8VJD
 
 | | Human R14A Pin1 covalently bound to inhibitor 158F10 in P21 21 21 space group | | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Inhibitor 158F10, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | Authors: | Rodriguez, I, Blaha, G. | | Deposit date: | 2024-01-06 | | Release date: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Targeted Degradation of Pin1 by Protein Destabilizing Compounds
To Be Published
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8VJF
 | | Human R14A Pin1 covalently bound to inhibitor 158D9 | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | | Authors: | Rodriguez, I, Blaha, G. | | Deposit date: | 2024-01-06 | | Release date: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Targeted Degradation of Pin1 by Protein Destabilizing Compounds
To Be Published
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8VJE
 | | Human R14A Pin1 covalently bound to inhibitor 158F10 | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Inhibitor 158F10, ... | | Authors: | Rodriguez, I, Blaha, G. | | Deposit date: | 2024-01-06 | | Release date: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Targeted Degradation of Pin1 by Protein Destabilizing Compounds
To Be Published
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8VJG
 | | Human R14A Pin1 covalently bound to inhibitor 164A10 | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Nalpha-{(2S)-1-[(3S)-2-acetyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carbonyl]piperidine-2-carbonyl}-5-fluoro-L-tryptophanamide, ... | | Authors: | Rodriguez, I, Blaha, G. | | Deposit date: | 2024-01-06 | | Release date: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Targeted Degradation of Pin1 by Protein Destabilizing Compounds
To Be Published
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8ALX
 | | Structure of human PD-L1 in complex with inhibitor | | Descriptor: | 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, AMINOMETHYLAMIDE, ACETATE ION, ... | | Authors: | Rodriguez, I, Grudnik, P, Holak, T, Magiera-Mularz, K. | | Deposit date: | 2022-08-01 | | Release date: | 2023-08-16 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Structural and biological characterization of pAC65, a macrocyclic peptide that blocks PD-L1 with equivalent potency to the FDA-approved antibodies.
Mol Cancer, 22, 2023
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