8V1R
 
 | | Herpes simplex virus 1 polymerase holoenzyme bound to DNA and DTTP in closed conformation | | Descriptor: | DNA polymerase, DNA polymerase processivity factor, MAGNESIUM ION, ... | | Authors: | Pan, J, Abraham, J, Coen, D.M, Shankar, S, Yang, P, Hogle, J. | | Deposit date: | 2023-11-21 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Viral DNA polymerase structures reveal mechanisms for drug selectivity
Cell(Cambridge,Mass.), 2024
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8V1Q
 | | Herpes simplex virus 1 polymerase holoenzyme bound to DNA in both open/closed conformations | | Descriptor: | DNA polymerase, DNA polymerase processivity factor, MAGNESIUM ION, ... | | Authors: | Pan, J, Abraham, J, Coen, D.M, Shankar, S, Yang, P, Hogle, J. | | Deposit date: | 2023-11-21 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Viral DNA polymerase structures reveal mechanisms for drug selectivity
Cell(Cambridge,Mass.), 2024
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8V1T
 | | Herpes simplex virus 1 polymerase holoenzyme bound to DNA and acyclovir triphosphate in closed conformation | | Descriptor: | ACYCLOVIR TRIPHOSPHATE, DNA polymerase, DNA polymerase processivity factor, ... | | Authors: | Pan, J, Abraham, J, Coen, D.M, Shankar, S, Yang, P, Hogle, J. | | Deposit date: | 2023-11-21 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Viral DNA polymerase structures reveal mechanisms for drug selectivity
Cell(Cambridge,Mass.), 2024
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2WWB
 | | CRYO-EM STRUCTURE OF THE MAMMALIAN SEC61 COMPLEX BOUND TO THE ACTIVELY TRANSLATING WHEAT GERM 80S RIBOSOME | | Descriptor: | 25S RRNA, 5.8S RRNA, 60S RIBOSOMAL PROTEIN L17-A, ... | | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | | Deposit date: | 2009-10-22 | | Release date: | 2009-12-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.48 Å) | | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Science, 326, 2009
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2WW9
 | | Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome | | Descriptor: | 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... | | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | | Deposit date: | 2009-10-22 | | Release date: | 2009-12-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.6 Å) | | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Science, 326, 2009
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2WWA
 | | Cryo-EM structure of idle yeast Ssh1 complex bound to the yeast 80S ribosome | | Descriptor: | 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... | | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | | Deposit date: | 2009-10-22 | | Release date: | 2009-12-08 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (8.9 Å) | | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
Science, 326, 2009
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6AHO
 | | Crystal structure of Kap114p | | Descriptor: | Importin subunit beta-5 | | Authors: | Liao, C.C, Shankar, S, Ahmed, G.R, Hsia, K.C. | | Deposit date: | 2018-08-20 | | Release date: | 2019-10-23 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Karyopherin Kap114p-mediated trans-repression controls ribosomal gene expression under saline stress.
Embo Rep., 21, 2020
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1T60
 | | Crystal structure of Type IV collagen NC1 domain from bovine lens capsule | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, POTASSIUM ION, ... | | Authors: | Vanacore, R.M, Shanmugasundararaj, S, Friedman, D.B, Bondar, O, Hudson, B.G, Sundaramoorthy, M. | | Deposit date: | 2004-05-05 | | Release date: | 2004-09-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links
J.Biol.Chem., 279, 2004
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1T61
 | | crystal structure of collagen IV NC1 domain from placenta basement membrane | | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Vanacore, R.M, Shanmugasundararaj, S, Friedman, D.B, Bondar, O, Hudson, B.G, Sundaramoorthy, M. | | Deposit date: | 2004-05-05 | | Release date: | 2004-09-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links
J.Biol.Chem., 279, 2004
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6EJW
 | | Tryptophan Repressor TrpR from E.coli wildtype with Indole-3-acetic acid as ligand | | Descriptor: | 1H-INDOL-3-YLACETIC ACID, Trp operon repressor | | Authors: | Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. | | Deposit date: | 2017-09-23 | | Release date: | 2019-02-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | A biosensor for the direct visualization of auxin
Nature, 2021
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6ELB
 | | Tryptophan Repressor TrpR from E.coli variant M42F T44L T81M N87G S88Y with Indole-3-acetic acid as ligand | | Descriptor: | 1H-INDOL-3-YLACETIC ACID, Trp operon repressor | | Authors: | Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. | | Deposit date: | 2017-09-28 | | Release date: | 2019-02-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.437 Å) | | Cite: | A biosensor for the direct visualization of auxin
Nature, 2021
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6ENI
 | | Tryptophan Repressor TrpR from E.coli variant T44L S88Y with Indole-3-acetic acid as ligand | | Descriptor: | 1,2-ETHANEDIOL, 1H-INDOL-3-YLACETIC ACID, Trp operon repressor | | Authors: | Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. | | Deposit date: | 2017-10-04 | | Release date: | 2019-02-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | A biosensor for the direct visualization of auxin
Nature, 2021
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6ELG
 | | Tryptophan Repressor TrpR from E.coli variant M42F T44L T81I S88Y with Indole-3-acetonitrile | | Descriptor: | 1H-indol-3-ylacetonitrile, Trp operon repressor | | Authors: | Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. | | Deposit date: | 2017-09-28 | | Release date: | 2019-02-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | A biosensor for the direct visualization of auxin
Nature, 2021
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6EJZ
 | | Tryptophan Repressor TrpR from E.coli variant S88Y with Indole-3-acetic acid as ligand | | Descriptor: | 1,2-ETHANEDIOL, 1H-INDOL-3-YLACETIC ACID, SULFATE ION, ... | | Authors: | Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. | | Deposit date: | 2017-09-24 | | Release date: | 2019-02-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A biosensor for the direct visualization of auxin
Nature, 2021
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6ELF
 | | Tryptophan Repressor TrpR from E.coli variant M42F T44L T81I S88Y with Indole-3-acetic acid as ligand | | Descriptor: | 1H-INDOL-3-YLACETIC ACID, Trp operon repressor | | Authors: | Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. | | Deposit date: | 2017-09-28 | | Release date: | 2019-02-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.832 Å) | | Cite: | A biosensor for the direct visualization of auxin
Nature, 2021
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6EKP
 | | Tryptophan Repressor TrpR from E.coli variant T44L T81M S88Y with Indole-3-acetic acid as ligand | | Descriptor: | 1H-INDOL-3-YLACETIC ACID, 3,6,9,12,15-PENTAOXAHEPTADECANE, Trp operon repressor | | Authors: | Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. | | Deposit date: | 2017-09-26 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.46 Å) | | Cite: | A biosensor for the direct visualization of auxin
Nature, 2021
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6FAL
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6F7F
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6F7G
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6F9K
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5A9Z
 | | Complex of Thermous thermophilus ribosome bound to BipA-GDPCP | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Kumar, V, Chen, Y, Ahmed, T, Tan, J, Ero, R, Bhushan, S, Gao, Y.-G. | | Deposit date: | 2015-07-23 | | Release date: | 2015-10-14 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5AA0
 | | Complex of Thermous thermophilus ribosome (A-and P-site tRNA) bound to BipA-GDPCP | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | | Authors: | Kumar, V, Chen, Y, Ahmed, T, Tan, J, Ero, R, Bhushan, S, Gao, Y.-G. | | Deposit date: | 2015-07-23 | | Release date: | 2015-10-14 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
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6ENN
 | | Tryptophan Repressor TrpR from E.coli variant T44L T81M N87G S88Y with Indole-3-acetic acid as ligand | | Descriptor: | 1H-INDOL-3-YLACETIC ACID, Trp operon repressor | | Authors: | Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. | | Deposit date: | 2017-10-05 | | Release date: | 2019-02-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.17 Å) | | Cite: | A biosensor for the direct visualization of auxin
Nature, 2021
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