9FTI
| Open conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10mM EDTA | Descriptor: | Neurotransmitter-gated ion-channel ligand-binding domain-containing protein | Authors: | Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. | Deposit date: | 2024-06-24 | Release date: | 2024-09-11 | Last modified: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural characterization of pH-modulated closed and open states
in a pentameric ligand-gated ion channel To Be Published
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9FTH
| Open conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10mM Ca2+ | Descriptor: | Neurotransmitter-gated ion-channel ligand-binding domain-containing protein | Authors: | Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. | Deposit date: | 2024-06-24 | Release date: | 2024-09-11 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural characterization of pH-modulated closed and open states
in a pentameric ligand-gated ion channel To Be Published
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9FTJ
| Closed and disordered conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10mM EDTA | Descriptor: | Neurotransmitter-gated ion-channel ligand-binding domain-containing protein | Authors: | Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. | Deposit date: | 2024-06-24 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural characterization of pH-modulated closed and open states
in a pentameric ligand-gated ion channel To Be Published
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9FTG
| Closed conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10 mM Ca2+ | Descriptor: | CALCIUM ION, Neurotransmitter-gated ion-channel ligand-binding domain-containing protein | Authors: | Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. | Deposit date: | 2024-06-24 | Release date: | 2024-09-11 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural characterization of pH-modulated closed and open states
in a pentameric ligand-gated ion channel To Be Published
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6ZGK
| GLIC pentameric ligand-gated ion channel, pH 3 | Descriptor: | Proton-gated ion channel | Authors: | Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E. | Deposit date: | 2020-06-18 | Release date: | 2021-05-26 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations. Life Sci Alliance, 4, 2021
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6ZGD
| GLIC pentameric ligand-gated ion channel, pH 7 | Descriptor: | Proton-gated ion channel | Authors: | Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E. | Deposit date: | 2020-06-18 | Release date: | 2021-05-26 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations. Life Sci Alliance, 4, 2021
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6ZGJ
| GLIC pentameric ligand-gated ion channel, pH 5 | Descriptor: | Proton-gated ion channel | Authors: | Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E. | Deposit date: | 2020-06-18 | Release date: | 2021-05-26 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations. Life Sci Alliance, 4, 2021
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8ATG
| Pentameric ligand-gated ion channel GLIC with bound lipids | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Proton-gated ion channel | Authors: | Bergh, C, Rovsnik, U, Howard, R.J, Lindahl, E. | Deposit date: | 2022-08-23 | Release date: | 2023-09-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM. Elife, 12, 2024
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7Q3H
| Pentameric ligand-gated ion channel, DeCLIC at pH 7 with 10 mM EDTA | Descriptor: | Neur_chan_LBD domain-containing protein | Authors: | Lycksell, M, Rovsnik, U, Hanke, A, Howard, R.J, Lindahl, E. | Deposit date: | 2021-10-27 | Release date: | 2022-11-16 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Q3G
| Pentameric ligand-gated ion channel, DeCLIC at pH 7 with 10 mM Ca2+ | Descriptor: | CALCIUM ION, Neur_chan_LBD domain-containing protein | Authors: | Licksell, M, Rovsnik, U, Hanke, A, Howard, R.J, Lindahl, E. | Deposit date: | 2021-10-27 | Release date: | 2022-11-16 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel. Proc.Natl.Acad.Sci.USA, 119, 2022
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8B7V
| Automated simulation-based refinement of maltoporin into a cryo-EM density | Descriptor: | Maltoporin | Authors: | Yvonnesdotter, L, Rovsnik, U, Blau, C, Lycksell, M, Howard, R.J, Lindahl, E. | Deposit date: | 2022-10-03 | Release date: | 2023-06-21 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Automated simulation-based membrane protein refinement into cryo-EM data. Biophys.J., 122, 2023
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