2HJF
 
 | | Potassium channel kcsa-fab complex with tetrabutylammonium (TBA) | | Descriptor: | Antibody fragment Heavy chain, Antibody fragment Light chain, POTASSIUM ION, ... | | Authors: | Faraldo-Gomez, J.D, Kutluay, E, Jogini, V, Zhao, Y, Heginbotham, L, Roux, B. | | Deposit date: | 2006-06-30 | | Release date: | 2006-12-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Mechanism of Intracellular Block of the KcsA K(+) Channel by Tetrabutylammonium: Insights from X-ray Crystallography, Electrophysiology and Replica-exchange Molecular Dynamics Simulations.
J.Mol.Biol., 365, 2007
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2ATK
 | | Structure of a mutant KcsA K+ channel | | Descriptor: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, NONAN-1-OL, ... | | Authors: | Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Chakrapani, S, Roux, B, Perozo, E. | | Deposit date: | 2005-08-25 | | Release date: | 2006-03-07 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular determinants of gating at the potassium-channel selectivity filter.
Nat.Struct.Mol.Biol., 13, 2006
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2P7T
 | | Crystal Structure of KcsA mutant | | Descriptor: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB-A, FAB-B, ... | | Authors: | Cordero-Morales, J.F, Vishwanath, J, Lewis, A, Valeria, V.R, Cortes, D.M, Roux, B, Perozo, E. | | Deposit date: | 2007-03-20 | | Release date: | 2007-10-09 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal Structure of KcsA mutant
To be Published
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1ZWI
 | | Structure of mutant KcsA potassium channel | | Descriptor: | DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ... | | Authors: | Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Cortes, D.M, Roux, B, Perozo, E. | | Deposit date: | 2005-06-03 | | Release date: | 2006-03-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular determinants of gating at the potassium-channel selectivity filter.
Nat.Struct.Mol.Biol., 13, 2006
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7MDJ
 | | The structure of KcsA in complex with a synthetic Fab | | Descriptor: | Fab heavy chain, Fab light chain, POTASSIUM ION, ... | | Authors: | Rohaim, A, Slezak, T, Blackowicz, L, Kossiakoff, A, Roux, B. | | Deposit date: | 2021-04-05 | | Release date: | 2022-02-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.
J.Gen.Physiol., 154, 2022
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1MAG
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3FB7
 | | Open KcsA potassium channel in the presence of Rb+ ion | | Descriptor: | RUBIDIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | | Authors: | Cuello, L.G, Jogini, V, Cortes, D.M, Pan, A.C, Gagnon, D.H, Cordero-Morales, J.F, Chakrapani, S, Roux, B, Perozo, E. | | Deposit date: | 2008-11-18 | | Release date: | 2010-07-14 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Open KcsA potassium channel in the presence of Rb+ ion
TO BE PUBLISHED
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7MK6
 | | KcsA open gate E71V mutant with sodium | | Descriptor: | Fab heavy chain, Fab light chain, pH-gated potassium channel KcsA | | Authors: | Rohaim, A, Li, J, Weingarth, M, Roux, B. | | Deposit date: | 2021-04-21 | | Release date: | 2022-03-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V.
Nat Commun, 13, 2022
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7MHR
 | | KcsA E71V closed gate with K+ | | Descriptor: | Fab heavy chain, Fab light chain, POTASSIUM ION, ... | | Authors: | Rohaim, A, Li, J, Weingarth, M, Roux, B. | | Deposit date: | 2021-04-15 | | Release date: | 2022-03-23 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V.
Nat Commun, 13, 2022
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7MHX
 | | KcsA E71V closed gate with Ba2+ | | Descriptor: | BARIUM ION, DIACYL GLYCEROL, Fab heavy chain, ... | | Authors: | Rohaim, A, Li, J, Weingarth, M, Roux, B. | | Deposit date: | 2021-04-15 | | Release date: | 2022-03-23 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V.
Nat Commun, 13, 2022
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7MJT
 | | KcsA open gate E71V mutant with Barium | | Descriptor: | BARIUM ION, Fab heavy chain, Fab light chain, ... | | Authors: | Rohaim, A, Li, J, Weingarth, M, Roux, B. | | Deposit date: | 2021-04-20 | | Release date: | 2022-03-23 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V.
Nat Commun, 13, 2022
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7MUB
 | | KcsA Open gate E71V mutant in Potassium | | Descriptor: | Fab heavy chain, Fab light chain, POTASSIUM ION, ... | | Authors: | Rohaim, A, Li, J, Weingarth, M, Roux, B. | | Deposit date: | 2021-05-14 | | Release date: | 2022-03-23 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V.
Nat Commun, 13, 2022
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3OR7
 | | On the structural basis of modal gating behavior in K+channels - E71I | | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | | Authors: | Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Pan, A.C, Cortes, D.M, Roux, B, Perozo, E. | | Deposit date: | 2010-09-06 | | Release date: | 2011-01-05 | | Last modified: | 2018-08-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | On the structural basis of modal gating behavior in K(+) channels.
Nat.Struct.Mol.Biol., 18, 2011
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5I5C
 | | X-ray crystal structure of allo-Thr31-ShK | | Descriptor: | GLYCEROL, Kappa-stichotoxin-She3a, LITHIUM ION, ... | | Authors: | Dang, B, Kubota, T, Manda, K.l, Shen, R, Bezanilla, F, Roux, B, Kent, S.B.H. | | Deposit date: | 2016-02-15 | | Release date: | 2017-01-25 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5I5B
 | | quasi racemic structure of allo-Thr13-ShK and D-ShK | | Descriptor: | D-ShK, GLYCEROL, Kappa-stichotoxin-She3a, ... | | Authors: | Dang, B, Kubota, T, Mandal, K, Shen, R, Bezanilla, F, Roux, B, Kent, S.B.H. | | Deposit date: | 2016-02-15 | | Release date: | 2017-01-25 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (0.9 Å) | | Cite: | Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5I5A
 | | quasi racemic structure of allo-Ile7-ShK and D-ShK | | Descriptor: | D-MALATE, D-ShK, GLYCEROL, ... | | Authors: | Dang, B, Kubota, T, Mandal, K, Shen, R, Bezanilla, F, Roux, B, Kent, S.B.H. | | Deposit date: | 2016-02-14 | | Release date: | 2017-01-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5CBH
 | | Structural and Functional Characterization of a Calcium-activated Cation channel from Tsukamurella Paurometabola | | Descriptor: | CALCIUM ION, Ion transport 2 domain protein | | Authors: | Dhakshnamoorthy, B, Rohaim, A, Rui, H, Blachowicz, L, Roux, B. | | Deposit date: | 2015-06-30 | | Release date: | 2016-07-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.37 Å) | | Cite: | Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola.
Nat Commun, 7, 2016
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4L17
 | | GluA2-L483Y-A665C ligand-binding domain in complex with the antagonist DNQX | | Descriptor: | 6,7-DINITROQUINOXALINE-2,3-DIONE, Glutamate receptor 2, SULFATE ION | | Authors: | Lau, A.Y, Blachowicz, L, Roux, B. | | Deposit date: | 2013-06-02 | | Release date: | 2013-08-14 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A conformational intermediate in glutamate receptor activation.
Neuron, 79, 2013
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5CBF
 | | Structural and Functional Characterization of a Calcium-activated Cation channel from Tsukamurella Paurometabola | | Descriptor: | CALCIUM ION, Ion transport 2 domain protein | | Authors: | Dhakshnamoorthy, B, Rohaim, A, Rui, H, Blachowicz, L, Roux, B. | | Deposit date: | 2015-06-30 | | Release date: | 2016-07-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.61 Å) | | Cite: | Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola.
Nat Commun, 7, 2016
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5CBG
 | | Calcium activated non-selective cation channel | | Descriptor: | CALCIUM ION, DECYL-BETA-D-MALTOPYRANOSIDE, Ion transport 2 domain protein | | Authors: | Dhakshnamoorthy, B, Rohaim, A, Rui, H, Blachowicz, L, Roux, B. | | Deposit date: | 2015-06-30 | | Release date: | 2016-07-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.14 Å) | | Cite: | Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola.
Nat Commun, 7, 2016
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4LSE
 | | Ion selectivity of OmpF porin soaked in 0.2M NaBr | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, BROMIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Balasundaresan, D, Blachowicz, L, Roux, B. | | Deposit date: | 2013-07-22 | | Release date: | 2013-10-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A structural study of ion permeation in OmpF porin from anomalous X-ray diffraction and molecular dynamics simulations.
J.Am.Chem.Soc., 135, 2013
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4LSH
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4LSF
 | | Ion selectivity of OmpF soaked in 0.1M KBr | | Descriptor: | BROMIDE ION, GLYCEROL, Outer membrane protein F | | Authors: | Balasundaresan, D, Blachowicz, L, Roux, B. | | Deposit date: | 2013-07-22 | | Release date: | 2013-10-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A structural study of ion permeation in OmpF porin from anomalous X-ray diffraction and molecular dynamics simulations.
J.Am.Chem.Soc., 135, 2013
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4LSI
 | | Ion selectivity of OmpF porin soaked in 0.3M KBr | | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, BROMIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Balasundaresan, D, Blachowicz, L, Roux, B. | | Deposit date: | 2013-07-22 | | Release date: | 2013-10-23 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.089 Å) | | Cite: | A structural study of ion permeation in OmpF porin from anomalous X-ray diffraction and molecular dynamics simulations.
J.Am.Chem.Soc., 135, 2013
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4GCQ
 | | Crystal Structure of E. coli OmpF porin in complex with Carbenicillin | | Descriptor: | (2S,5R,6R,7R)-6-{[(2R)-2-carboxy-2-phenylacetyl]amino}-7-hydroxy-3,3-dimethyl-4-thia-1-azabicyclo[3.2.0]heptane-2-carbo xylic acid, Outer membrane protein F | | Authors: | Ziervogel, B.K, Roux, B. | | Deposit date: | 2012-07-30 | | Release date: | 2012-12-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Binding of Antibiotics in OmpF Porin.
Structure, 21, 2013
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