7AD1
 
 | | Cryo-EM structure of a prefusion stabilized SARS-CoV-2 Spike (D614N, R682S, R685G, A892P, A942P and V987P)(One up trimer) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Envelope glycoprotein,Spike glycoprotein,Envelope glycoprotein,SARS-CoV-2 S protein | | Authors: | Rutten, L, Renault, L.L.R, Juraszek, J, Langedijk, J.P.M. | | Deposit date: | 2020-09-14 | | Release date: | 2020-11-04 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Stabilizing the closed SARS-CoV-2 spike trimer.
Nat Commun, 12, 2021
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7A4N
 | | Cryo-EM structure of a prefusion stabilized SARS-CoV-2 Spike (D614N, R682S, R685G, A892P, A942P and V987P)(S-closed trimer) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin | | Authors: | Rutten, L, Renault, L.L.R, Juraszek, J, Langedijk, J.P.M. | | Deposit date: | 2020-08-20 | | Release date: | 2020-11-04 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Stabilizing the closed SARS-CoV-2 spike trimer.
Nat Commun, 12, 2021
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2ERV
 | | Crystal structure of the outer membrane enzyme PagL | | Descriptor: | CALCIUM ION, PENTAETHYLENE GLYCOL MONODECYL ETHER, hypothetical protein Paer03002360 | | Authors: | Rutten, L, Geurtsen, J, Lambert, W, Smolenaers, J.J, Bonvin, A.M, van der Ley, P, Egmond, M.R, Gros, P, Tommassen, J. | | Deposit date: | 2005-10-25 | | Release date: | 2006-04-11 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 103, 2006
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3FID
 | | LpxR from Salmonella typhimurium | | Descriptor: | GLYCEROL, PENTAETHYLENE GLYCOL MONODECYL ETHER, Putative outer membrane protein (LpxR), ... | | Authors: | Rutten, L, Gros, P. | | Deposit date: | 2008-12-11 | | Release date: | 2009-02-10 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Active-site architecture and catalytic mechanism of the lipid A deacylase LpxR of Salmonella typhimurium
Proc.Natl.Acad.Sci.USA, 106, 2009
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3ESD
 | | cut-2b; NCN-Pt-Pincer-Cutinase Hybrid | | Descriptor: | Cutinase 1, bromo(4-{3-[(R)-ethoxy(4-nitrophenoxy)phosphoryl]propyl}-2,6-bis[(methylsulfanyl-kappaS)methyl]phenyl-kappaC~1~)palladium(2+) | | Authors: | Rutten, L, Mannie, J.P.B.A, Lutz, M, Gros, P. | | Deposit date: | 2008-10-05 | | Release date: | 2009-07-28 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.22 Å) | | Cite: | Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids
Chemistry, 15, 2009
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3EF3
 | | cut-1a; NCN-Pt-Pincer-Cutinase Hybrid | | Descriptor: | (2,6-bis[(dimethylamino-kappaN)methyl]-4-{3-[(S)-ethoxy(4-nitrophenoxy)phosphoryl]propyl}phenyl-kappaC~1~)(chloro)platinum(2+), Cutinase-1 | | Authors: | Rutten, L, Mannie, J.P.B.A, Lutz, M, Gros, P. | | Deposit date: | 2008-09-08 | | Release date: | 2009-07-28 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids
Chemistry, 15, 2009
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3ESC
 | | cut-2a; NCN-Pt-Pincer-Cutinase Hybrid | | Descriptor: | Cutinase 1, bromo(4-{3-[(R)-ethoxy(4-nitrophenoxy)phosphoryl]propyl}-2,6-bis[(methylsulfanyl-kappaS)methyl]phenyl-kappaC~1~)palladium(2+) | | Authors: | Rutten, L, Mannie, J.P.B.A, Lutz, M, Gros, P. | | Deposit date: | 2008-10-05 | | Release date: | 2009-07-28 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids
Chemistry, 15, 2009
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3ESA
 | | cut-1b; NCN-Pt-Pincer-Cutinase Hybrid | | Descriptor: | (2,6-bis[(dimethylamino-kappaN)methyl]-4-{3-[(S)-ethoxy(4-nitrophenoxy)phosphoryl]propyl}phenyl-kappaC~1~)(chloro)platinum(2+), Cutinase 1 | | Authors: | Rutten, L, Mannie, J.P.B.A, Lutz, M, Gros, P. | | Deposit date: | 2008-10-05 | | Release date: | 2009-07-28 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids
Chemistry, 15, 2009
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3ESB
 | | cut-1c; NCN-Pt-Pincer-Cutinase Hybrid | | Descriptor: | (2,6-bis[(dimethylamino-kappaN)methyl]-4-{3-[(S)-ethoxy(4-nitrophenoxy)phosphoryl]propyl}phenyl-kappaC~1~)(chloro)platinum(2+), CHLORIDE ION, Cutinase 1 | | Authors: | Rutten, L, Mannie, J.P.B.A, Lutz, M, Gros, P. | | Deposit date: | 2008-10-05 | | Release date: | 2009-07-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids
Chemistry, 15, 2009
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1I78
 | | CRYSTAL STRUCTURE OF OUTER MEMBRANE PROTEASE OMPT FROM ESCHERICHIA COLI | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, PROTEASE VII, octyl beta-D-glucopyranoside | | Authors: | Vandeputte-Rutten, L, Kramer, R.A, Kroon, J, Dekker, N, Egmond, M.R, Gros, P. | | Deposit date: | 2001-03-08 | | Release date: | 2001-10-03 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site.
EMBO J., 20, 2001
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2BH9
 | | X-RAY STRUCTURE OF A DELETION VARIANT OF HUMAN GLUCOSE 6-PHOSPHATE DEHYDROGENASE COMPLEXED WITH STRUCTURAL AND COENZYME NADP | | Descriptor: | GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Gover, S, Vandeputte-Rutten, L, Au, S.W.N, Adams, M.J. | | Deposit date: | 2005-01-08 | | Release date: | 2005-04-25 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Studies of Glucose-6-Phosphate and Nadp+ Binding to Human Glucose-6-Phosphate Dehydrogenase
Acta Crystallogr.,Sect.D, 61, 2005
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1MNU
 | | UNLIGANDED BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS | | Descriptor: | CADMIUM ION, PROTEIN (IGG2A-KAPPA ANTIBODY MN12H2 (HEAVY CHAIN)), PROTEIN (IGG2A-KAPPA ANTIBODY MN12H2 (LIGHT CHAIN)) | | Authors: | Van Den Elsen, J, Vandeputte-Rutten, L, Kroon, J, Gros, P. | | Deposit date: | 1999-04-30 | | Release date: | 1999-05-06 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Bactericidal antibody recognition of meningococcal PorA by induced fit. Comparison of liganded and unliganded Fab structures.
J.Biol.Chem., 274, 1999
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1P4T
 | | Crystal structure of Neisserial surface protein A (NspA) | | Descriptor: | ETHANOLAMINE, PENTAETHYLENE GLYCOL MONODECYL ETHER, SULFATE ION, ... | | Authors: | Vandeputte-Rutten, L, Bos, M.P, Tommassen, J, Gros, P. | | Deposit date: | 2003-04-24 | | Release date: | 2003-07-22 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structure of Neisserial Surface Protein A (NspA),
a conserved outer membrane protein with vaccine potential
J.Biol.Chem., 278, 2003
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6VKM
 | | Crystal Structure of Stabilized GP from Makona Variant of Ebola Virus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Virion spike glycoprotein | | Authors: | Gilman, M.S.A, Rutten, L, Langedijk, J.P.M, McLellan, J.S. | | Deposit date: | 2020-01-21 | | Release date: | 2020-04-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers.
Cell Rep, 30, 2020
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1E77
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8FU7
 | | Structure of Covid Spike variant deltaN135 in fully closed form | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Yu, X, Juraszek, J, Rutten, L, Bakkers, M.J.G, Blokland, S, Van den Broek, N.J.F, Verwilligen, A.Y.W, Abeywickrema, P, Vingerhoets, J, Neefs, J, Bakhash, S.A.M, Roychoudhury, P, Greninger, A, Sharma, S, Langedijk, J.P.M. | | Deposit date: | 2023-01-16 | | Release date: | 2023-04-05 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike.
Plos Pathog., 19, 2023
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8FU8
 | | Structure of Covid Spike variant deltaN135 with one erect RBD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Yu, X, Juraszek, J, Rutten, L, Bakkers, M.J.G, Blokland, S, Van den Broek, N.J.F, Verwilligen, A.Y.W, Abeywickrema, P, Vingerhoets, J, Neefs, J, Bakhash, S.A.M, Roychoudhury, P, Greninger, A, Sharma, S, Langedijk, J.P.M. | | Deposit date: | 2023-01-16 | | Release date: | 2023-04-05 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike.
Plos Pathog., 19, 2023
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8FU9
 | | Structure of Covid Spike variant deltaN25 with one erect RBD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Yu, X, Juraszek, J, Rutten, L, Bakkers, M.J.G, Blokland, S, Van den Broek, N.J.F, Verwilligen, A.Y.W, Abeywickrema, P, Vingerhoets, J, Neefs, J, Bakhash, S.A.M, Roychoudhury, P, Greninger, A, Sharma, S, Langedijk, J.P.M. | | Deposit date: | 2023-01-16 | | Release date: | 2023-04-05 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike.
Plos Pathog., 19, 2023
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4B41
 | | Crystal structure of an amyloid-beta binding single chain antibody G7 | | Descriptor: | ANTIBODY G7, CHLORIDE ION, GLYCEROL | | Authors: | Beringer, D.X, Dorresteijn, B, Rutten, L, Wienk, H, el Khattabi, M, Kroon-Batenburg, L.M.J, Verrips, C.T. | | Deposit date: | 2012-07-27 | | Release date: | 2013-08-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.191 Å) | | Cite: | Crystal Structure of an Amyloid-Beta Binding Single Chain Antibody G7
To be Published
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4B5E
 | | Crystal Structure of an amyloid-beta binding single chain antibody PS2-8 | | Descriptor: | GLYCEROL, PS2-8, SULFATE ION | | Authors: | Beringer, D.X, Dorresteijn, B, Rutten, L, Wienk, H, el Khattabi, M, Kroon-Batenburg, L.M.J, Verrips, C.T. | | Deposit date: | 2012-08-03 | | Release date: | 2013-08-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.936 Å) | | Cite: | Amyloid-Beta Binding Single Chain Antibody Ps2-8
To be Published
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