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PDB: 41 件

3JCG
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Cryo-EM structure of the magnesium channel CorA in the magnesium-free, asymmetric open state I
分子名称: Magnesium transport protein CorA
著者Matthies, D, Perozo, E, Subramaniam, S.
登録日2015-12-11
公開日2016-02-17
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7.06 Å)
主引用文献Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Cell(Cambridge,Mass.), 164, 2016
8DDJ
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Open MscS in PC14.1 Nanodiscs
分子名称: Mechanosensitive channel MscS
著者Reddy, B.G, Bavi, N, Perozo, E.
登録日2022-06-18
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels.
Elife, 12, 2023
8UC1
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Cryo-EM structure of dolphin Prestin in low Cl buffer
分子名称: CHLORIDE ION, Prestin
著者Haller, P, Bavi, N, Perozo, E.
登録日2023-09-25
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Folding of prestin's anion-binding site and the mechanism of outer hair cell electromotility.
Elife, 12, 2023
1JQ2
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POTASSIUM CHANNEL (KCSA) OPEN GATE MODEL
分子名称: VOLTAGE-GATED POTASSIUM CHANNEL
著者Liu, Y.-S, Sompornpisut, P, Perozo, E.
登録日2001-08-03
公開日2001-10-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the KcsA channel intracellular gate in the open state.
Nat.Struct.Biol., 8, 2001
1JQ1
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POTASSIUM CHANNEL (KCSA) OPEN GATE MODEL
分子名称: VOLTAGE-GATED POTASSIUM CHANNEL
著者Liu, Y.-S, Sompornpisut, P, Perozo, E.
登録日2001-08-03
公開日2001-10-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the KcsA channel intracellular gate in the open state.
Nat.Struct.Biol., 8, 2001
2QI9
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ABC-transporter BtuCD in complex with its periplasmic binding protein BtuF
分子名称: DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, PHOSPHATE ION, ...
著者Hvorup, R.N, Goetz, B.A, Niederer, M, Hollenstein, K, Perozo, E, Locher, K.P.
登録日2007-07-03
公開日2007-08-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF.
Science, 317, 2007
2ATK
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BU of 2atk by Molmil
Structure of a mutant KcsA K+ channel
分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, NONAN-1-OL, ...
著者Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Chakrapani, S, Roux, B, Perozo, E.
登録日2005-08-25
公開日2006-03-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular determinants of gating at the potassium-channel selectivity filter.
Nat.Struct.Mol.Biol., 13, 2006
1ZWI
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BU of 1zwi by Molmil
Structure of mutant KcsA potassium channel
分子名称: DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ...
著者Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Cortes, D.M, Roux, B, Perozo, E.
登録日2005-06-03
公開日2006-03-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular determinants of gating at the potassium-channel selectivity filter.
Nat.Struct.Mol.Biol., 13, 2006
1F6G
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POTASSIUM CHANNEL (KCSA) FULL-LENGTH FOLD
分子名称: VOLTAGE-GATED POTASSIUM CHANNEL
著者Cortes, D.M, Perozo, E.
登録日2000-06-21
公開日2001-02-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating.
J.Gen.Physiol., 117, 2001
2P7T
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Crystal Structure of KcsA mutant
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB-A, FAB-B, ...
著者Cordero-Morales, J.F, Vishwanath, J, Lewis, A, Valeria, V.R, Cortes, D.M, Roux, B, Perozo, E.
登録日2007-03-20
公開日2007-10-09
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of KcsA mutant
To be Published
6V1X
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Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Tetramer
分子名称: (2S)-1-(nonanoyloxy)-3-(phosphonooxy)propan-2-yl tetradecanoate, (3beta,5beta,14beta,17alpha)-cholestan-3-ol, Potassium channel KAT1
著者Clark, M.D, Contreras, G.F, Shen, R, Perozo, E.
登録日2019-11-21
公開日2020-06-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Electromechanical coupling in the hyperpolarization-activated K + channel KAT1.
Nature, 583, 2020
6V1Y
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Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Octamer
分子名称: (2S)-1-(nonanoyloxy)-3-(phosphonooxy)propan-2-yl tetradecanoate, (3beta,5beta,14beta,17alpha)-cholestan-3-ol, Potassium channel KAT1
著者Clark, M.D, Contreras, G.F, Shen, R, Perozo, E.
登録日2019-11-21
公開日2020-06-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Electromechanical coupling in the hyperpolarization-activated K + channel KAT1.
Nature, 583, 2020
6PWN
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MscS Nanodisc with N-terminal His-Tag
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, HEXADECANE, Small-conductance mechanosensitive channel
著者Reddy, B.G, Perozo, E.
登録日2019-07-23
公開日2020-01-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS.
Elife, 8, 2019
3STL
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BU of 3stl by Molmil
KcsA potassium channel mutant Y82C with Cadmium bound
分子名称: CADMIUM ION, POTASSIUM ION, Voltage-gated potassium channel, ...
著者Raghuraman, H, Cordero-Morales, J, Jogini, V, Perozo, E.
登録日2011-07-11
公開日2012-04-18
最終更新日2012-10-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of Cd(2+) Coordination during Slow Inactivation in Potassium Channels.
Structure, 20, 2012
6PWO
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MscS DDM
分子名称: Small-conductance mechanosensitive channel
著者Reddy, B.G, Perozo, E.
登録日2019-07-23
公開日2020-01-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS.
Elife, 8, 2019
3STZ
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BU of 3stz by Molmil
KcsA potassium channel mutant Y82C with nitroxide spin label
分子名称: POTASSIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, Voltage-gated potassium channel, ...
著者Raghuraman, H, Cordero-Morales, J, Jogini, V, Perozo, E.
登録日2011-07-11
公開日2012-04-18
最終更新日2012-10-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanism of Cd(2+) Coordination during Slow Inactivation in Potassium Channels.
Structure, 20, 2012
6PWP
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MscS Nanodisc
分子名称: Small-conductance mechanosensitive channel
著者Reddy, B.G, Perozo, E.
登録日2019-07-23
公開日2020-01-08
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS.
Elife, 8, 2019
5VKH
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BU of 5vkh by Molmil
Closed conformation of KcsA Y82A-F103A mutant
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ...
著者Cuello, L.G, Perozo, E, Cortes, D.M.
登録日2017-04-21
公開日2017-12-06
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The gating cycle of a K+ channel at atomic resolution.
Elife, 6, 2017
5VK6
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BU of 5vk6 by Molmil
Open conformation of KcsA non-inactivating E71A mutant
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ...
著者Cuello, L.G, Perozo, E.
登録日2017-04-21
公開日2017-12-06
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The gating cycle of a K+ channel at atomic resolution.
Elife, 6, 2017
5VKE
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Open conformation of KcsA deep-inactivated
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ...
著者Cuello, L.G, Perozo, E, Cortes, D.M.
登録日2017-04-21
公開日2017-12-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献The gating cycle of a K+ channel at atomic resolution.
Elife, 6, 2017
7S9C
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Cryo-EM Structure of dolphin Prestin: Sensor Down II (Expanded II) state
分子名称: Prestin
著者Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E.
登録日2021-09-20
公開日2021-11-03
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021
3OR6
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On the structural basis of modal gating behavior in K+channels - E71Q
分子名称: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
著者Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Perozo, E.
登録日2010-09-06
公開日2011-01-05
最終更新日2018-08-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献On the structural basis of modal gating behavior in K(+) channels.
Nat.Struct.Mol.Biol., 18, 2011
7S9E
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Cryo-EM Structure of dolphin Prestin: Inhibited II (Sulfate +Salicylate) state
分子名称: 2-HYDROXYBENZOIC ACID, Prestin
著者Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E.
登録日2021-09-20
公開日2021-11-03
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021
7S8X
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Cryo-EM Structure of dolphin Prestin: Sensor Up (compact) state
分子名称: Prestin
著者Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E.
登録日2021-09-20
公開日2021-11-03
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021
7S9D
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Cryo-EM Structure of dolphin Prestin: Intermediate state
分子名称: Prestin
著者Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E.
登録日2021-09-20
公開日2021-11-03
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021

 

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