1RMD
| RAG1 DIMERIZATION DOMAIN | Descriptor: | RAG1, ZINC ION | Authors: | Bellon, S.F, Rodgers, K.K, Schatz, D.G, Coleman, J.E, Steitz, T.A. | Deposit date: | 1997-01-10 | Release date: | 1997-07-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster. Nat.Struct.Biol., 4, 1997
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3GNB
| Crystal structure of the RAG1 nonamer-binding domain with DNA | Descriptor: | 5'-D(*AP*AP*TP*TP*TP*TP*CP*AP*GP*AP*AP*AP*CP*C)-3', 5'-D(*AP*GP*GP*TP*TP*TP*CP*TP*GP*AP*AP*AP*AP*C)-3', V(D)J recombination-activating protein 1 | Authors: | Yin, F.F, Bailey, S, Innis, C.A, Steitz, T.A, Schatz, D.G. | Deposit date: | 2009-03-16 | Release date: | 2009-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis. Nat.Struct.Mol.Biol., 16, 2009
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3GNA
| Crystal structure of the RAG1 nonamer-binding domain with DNA | Descriptor: | 5'-D(*AP*CP*TP*TP*AP*AP*CP*AP*AP*AP*AP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*TP*TP*TP*TP*GP*TP*TP*AP*AP*G)-3', V(D)J recombination-activating protein 1 | Authors: | Yin, F.F, Bailey, S, Innis, C.A, Steitz, T.A, Schatz, D.G. | Deposit date: | 2009-03-16 | Release date: | 2009-04-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis. Nat.Struct.Mol.Biol., 16, 2009
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6B40
| BbRAGL-3'TIR synaptic complex with nicked DNA refined with C2 symmetry | Descriptor: | 31TIR intact strand, 31TIR pre-nicked strand of flanking DNA, 31TIR pre-nicked strand of signal DNA, ... | Authors: | Zhang, Y, Cheng, T.C, Xiong, Y, Schatz, D.G. | Deposit date: | 2017-09-25 | Release date: | 2019-03-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Transposon molecular domestication and the evolution of the RAG recombinase. Nature, 569, 2019
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6XNZ
| Structure of RAG1 (R848M/E649V)-RAG2-DNA Target Capture Complex | Descriptor: | 12RSS integration strand (34-mer), 12RSS non-integration strand (34-mer), 23RSS integration strand (45-mer), ... | Authors: | Zhang, Y, Corbett, E, Wu, S, Schatz, D.G. | Deposit date: | 2020-07-05 | Release date: | 2020-08-26 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase. Embo J., 39, 2020
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6PQY
| Cryo-EM structure of HzTransib/TIR DNA transposon end complex (TEC) | Descriptor: | DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*CP*GP*AP*TP*CP*CP*AP*CP*CP*GP*TP*G)-3'), Putative DNA-mediated transposase | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-10 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6PR5
| Cryo-EM structure of HzTransib strand transfer complex (STC) | Descriptor: | DNA (30-MER), DNA (39-MER), DNA (5'-D(*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*TP*CP*A)-3'), ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-10 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6PQN
| Crystal structure of HzTransib transposase | Descriptor: | GLYCEROL, PHOSPHATE ION, Putative DNA-mediated transposase, ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-09 | Release date: | 2019-10-09 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6PQU
| Cryo-EM structure of HzTransib/nicked TIR substrate DNA pre-reaction complex (PRC) | Descriptor: | DNA (5'-D(P*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*T)-3'), DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA-mediated transposase, ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-10 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6PQX
| Cryo-EM structure of HzTransib/nicked TIR substrate DNA hairpin forming complex (HFC) | Descriptor: | CALCIUM ION, DNA (5'-D(P*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*T)-3'), ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-10 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6PQR
| Cryo-EM structure of HzTransib/intact TIR substrate DNA pre-reaction complex (PRC) | Descriptor: | DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*TP*CP*AP*CP*GP*GP*TP*GP*GP*AP*TP*CP*GP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*CP*GP*AP*TP*CP*CP*AP*CP*CP*GP*TP*GP*AP*GP*AP*TP*CP*TP*AP*G)-3'), DNA-mediated transposase, ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-09 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6XNY
| Structure of RAG1 (R848M/E649V)-RAG2-DNA Strand Transfer Complex (Paired-Form) | Descriptor: | 12RSS integration strand (55-mer), 12RSS signal DNA top strand (34-mer), 23RSS integration strand (66-mer), ... | Authors: | Zhang, Y, Corbett, E, Wu, S, Schatz, D.G. | Deposit date: | 2020-07-05 | Release date: | 2020-08-26 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase. Embo J., 39, 2020
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6XNX
| Structure of RAG1 (R848M/E649V)-RAG2-DNA Strand Transfer Complex (Dynamic-Form) | Descriptor: | 12RSS integration strand DNA (55-MER), 12RSS signal top strand DNA (34-MER), 23RSS integration strand DNA (66-MER), ... | Authors: | Zhang, Y, Corbett, E, Wu, S, Schatz, D.G. | Deposit date: | 2020-07-05 | Release date: | 2020-08-26 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase. Embo J., 39, 2020
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