6F2W
 
 | | Bacterial asc transporter crystal structure in open to in conformation | | 分子名称: | ALPHA-AMINOISOBUTYRIC ACID, Nanobody 74, Putative amino acid/polyamine transport protein, ... | | 著者 | Fort, J, Errasti-Murugarren, E, Carpena, X, Palacin, M, Fita, I. | | 登録日 | 2017-11-27 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction.
Nat Commun, 10, 2019
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8RHJ
 | | Yeast 20S proteasome in complex with a macrocyclic oxindole epoxyketone (compound 5) | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Macrocyclic oxindole epoxyketone, ... | | 著者 | Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M. | | 登録日 | 2023-12-15 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome.
Acs Med.Chem.Lett., 15, 2024
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8RHL
 | | Yeast 20S proteasome in complex with a linear biarylether epoxyketone (compound 15a) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Linear biarylether epoxyketone, ... | | 著者 | Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M. | | 登録日 | 2023-12-15 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome.
Acs Med.Chem.Lett., 15, 2024
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8RHK
 | | Yeast 20S proteasome in complex with a linear oxindole epoxyketone (compound 6) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Linear oxindole epoxyketone, ... | | 著者 | Goetz, M.G, Godwin, K, Price, R, Dorn, R, Merrill-Steskal, G, Hansen, H, Klemmer, W, Produturi, G, Rocha, M, Palmer, M, Molacek, L, Strater, Z, Groll, M. | | 登録日 | 2023-12-15 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome.
Acs Med.Chem.Lett., 15, 2024
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8PUH
 | | Structure of the immature HTLV-1 CA lattice from full-length Gag VLPs: CA-CTD refinement | | 分子名称: | Gag polyprotein | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PU6
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: pooled class | | 分子名称: | Gag protein (Fragment) | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PU7
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle -20 degrees | | 分子名称: | Gag protein (Fragment) | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PUA
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle -05 degrees | | 分子名称: | Gag protein (Fragment) | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PU9
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle -10 degrees | | 分子名称: | Gag protein (Fragment) | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PUB
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle 0 degrees | | 分子名称: | Gag protein (Fragment) | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PUC
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle 05 degrees | | 分子名称: | Gag protein (Fragment) | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PUD
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle 10 degrees | | 分子名称: | Gag protein (Fragment) | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PU8
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle -15 degrees | | 分子名称: | Gag protein (Fragment) | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PUF
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle 20 degrees | | 分子名称: | Gag protein (Fragment) | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PUE
 | | Structure of immature HTLV-1 CA-NTD from in vitro assembled MA126-CANC tubes: axis angle 15 degrees | | 分子名称: | Gag protein (Fragment) | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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8PUG
 | | Structure of the immature HTLV-1 CA lattice from full-length Gag VLPs: CA-NTD refinement | | 分子名称: | Gag polyprotein | | 著者 | Obr, M, Percipalle, M, Chernikova, D, Yang, H, Thader, A, Pinke, G, Porley, D, Mansky, L.M, Dick, R.A, Schur, F.K.M. | | 登録日 | 2023-07-17 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Unconventional stabilization of the human T-cell leukemia virus type 1 immature Gag lattice.
Biorxiv, 2023
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1NPJ
 | | Crystal structure of H145A mutant of nitrite reductase from Alcaligenes faecalis | | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase | | 著者 | Wijma, H.J, Boulanger, M.J, Molon, A, Fittipaldi, M, Huber, M, Murphy, M.E, Verbeet, M.P, Canters, G.W. | | 登録日 | 2003-01-18 | | 公開日 | 2003-04-29 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Reconstitution of the type-1 active site of the H145G/A variants of nitrite reductase by ligand insertion
Biochemistry, 42, 2003
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8QEY
 | | Structure of human Asc1/CD98hc heteromeric amino acid transporter | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, ... | | 著者 | Martinez-Molledo, M, Rullo-Tubau, J, Errasti-Murugarren, E, Palacin, M, Llorca, O. | | 登録日 | 2023-09-01 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure and mechanisms of transport of human Asc1/CD98hc amino acid transporter.
Nat Commun, 15, 2024
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7TNG
 | | Kringle domain of human Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) | | 分子名称: | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | | 著者 | Guarino, S.R, Di Bello, A, Palamini, M, Forneris, F. | | 登録日 | 2022-01-21 | | 公開日 | 2022-05-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1)
Acta Crystallogr.,Sect.F, 78, 2022
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4WGI
 | | A Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1) | | 分子名称: | (2S)-2-[(2S,3R)-10-{[(4-fluorophenyl)sulfonyl]amino}-3-methyl-2-[(methyl{[4-(trifluoromethyl)phenyl]carbamoyl}amino)methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-5(6H)-yl]propanoic acid, FORMIC ACID, MAGNESIUM ION, ... | | 著者 | Clifton, M.C, Fairman, J.W, Fang, C, D'Souza, B, Fulroth, B, Leed, A, McCarren, P, Wang, L, Wang, Y, Kaushik, V, Palmer, M, Wei, G, Golub, T.R, Hubbard, B.K, Serrano-Wu, M.H. | | 登録日 | 2014-09-18 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1).
Acs Med.Chem.Lett., 5, 2014
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3OB6
 | | Structure of AdiC(N101A) in the open-to-out Arg+ bound conformation | | 分子名称: | ARGININE, AdiC arginine:agmatine antiporter | | 著者 | Carpena, X, Kowalczyk, L, Ratera, M, Valencia, E, Vazquez-lbar, J.L, Fita, I, Palacin, M. | | 登録日 | 2010-08-06 | | 公開日 | 2011-03-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Molecular basis of substrate-induced permeation by an amino acid antiporter.
Proc.Natl.Acad.Sci.USA, 108, 2011
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7AH1
 | | L19 diabody fragment from immunocytokine L19-IL2 | | 分子名称: | Anti-(ED-B) scFV | | 著者 | Ongaro, T, Guarino, S.R, Scietti, L, Palamini, M, Wulhfard, S, Villa, A, Neri, D, Forneris, F. | | 登録日 | 2020-09-23 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Inference of molecular structure for characterization and improvement of clinical grade immunocytokines.
J.Struct.Biol., 213, 2021
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1C4O
 | | CRYSTAL STRUCTURE OF THE DNA NUCLEOTIDE EXCISION REPAIR ENZYME UVRB FROM THERMUS THERMOPHILUS | | 分子名称: | DNA NUCLEOTIDE EXCISION REPAIR ENZYME UVRB, SULFATE ION, octyl beta-D-glucopyranoside | | 著者 | Machius, M, Henry, L, Palnitkar, M, Deisenhofer, J. | | 登録日 | 1999-09-14 | | 公開日 | 2000-07-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of the DNA nucleotide excision repair enzyme UvrB from Thermus thermophilus.
Proc.Natl.Acad.Sci.USA, 96, 1999
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1U3D
 | | Crystal Structure of the PHR domain of Cryptochrome 1 from Arabidopsis thaliana with AMPPNP bound | | 分子名称: | CHLORIDE ION, Cryptochrome 1 apoprotein, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, ... | | 著者 | Brautigam, C.A, Smith, B.S, Ma, Z, Palnitkar, M, Tomchick, D.R, Machius, M, Deisenhofer, J. | | 登録日 | 2004-07-21 | | 公開日 | 2004-08-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1NPN
 | | Crystal structure of a copper reconstituted H145A mutant of nitrite reductase from Alcaligenes faecalis | | 分子名称: | CHLORIDE ION, COPPER (II) ION, Copper-containing nitrite reductase | | 著者 | Wijma, H.J, Boulanger, M.J, Molon, A, Fittipaldi, M, Huber, M, Murphy, M.E, Verbeet, M.P, Canters, G.W. | | 登録日 | 2003-01-18 | | 公開日 | 2003-04-29 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Reconstitution of the type-1 active site of the 145G/A variants of Nitrite Reductase by ligand insertion
Biochemistry, 42, 2003
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