2LHE
 
 | | Gb98-T25I,L20A | | Descriptor: | Gb98 | | Authors: | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | Deposit date: | 2011-08-08 | | Release date: | 2012-02-29 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
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1SUC
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1SUD
 | | CALCIUM-INDEPENDENT SUBTILISIN BY DESIGN | | Descriptor: | ACETONE, CALCIUM ION, POTASSIUM ION, ... | | Authors: | Gallagher, T, Bryan, P, Gilliland, G.L. | | Deposit date: | 1992-06-10 | | Release date: | 1994-01-31 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Calcium-independent subtilisin by design.
Proteins, 16, 1993
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2KDL
 | | NMR structures of GA95 and GB95, two designed proteins with 95% sequence identity but different folds and functions | | Descriptor: | designed protein | | Authors: | He, Y, Alexander, P, Chen, Y, Bryan, P, Orban, J. | | Deposit date: | 2009-01-12 | | Release date: | 2009-12-29 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | A minimal sequence code for switching protein structure and function.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2KDM
 | | NMR structures of GA95 and GB95, two designed proteins with 95% sequence identity but different folds and functions | | Descriptor: | DESIGNED PROTEIN | | Authors: | He, Y, Alexander, P, Chen, Y, Bryan, P, Orban, J. | | Deposit date: | 2009-01-12 | | Release date: | 2009-12-29 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | From the Cover: A minimal sequence code for switching protein structure and function.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3CO0
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1ZXH
 | | G311 mutant protein | | Descriptor: | Immunoglobulin G binding protein G | | Authors: | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | | Deposit date: | 2005-06-08 | | Release date: | 2005-11-08 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds.
Biochemistry, 44, 2005
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2JWU
 | | Solution NMR structures of two designed proteins with 88% sequence identity but different fold and function | | Descriptor: | Gb88 | | Authors: | He, Y, Chen, Y, Alexander, P, Bryan, P, Orban, J. | | Deposit date: | 2007-10-25 | | Release date: | 2008-09-09 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BGO
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3CNQ
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1ZXG
 | | Solution structure of A219 | | Descriptor: | Immunoglobulin G binding protein A | | Authors: | He, Y, Yeh, D.C, Alexander, P, Bryan, P.N, Orban, J. | | Deposit date: | 2005-06-08 | | Release date: | 2005-11-08 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds.
Biochemistry, 44, 2005
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2FS1
 | | solution structure of PSD-1 | | Descriptor: | PSD-1 | | Authors: | He, Y, Rozak, D.A, Sari, N, Chen, Y, Bryan, P, Orban, J. | | Deposit date: | 2006-01-20 | | Release date: | 2006-12-05 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure, dynamics, and stability variation in bacterial albumin binding modules: implications for species specificity.
Biochemistry, 45, 2006
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3F49
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4DDC
 | | EVAL processed HEWL, cisplatin DMSO NAG silicone oil | | Descriptor: | Cisplatin, DIMETHYL SULFOXIDE, Lysozyme C | | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | | Deposit date: | 2012-01-18 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein.
Acta Crystallogr.,Sect.D, 68, 2012
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4DD7
 | | EVAL processed HEWL, carboplatin DMSO glycerol | | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, Lysozyme C, ... | | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | | Deposit date: | 2012-01-18 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein.
Acta Crystallogr.,Sect.D, 68, 2012
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4DD9
 | | EVAL processed HEWL, carboplatin DMSO paratone | | Descriptor: | DIMETHYL SULFOXIDE, Lysozyme C, carboplatin | | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | | Deposit date: | 2012-01-18 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein.
Acta Crystallogr.,Sect.D, 68, 2012
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2MH8
 | | GA-79-MBP cs-rosetta structures | | Descriptor: | GA-79-MBP, maltose binding protein | | Authors: | He, Y, Chen, Y, Porter, L, Bryan, P, Orban, J. | | Deposit date: | 2013-11-19 | | Release date: | 2015-04-08 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Subdomain interactions foster the design of two protein pairs with 80% sequence identity but different folds.
Biophys.J., 108, 2015
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1KN6
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2LU1
 | | pfsub2 solution NMR structure | | Descriptor: | Subtilase | | Authors: | He, Y, Chen, Y, Ruan, B, O'Brochta, D, Bryan, P, Orban, J. | | Deposit date: | 2012-06-06 | | Release date: | 2012-10-03 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum.
Proteins, 80, 2012
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2XTH
 | | K2PtBr6 binding to lysozyme | | Descriptor: | HEXABROMOPLATINATE(IV), LYSOZYME C | | Authors: | Helliwell, J.R, Bell, A.M.T, Bryant, P, Fisher, S, Habash, J, Helliwell, M, Margiolaki, I, Kaenket, S, Watier, Y, Wright, J, Yalamanchili, S.K. | | Deposit date: | 2010-10-07 | | Release date: | 2010-12-08 | | Last modified: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Time-Dependent Analysis of K2Ptbr6 Binding to Lysozyme Studied by Protein Powder and Single Crystal X-Ray Analysis
Z.Kristallogr., 225, 2010
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4DDA
 | | EVAL processed HEWL, NAG | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme C | | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | | Deposit date: | 2012-01-18 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein.
Acta Crystallogr.,Sect.D, 68, 2012
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4DD1
 | | EVAL processed HEWL, cisplatin aqueous paratone | | Descriptor: | 2-methylprop-1-ene, Lysozyme C | | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | | Deposit date: | 2012-01-18 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein.
Acta Crystallogr.,Sect.D, 68, 2012
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4DD2
 | | EVAL processed HEWL, carboplatin aqueous glycerol | | Descriptor: | GLYCEROL, Lysozyme C | | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | | Deposit date: | 2012-01-18 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein.
Acta Crystallogr.,Sect.D, 68, 2012
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4DD3
 | | EVAL processed HEWL, carboplatin aqueous paratone | | Descriptor: | 2-methylprop-1-ene, CHLORIDE ION, Lysozyme C | | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | | Deposit date: | 2012-01-18 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein.
Acta Crystallogr.,Sect.D, 68, 2012
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4DD0
 | | EVAL processed HEWL, cisplatin aqueous glycerol | | Descriptor: | GLYCEROL, Lysozyme C | | Authors: | Tanley, S.W, Schreurs, A.M, Kroon-Batenburg, L.M, Meredith, J, Prendergast, R, Walsh, D, Bryant, P, Levy, C, Helliwell, J.R. | | Deposit date: | 2012-01-18 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural studies of the effect that dimethyl sulfoxide (DMSO) has on cisplatin and carboplatin binding to histidine in a protein.
Acta Crystallogr.,Sect.D, 68, 2012
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