1VR1
| Specifity for Plasminogen Activator Inhibitor-1 | Descriptor: | Hirudin, thrombin | Authors: | Dekker, R.J, Eichinger, A, Stoop, A.A, Bode, W, Pannekoek, H, Horrevoets, A.J.G. | Deposit date: | 1998-12-11 | Release date: | 1999-12-29 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop J.Mol.Biol., 293, 1999
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