3COH
 
 | | Crystal structure of Aurora-A in complex with a pentacyclic inhibitor | | 分子名称: | 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1H)-one, Serine/threonine-protein kinase 6 | | 著者 | Wiesmann, C, Raswson, T.E, Cochran, A.G. | | 登録日 | 2008-03-28 | | 公開日 | 2009-02-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability.
J.Med.Chem., 51, 2008
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