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PDB: 94 件

5HK5
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Structure of the Grem2-GDF5 Inhibitory Complex
分子名称: Gremlin-2, Growth/differentiation factor 5
著者Nolan, K, Thompson, T.B, Read, R.J.
登録日2016-01-13
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism.
Cell Rep, 16, 2016
2C5C
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BU of 2c5c by Molmil
Shiga-like toxin 1 B subunit complexed with a bivalent inhibitor
分子名称: DIETHYL PROPANE-1,3-DIYLBISCARBAMATE, SHIGA-LIKE TOXIN 1 B SUBUNIT, SULFATE ION, ...
著者Dodd, R.B, Read, R.J.
登録日2005-10-26
公開日2006-11-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Extensive Cross-Linking of the Shiga-Like Toxin 1 B Subunit by a Bivalent Ligand
To be Published
2C4P
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BU of 2c4p by Molmil
Crystal structure of human ubiquitin-conjugating enzyme UbcH5A
分子名称: UBIQUITIN-CONJUGATING ENZYME E2 D1
著者Dodd, R.B, Read, R.J.
登録日2005-10-21
公開日2006-11-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of Two Human Ubiquitin-Conjugating Enzymes from Twinned Crystals
To be Published
2CEO
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BU of 2ceo by Molmil
thyroxine-binding globulin complex with thyroxine
分子名称: 3,5,3',5'-TETRAIODO-L-THYRONINE, GLYCEROL, THYROXINE-BINDING GLOBULIN
著者Zhou, A, Wei, Z, Read, R.J, Carrell, R.W.
登録日2006-02-08
公開日2006-08-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Mechanism for the Carriage and Release of Thyroxine in the Blood.
Proc.Natl.Acad.Sci.USA, 103, 2006
2CLW
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BU of 2clw by Molmil
Crystal structure of human ubiquitin-conjugating enzyme UbcH5B
分子名称: GLYCEROL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E2 D2
著者Dodd, R.B, Read, R.J.
登録日2006-05-02
公開日2007-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.945 Å)
主引用文献Structures of Two Human Ubiquitin-Conjugating Enzymes from Twinned Crystals
To be Published
8AXG
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BU of 8axg by Molmil
Crystal structure of Fusobacterium nucleatum fusolisin protease
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fusolisin, ...
著者Isupov, M.N, Wiener, R, Rouvinski, A, Fahoum, J, Kumar, M, Read, R.J.
登録日2022-08-31
公開日2023-09-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal structure of Fusobacterium nucleatum fusolisin protease
To Be Published
8CKP
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BU of 8ckp by Molmil
X-ray structure of the crystallization-prone form of subfamily III haloalkane dehalogenase DhmeA from Haloferax mediterranei
分子名称: Alpha/beta fold hydrolase, CHLORIDE ION
著者Marek, M, Chmelova, K, Schenkmayerova, A, Croll, T, Read, R.J, Diederichs, K.
登録日2023-02-16
公開日2023-08-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography.
Protein Sci., 32, 2023
1PRT
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BU of 1prt by Molmil
THE CRYSTAL STRUCTURE OF PERTUSSIS TOXIN
分子名称: PERTUSSIS TOXIN (SUBUNIT S1), PERTUSSIS TOXIN (SUBUNIT S2), PERTUSSIS TOXIN (SUBUNIT S3), ...
著者Stein, P.E, Read, R.J.
登録日1993-11-22
公開日1995-01-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The crystal structure of pertussis toxin.
Structure, 2, 1994
4CCC
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BU of 4ccc by Molmil
STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH 4NBDG: ENZYME-SUBSTRATE COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-nitrophenyl beta-D-galactopyranoside, ...
著者Hill, C.H, Graham, S.C, Read, R.J, Deane, J.E.
登録日2013-10-21
公開日2013-12-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
4CCE
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BU of 4cce by Molmil
STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH GALACTOSE: ENZYME- PRODUCT COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Hill, C.H, Graham, S.C, Read, R.J, Deane, J.E.
登録日2013-10-21
公開日2013-12-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
4C41
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Corticosteroid-binding globulin with engineered disulphide bridge between residues 100 and 236
分子名称: CORTICOSTEROID-BINDING GLOBULIN
著者Chan, W.L, Zhou, A, Read, R.J.
登録日2013-08-28
公開日2014-10-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Towards Engineering Hormone-Binding Globulins as Drug Delivery Agents.
Plos One, 9, 2014
4A5M
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BU of 4a5m by Molmil
Redox regulator HypR in its oxidized form
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR YYBR
著者Palm, G.J, Waack, P, Read, R.J, Hinrichs, W.
登録日2011-10-26
公開日2012-01-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Insights Into the Redox-Switch Mechanism of the Marr/Duf24-Type Regulator Hypr
Nucleic Acids Res., 40, 2012
4A5N
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BU of 4a5n by Molmil
Redoxregulator HypR in its reduced form
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR YYBR
著者Palm, G.J, Waack, P, Read, R.J, Hinrichs, W.
登録日2011-10-26
公開日2012-01-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Insights Into the Redox-Switch Mechanism of the Marr/Duf24-Type Regulator Hypr
Nucleic Acids Res., 40, 2012
4C49
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BU of 4c49 by Molmil
Reactive loop cleaved human CBG in complex with cortisol
分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN
著者Chan, W.L, Zhou, A, Read, R.J.
登録日2013-09-02
公開日2014-10-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Role of Sa-Hd Loop Movement in Cortisol Release Mechanism of Cbg
To be Published
4CCD
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BU of 4ccd by Molmil
STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH D-GALACTAL: ENZYME- INTERMEDIATE COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-alpha-D-galactopyranose, ...
著者Hill, C.H, Graham, S.C, Read, R.J, Deane, J.E.
登録日2013-10-21
公開日2013-12-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
4AUT
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BU of 4aut by Molmil
Crystal structure of the tuberculosis drug target Decaprenyl- Phosphoryl-beta-D-Ribofuranose-2-oxidoreductase (DprE1) from Mycobacterium smegmatis
分子名称: DECAPRENYL-PHOSPHORYL-BETA-D-RIBOFURANOSE-2-OXIDOREDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE
著者Neres, J, Pojer, F, Molteni, E, Chiarelli, L.R, Dhar, N, Boy-Rottger, S, Buroni, S, Fullam, E, Degiacomi, G, Lucarelli, A, Read, R.J, Zanoni, G, Edmondson, D.E, De Rossi, E, Pasca, M, Riccardi, G, Mattevi, A, Dyson, P.J, Cole, S.T, Binda, C.
登録日2012-05-21
公開日2012-09-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium Tuberculosis.
Sci. Transl. Med., 4, 2012
1BCP
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BU of 1bcp by Molmil
BINARY COMPLEX OF PERTUSSIS TOXIN AND ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, PERTUSSIS TOXIN
著者Hazes, B, Read, R.J.
登録日1995-11-21
公開日1997-06-05
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the pertussis toxin-ATP complex: a molecular sensor.
J.Mol.Biol., 258, 1996
1BOS
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BU of 1bos by Molmil
SHIGA-LIKE TOXIN COMPLEXED WITH ITS RECEPTOR
分子名称: SHIGA-LIKE TOXIN I B SUBUNIT, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ...
著者Ling, H, Boodhoo, A, Hazes, B, Cummings, M.D, Armstrong, G.D, Brunton, J.L, Read, R.J.
登録日1998-01-13
公開日1999-02-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the shiga-like toxin I B-pentamer complexed with an analogue of its receptor Gb3.
Biochemistry, 37, 1998
1C48
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MUTATED SHIGA-LIKE TOXIN B SUBUNIT (G62T)
分子名称: PROTEIN (SHIGA-LIKE TOXIN I B SUBUNIT)
著者Ling, H, Bast, D, Brunton, J.L, Read, R.J.
登録日1999-08-11
公開日2000-08-16
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification of the Primary Receptor Binding Site of Shiga-Like Toxin B Subunits: Structures of Mutated Shiga-Like Toxin I B-Pentamer with and without Bound Carbohydrate
To be Published
1C4Q
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BU of 1c4q by Molmil
MUTATED SHIGA-LIKE TOXIN B SUBUNIT (F30A/W34A) COMPLEXED WITH RECEPTOR GB3 ANALOGUE
分子名称: PROTEIN (SHIGA-LIKE TOXIN I SUBUNIT B), alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Ling, H, Brunton, J.L, Read, R.J.
登録日1999-08-31
公開日2000-09-20
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Identification of the Primary Receptor Binding Site of Shiga-Like Toxin B Subunits: Structures of Mutated Shiga-Like Toxin I B-Pentamer with and without Bound Carbohydrate
To be Published
1DZO
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BU of 1dzo by Molmil
Truncated PAK pilin from Pseudomonas aeruginosa
分子名称: TYPE IV PILIN
著者Hazes, B, Read, R.J.
登録日2000-03-06
公開日2000-06-11
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystal Structure of Pseudomonas Aeruginosa Pak Pilin Suggests a Main-Chain-Dominated Mode of Receptor Binding
J.Mol.Biol., 299, 2000
1D1K
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BU of 1d1k by Molmil
MUTATED SHIGA-LIKE TOXIN B SUBUNIT (D17E/W34A) COMPLEXED WITH RECEPTOR GB3 ANALOGUE
分子名称: SHIGA-LIKE TOXIN I SUBUNIT B, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
著者Ling, H, Brunton, J.L, Read, R.J.
登録日1999-09-17
公開日2000-09-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mutated Shiga-like toxin B subunit (D17E/W34A) complexed with receptor Gb3 analogue
To be Published
1CHO
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BU of 1cho by Molmil
CRYSTAL AND MOLECULAR STRUCTURES OF THE COMPLEX OF ALPHA-*CHYMOTRYPSIN WITH ITS INHIBITOR TURKEY OVOMUCOID THIRD DOMAIN AT 1.8 ANGSTROMS RESOLUTION
分子名称: ALPHA-CHYMOTRYPSIN A, TURKEY OVOMUCOID THIRD DOMAIN (OMTKY3)
著者Fujinaga, M, Sielecki, A.R, Read, R.J, Ardelt, W, Laskowskijunior, M, James, M.N.G.
登録日1988-03-04
公開日1988-07-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal and molecular structures of the complex of alpha-chymotrypsin with its inhibitor turkey ovomucoid third domain at 1.8 A resolution.
J.Mol.Biol., 195, 1987
1CQF
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BU of 1cqf by Molmil
THE COMPLEX OF THE MUTATED SHIGA TOXIN B SUBUNIT AND GB3 TRISACCHARIDE
分子名称: SHIGA TOXIN B-CHAIN, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Ling, H, Bast, D, Brunton, J.L, Read, R.J.
登録日1999-08-06
公開日2000-08-07
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Complex of the Mutated Shiga Toxin B Subunit and Gb3 Trisaccharide
To be Published
1D1I
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BU of 1d1i by Molmil
MUTATED SHIGA-LIKE TOXIN B SUBUNIT (W34A) COMPLEXED WITH RECEPTOR GB3 ANALOGUE
分子名称: SHIGA TOXIN B-CHAIN, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Ling, H, Boodhoo, A, Brunton, J.L, Read, R.J.
登録日1999-09-17
公開日2000-09-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mutated Shiga-like Toxin B Subunit (W34A) Complexed with Receptor Gb3 Analogue
To be Published

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