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7MCK
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Structure of CHK1 10-pt. mutant complex with LRRK2 inhibitor 18
Descriptor: N-{5-[(3S)-3-(2-hydroxypropan-2-yl)pyrrolidin-1-yl]-2-(trifluoromethyl)pyridin-3-yl}-6-(1-methyl-1H-pyrazol-4-yl)pyridine-2-carboxamide, Serine/threonine-protein kinase Chk1
Authors:Palte, R.
Deposit date:2021-04-02
Release date:2021-06-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors.
Rsc Med Chem, 12, 2021

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건을2024-11-06부터공개중

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