yl}-1H-indol-4-yl)ethanesulfonamide, SODIUM ION
著者Ratia, K.M, Xiong, R, Li, Y, Shen, Z, Zhao, J, Huang, F, Dubrovyskyii, O, Thatcher, G.R.
登録日2020-07-29
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib.
J.Med.Chem., 63, 2020
7JKZ
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Bromodomain-containing protein 4 (BRD4) bromodomain 2 (BD2) complexed with YF3-126
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, GLYCEROL, ...
著者Ratia, K.M, Xiong, R, Li, Y, Shen, Z, Zhao, J, Huang, F, Dubrovyskyii, O, Thatcher, G.R.
登録日2020-07-29
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib.
J.Med.Chem., 63, 2020
7JKW
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Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with ZN1-99
分子名称: Bromodomain-containing protein 4, N-(6-{5-[(azetidin-3-yl)amino]-1-methyl-6-oxo-1,6-dihydropyridin-3-yl}-1-[1,1-di(pyridin-2-yl)ethyl]-1H-indol-4-yl)ethanesulfonamide
著者Ratia, K.M, Xiong, R, Li, Y, Shen, Z, Zhao, J, Huang, F, Dubrovyskyii, O, Thatcher, G.R.
登録日2020-07-29
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib.
J.Med.Chem., 63, 2020
7JKX
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BU of 7jkx by Molmil
Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6
分子名称: Bromodomain-containing protein 4, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-[1-methyl-5-(methylamino)-6-oxo-1,6-dihydropyridin-3-yl]-1H-indol-4-yl}ethanesulfonamide
著者Ratia, K.M, Xiong, R, Li, Y, Shen, Z, Zhao, J, Huang, F, Dubrovyskyii, O, Thatcher, G.R.
登録日2020-07-29
公開日2021-06-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6
To Be Published
7KYQ
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Crystal structure of human BCCIP beta (Native1)
分子名称: BRCA2 and CDKN1A-interacting protein
著者Choi, W.S, Liu, B, Shen, Z, Yang, W.
登録日2020-12-08
公開日2021-06-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Structure of human BCCIP and implications for binding and modification of partner proteins.
Protein Sci., 30, 2021
7KYS
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Crystal structure of human BCCIP beta (Native2)
分子名称: 1,2-ETHANEDIOL, BRCA2 and CDKN1A-interacting protein, DI(HYDROXYETHYL)ETHER
著者Choi, W.S, Liu, B, Shen, Z, Yang, W.
登録日2020-12-08
公開日2021-06-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human BCCIP and implications for binding and modification of partner proteins.
Protein Sci., 30, 2021
7E9V
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BU of 7e9v by Molmil
The Crystal Structure of human UMP-CMP kinase from Biortus.
分子名称: SULFATE ION, UMP-CMP kinase
著者Wang, F, Lin, D, Wang, R, Wei, X, Shen, Z, Wang, M.
登録日2021-03-05
公開日2021-03-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Crystal Structure of human UMP-CMP kinase from Biortus.
To Be Published
3QPS
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BU of 3qps by Molmil
Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni
分子名称: CHOLIC ACID, CmeR
著者Lei, H.T, Routh, M.D, Shen, Z, Su, C.C, Zhang, Q, Yu, E.W.
登録日2011-02-14
公開日2011-03-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni.
Protein Sci., 20, 2011
3QQA
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Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni
分子名称: CmeR, TAUROCHOLIC ACID
著者Lei, H.T, Routh, M.D, Shen, Z, Su, C.-C, Zhang, Q, Yu, E.W.
登録日2011-02-15
公開日2011-03-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of CmeR-bile acid complexes from Campylobacter jejuni.
Protein Sci., 20, 2011
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