7EJ4
 
 | | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-25 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RBD-chAb-25, ... | | 著者 | Yang, T.J, Yu, P.Y, Wu, H.C, Hsu, S.T.D. | | 登録日 | 2021-04-01 | | 公開日 | 2021-06-23 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-25
To be published
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1XA3
 | | Crystal structure of CaiB, a type III CoA transferase in carnitine metabolism | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Crotonobetainyl-CoA:carnitine CoA-transferase, SULFATE ION | | 著者 | Stenmark, P, Gurmu, D, Nordlund, P, Structural Proteomics in Europe (SPINE) | | 登録日 | 2004-08-25 | | 公開日 | 2004-11-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal Structure of CaiB, a Type-III CoA Transferase in Carnitine Metabolism
Biochemistry, 43, 2004
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7EAZ
 | | Cryo-EM structure of SARS-CoV-2 Spike D614G variant, one RBD-up conformation 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | | 登録日 | 2021-03-08 | | 公開日 | 2021-06-23 | | 最終更新日 | 2022-01-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation.
J.Biol.Chem., 297, 2021
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8GII
 | | TEM-1 Beta Lactamase Variant 80.a | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, TEM-1 Variant 80.a | | 著者 | Fram, B.F, Gauthier, N.P, Khan, A.R, Sander, C. | | 登録日 | 2023-03-14 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Simultaneous enhancement of multiple functional properties using evolution-informed protein design.
Nat Commun, 15, 2024
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8GIJ
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1XRP
 | | Crystal structure of active site F1-mutant E213Q soaked with peptide Pro-Leu-Gly-Gly | | 分子名称: | PLGG, PROLINE, Proline iminopeptidase | | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | | 登録日 | 2004-10-15 | | 公開日 | 2005-07-12 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum
J.Biol.Chem., 280, 2005
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7EJ5
 | | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-45 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RBD-chAb45, ... | | 著者 | Yang, T.J, Yu, P.Y, Wu, H.C, Hsu, S.T.D. | | 登録日 | 2021-04-01 | | 公開日 | 2021-06-23 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-45
To Be Published
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5M30
 | | Structure of TssK from T6SS EAEC in complex with nanobody nb18 | | 分子名称: | Anti-vesicular stomatitis virus N VHH, Type VI secretion protein | | 著者 | Nguyen, V.S, Cambillau, C, Spinelli, C, Desmyter, A, Legrand, P, Cascales, E. | | 登録日 | 2016-10-13 | | 公開日 | 2017-06-21 | | 最終更新日 | 2017-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
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3MBA
 | | APLYSIA LIMACINA MYOGLOBIN. CRYSTALLOGRAPHIC ANALYSIS AT 1.6 ANGSTROMS RESOLUTION | | 分子名称: | FLUORIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Bolognesi, M, Onesti, S, Gatti, G, Coda, A, Ascenzi, P, Brunori, M. | | 登録日 | 1989-02-22 | | 公開日 | 1990-01-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Aplysia limacina myoglobin. Crystallographic analysis at 1.6 A resolution.
J.Mol.Biol., 205, 1989
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5TZO
 | | Computationally Designed Fentanyl Binder - Fen49*-Complex | | 分子名称: | CHLORIDE ION, Endo-1,4-beta-xylanase A, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide, ... | | 著者 | Bick, M.J, Greisen, P.J, Morey, K.J, Antunes, M.S, La, D, Sankaran, B, Reymond, L, Johnsson, K, Medford, J.I, Baker, D. | | 登録日 | 2016-11-22 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Computational design of environmental sensors for the potent opioid fentanyl.
Elife, 6, 2017
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7EB5
 | | Cryo-EM structure of SARS-CoV-2 Spike D614G variant, two RBD-up conformation 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | | 登録日 | 2021-03-08 | | 公開日 | 2021-06-23 | | 最終更新日 | 2022-01-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation.
J.Biol.Chem., 297, 2021
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4AQD
 | | Crystal structure of fully glycosylated human butyrylcholinesterase | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Brazzolotto, X, Wandhammer, M, Ronco, C, Trovaslet, M, Jean, L, Lockridge, O, Renard, P.Y, Nachon, F. | | 登録日 | 2012-04-16 | | 公開日 | 2012-07-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure.
FEBS J., 279, 2012
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7EB3
 | | Cryo-EM structure of SARS-CoV-2 Spike D614G variant, one RBD-up conformation 3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | | 登録日 | 2021-03-08 | | 公開日 | 2021-06-23 | | 最終更新日 | 2022-01-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation.
J.Biol.Chem., 297, 2021
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1X8E
 | | Crystal structure of Pyrococcus furiosus phosphoglucose isomerase free enzyme | | 分子名称: | Glucose-6-phosphate isomerase | | 著者 | Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J. | | 登録日 | 2004-08-18 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
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2ZM6
 | | Crystal structure of the Thermus thermophilus 30S ribosomal subunit | | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Kaminishi, T, Wang, H, Kawazoe, M, Ishii, R, Schluenzen, F, Hanawa-Suetsugu, K, Wilson, D.N, Nomura, M, Takemoto, C, Shirouzu, M, Fucini, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-04-11 | | 公開日 | 2009-04-14 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Crystal structure of the Thermus thermophilus 30S ribosomal subunit
To be Published
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7EB4
 | | Cryo-EM structure of SARS-CoV-2 Spike D614G variant, two RBD-up conformation 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Yang, T.J, Yu, P.Y, Chang, Y.C, Hsu, S.T.D. | | 登録日 | 2021-03-08 | | 公開日 | 2021-06-23 | | 最終更新日 | 2022-01-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation.
J.Biol.Chem., 297, 2021
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1AE7
 | | NOTEXIN, A PRESYNAPTIC NEUROTOXIC PHOSPHOLIPASE A2 | | 分子名称: | PHOSPHOLIPASE A2, SULFATE ION | | 著者 | Westerlund, B, Nordlund, P, Uhlin, U, Eaker, D, Eklund, H. | | 登録日 | 1997-03-06 | | 公開日 | 1997-05-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The three-dimensional structure of notexin, a presynaptic neurotoxic phospholipase A2 at 2.0 A resolution.
FEBS Lett., 301, 1992
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5AG8
 | | CRYSTAL STRUCTURE OF A MUTANT (665I6H) OF THE C-TERMINAL DOMAIN OF RGPB | | 分子名称: | GINGIPAIN R2, GLYCEROL, SULFATE ION | | 著者 | de Diego, I, Ksiazek, M, Mizgalska, D, Golik, P, Szmigielski, B, Nowak, M, Nowakowska, Z, Potempa, B, Koneru, L, Nguyen, K.A, Enghild, J, Thogersen, I.B, Dubin, G, Gomis-Ruth, F.X, Potempa, J. | | 登録日 | 2015-01-29 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Outer-Membrane Export Signal of Porphyromonas Gingivalis Type Ix Secretion System (T9Ss) is a Conserved C-Terminal Beta-Sandwich Domain.
Sci.Rep., 6, 2016
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5U3Y
 | | Human PPARdelta ligand-binding domain in complexed with specific agonist 9 | | 分子名称: | 6-[2-({cyclopropyl[4-(furan-2-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor delta, ... | | 著者 | Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P. | | 登録日 | 2016-12-03 | | 公開日 | 2017-03-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3SZQ
 | | Structure of an S. pombe APTX/DNA/AMP/Zn complex | | 分子名称: | 5'-D(*CP*CP*CP*TP*G)-3', 5'-D(*TP*AP*TP*CP*GP*GP*AP*AP*TP*CP*AP*GP*GP*G)-3', ADENOSINE MONOPHOSPHATE, ... | | 著者 | Tumbale, P, Krahn, J, Williams, R.S. | | 登録日 | 2011-07-19 | | 公開日 | 2011-10-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.353 Å) | | 主引用文献 | Structure of an aprataxin-DNA complex with insights into AOA1 neurodegenerative disease.
Nat.Struct.Mol.Biol., 18, 2011
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1ABA
 | | THE STRUCTURE OF OXIDIZED BACTERIOPHAGE T4 GLUTAREDOXIN (THIOREDOXIN). REFINEMENT OF NATIVE AND MUTANT PROTEINS | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTAREDOXIN | | 著者 | Eklund, H, Ingelman, M, Soderberg, B.-O, Uhlin, T, Nordlund, P, Nikkola, M, Sonnerstam, U, Joelson, T, Petratos, K. | | 登録日 | 1992-04-24 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure of oxidized bacteriophage T4 glutaredoxin (thioredoxin). Refinement of native and mutant proteins.
J.Mol.Biol., 228, 1992
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1PLO
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3MXO
 | | Crystal structure oh human phosphoglycerate mutase family member 5 (PGAM5) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Chaikuad, A, Alfano, I, Picaud, S, Filippakopoulos, P, Barr, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Takeda, K, Ichijo, H, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2010-05-07 | | 公開日 | 2010-09-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly.
Structure, 25, 2017
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6ZJ6
 | | Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with cyclohexylmethyl-Glc-1,3-isofagomine | | 分子名称: | 1,2-ETHANEDIOL, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, ACETATE ION, ... | | 著者 | Thompson, A.J, Sobala, L.F, Fernandes, P.Z, Hakki, Z, Howe, J.D, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, T.D, Alonzi, D.S, Williams, S.J, Davies, G.J. | | 登録日 | 2020-06-27 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Proc.Natl.Acad.Sci.USA, 117, 2020
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1ANT
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