1MDZ
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![BU of 1mdz by Molmil](/molmil-images/mine/1mdz) | Crystal structure of ArnB aminotransferase with cycloserine and pyridoxal 5' phosphate | 分子名称: | ArnB aminotransferase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, PYRIDOXAL-5'-PHOSPHATE | 著者 | Noland, B.W, Newman, J.M, Hendle, J, Badger, J, Christopher, J.A, Tresser, J, Buchanan, M.D, Wright, T, Rutter, M.E, Sanderson, W.E, Muller-Dieckmann, H.-J, Gajiwala, K.S, Sauder, J.M, Buchanan, S.G. | 登録日 | 2002-08-07 | 公開日 | 2002-12-11 | 最終更新日 | 2018-12-26 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: A 4-amino-4-deoxy-L-arabinose lipopolysaccharide modifying enzyme Structure, 10, 2002
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1MDX
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![BU of 1mdx by Molmil](/molmil-images/mine/1mdx) | Crystal structure of ArnB transferase with pyridoxal 5' phosphate | 分子名称: | 2-OXOGLUTARIC ACID, ArnB aminotransferase, GLYCEROL, ... | 著者 | Noland, B.W, Newman, J.M, Hendle, J, Badger, J, Christopher, J.A, Tresser, J, Buchanan, M.D, Wright, T.A, Rutter, M.E, Sanderson, W.E, Muller-Dieckmann, H.-J, Gajiwala, K.S, Sauder, J.M, Buchanan, S.G. | 登録日 | 2002-08-07 | 公開日 | 2002-12-11 | 最終更新日 | 2018-12-26 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: A 4-amino-4-deoxy-L-arabinose lipopolysaccharide modifying enzyme Structure, 10, 2002
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4BBX
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![BU of 4bbx by Molmil](/molmil-images/mine/4bbx) | Discovery of a potent, selective and orally active PDE10A inhibitor for the treatment of schizophrenia | 分子名称: | 4-[3-[1-[(2S)-2-methoxypropyl]pyrazol-4-yl]-2-methyl-imidazo[1,2-a]pyrazin-8-yl]morpholine, CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE 10A, ... | 著者 | Bartolome-Nebreda, J.M, Conde-Ceide, S, Delgado, F, Martin, M.L, Martinez-Viturro, C.M, Pastor, J, Tong, H.M, Iturrino, L, Macdonald, G.J, Sanderson, W, Megens, A, Langlois, X, Somers, M, Vanhoof, G. | 登録日 | 2012-09-28 | 公開日 | 2013-10-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of a Potent, Selective and Orally Active Pde10A Inhibitor for the Potential Treatment of Schizophrenia. J.Med.Chem., 57, 2014
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4D08
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![BU of 4d08 by Molmil](/molmil-images/mine/4d08) | PDE2a catalytic domain in complex with a brain penetrant inhibitor | 分子名称: | 1-(5-butoxypyridin-3-yl)-4-methyl-8-(morpholin-4-ylmethyl)[1,2,4]triazolo[4,3-a]quinoxaline, CGMP-DEPENDENT 3', 5'-CYCLIC PHOSPHODIESTERASE, ... | 著者 | Buijnsters, P, Andres, J.I, DeAngelis, M, Langlois, X, Rombouts, F, Sanderson, W, Tresadern, G, Trabanco, A, VanHoof, G, VanRoosbroeck, Y. | 登録日 | 2014-04-24 | 公開日 | 2014-08-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-Based Design of a Potent, Selective, and Brain Penetrating Pde2 Inhibitor with Demonstrated Target Engagement. Acs Med.Chem.Lett., 5, 2014
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4D09
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![BU of 4d09 by Molmil](/molmil-images/mine/4d09) | PDE2a catalytic domain in complex with a brain penetrant inhibitor | 分子名称: | CGMP-DEPENDENT 3', 5'-CYCLIC PHOSPHODIESTERASE, MAGNESIUM ION, ... | 著者 | Buijnsters, P, Andres, J.I, DeAngelis, M, Langlois, X, Rombouts, F, Sanderson, W, Tresadern, G, Trabanco, A, VanHoof, G, VanRoosbroeck, Y. | 登録日 | 2014-04-24 | 公開日 | 2014-08-06 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-Based Design of a Potent, Selective, and Brain Penetrating Pde2 Inhibitor with Demonstrated Target Engagement. Acs Med.Chem.Lett., 5, 2014
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1MDO
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![BU of 1mdo by Molmil](/molmil-images/mine/1mdo) | Crystal structure of ArnB aminotransferase with pyridomine 5' phosphate | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ArnB aminotransferase | 著者 | Noland, B.W, Newman, J.M, Hendle, J, Badger, J, Christopher, J.A, Tresser, J, Buchanan, M.D, Wright, T, Rutter, M.E, Sanderson, W.E, Muller-Dieckmann, H.-J, Gajiwala, K, Sauder, J.M, Buchanan, S.G. | 登録日 | 2002-08-07 | 公開日 | 2002-12-11 | 最終更新日 | 2018-12-26 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: A 4-amino-4-deoxy-L-arabinose lipopolysaccharide modifying enzyme Structure, 10, 2002
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1INN
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![BU of 1inn by Molmil](/molmil-images/mine/1inn) | CRYSTAL STRUCTURE OF D. RADIODURANS LUXS, P21 | 分子名称: | AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, METHIONINE, ZINC ION | 著者 | Lewis, H.A, Furlong, E.B, Bergseid, M.G, Sanderson, W.E, Buchanan, S.G. | 登録日 | 2001-05-14 | 公開日 | 2001-06-08 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs. Structure, 9, 2001
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1J6V
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![BU of 1j6v by Molmil](/molmil-images/mine/1j6v) | CRYSTAL STRUCTURE OF D. RADIODURANS LUXS, C2 | 分子名称: | AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, ZINC ION | 著者 | Lewis, H.A, Furlong, E.B, Bergseid, M.G, Sanderson, W.E, Buchanan, S.G. | 登録日 | 2001-05-14 | 公開日 | 2001-06-08 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs. Structure, 9, 2001
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1J6X
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![BU of 1j6x by Molmil](/molmil-images/mine/1j6x) | CRYSTAL STRUCTURE OF HELICOBACTER PYLORI LUXS | 分子名称: | AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, METHIONINE, ZINC ION | 著者 | Lewis, H.A, Furlong, E.B, Bergseid, M.G, Sanderson, W.E, Buchanan, S.G. | 登録日 | 2001-05-14 | 公開日 | 2001-06-08 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs. Structure, 9, 2001
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1J6W
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![BU of 1j6w by Molmil](/molmil-images/mine/1j6w) | CRYSTAL STRUCTURE OF HAEMOPHILUS INFLUENZAE LUXS | 分子名称: | AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, METHIONINE, ZINC ION | 著者 | Lewis, H.A, Furlong, E.B, Bergseid, M.G, Sanderson, W.E, Buchanan, S.G. | 登録日 | 2001-05-14 | 公開日 | 2001-06-08 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs. Structure, 9, 2001
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