6B5Z
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![BU of 6b5z by Molmil](/molmil-images/mine/6b5z) | IMPase (AF2372) with 25 mM Asp | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, ASPARTIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B62
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![BU of 6b62 by Molmil](/molmil-images/mine/6b62) | IMPase (AF2372) with 400 mM Glutamate | Descriptor: | Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, GLUTAMIC ACID, GLYCEROL, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B61
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![BU of 6b61 by Molmil](/molmil-images/mine/6b61) | IMPase (AF2372) with 25 mM Asp | Descriptor: | ASPARTIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, MAGNESIUM ION, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B63
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![BU of 6b63 by Molmil](/molmil-images/mine/6b63) | IMPase (AF2372) with 25 mM Asp | Descriptor: | (2R)-2,3-dihydroxypropyl (2S)-2,3-dihydroxypropyl hydrogen phosphate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.696 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B64
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![BU of 6b64 by Molmil](/molmil-images/mine/6b64) | IMPase (AF2372) with 25 mM Asp | Descriptor: | ASPARTIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, MAGNESIUM ION, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B66
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![BU of 6b66 by Molmil](/molmil-images/mine/6b66) | IMPase (AF2372) R92Q/K164E with 400 mM Glutamate | Descriptor: | Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, GLUTAMIC ACID, GLYCEROL, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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1G0H
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![BU of 1g0h by Molmil](/molmil-images/mine/1g0h) | CRYSTAL STRUCTURE OF MJ0109 GENE PRODUCT INOSITOL MONOPHOSPHATASE-FRUCTOSE 1,6 BISPHOSPHATASE | Descriptor: | CALCIUM ION, D-MYO-INOSITOL-1-PHOSPHATE, INOSITOL MONOPHOSPHATASE | Authors: | Johnson, K.A, Chen, L, Yang, H, Roberts, M.F, Stec, B. | Deposit date: | 2000-10-06 | Release date: | 2001-03-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure and catalytic mechanism of the MJ0109 gene product: a bifunctional enzyme with inositol monophosphatase and fructose 1,6-bisphosphatase activities. Biochemistry, 40, 2001
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4S3G
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![BU of 4s3g by Molmil](/molmil-images/mine/4s3g) | Structure of the F249X mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, ACETATE ION | Authors: | He, T, Gershenson, A, Eyles, S.J, Gao, J, Roberts, M.F. | Deposit date: | 2015-01-26 | Release date: | 2015-07-01 | Last modified: | 2015-08-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Fluorinated Aromatic Amino Acids Distinguish Cation-pi Interactions from Membrane Insertion. J.Biol.Chem., 290, 2015
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2QFL
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![BU of 2qfl by Molmil](/molmil-images/mine/2qfl) | Structure of SuhB: Inositol monophosphatase and extragenic suppressor from E. coli | Descriptor: | ACETATE ION, ETHYL ACETATE, Inositol-1-monophosphatase | Authors: | Wang, Y, Stieglitz, K.A, Bubunenko, M, Court, D, Stec, B, Roberts, M.F. | Deposit date: | 2007-06-27 | Release date: | 2007-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structure of the R184A mutant of the inositol monophosphatase encoded by suhB and implications for its functional interactions in Escherichia coli. J.Biol.Chem., 282, 2007
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3QW2
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![BU of 3qw2 by Molmil](/molmil-images/mine/3qw2) | L-myo-inositol 1-phosphate synthase from Archaeoglobus mutant N255A | Descriptor: | GLYCEROL, Myo-inositol-1-phosphate synthase (Ino1), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Neelon, K, Roberts, M.F, Stec, B. | Deposit date: | 2011-02-26 | Release date: | 2012-01-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal structure of a trapped catalytic intermediate suggests that forced atomic proximity drives the catalysis of mIPS. Biophys.J., 101, 2011
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1U1I
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![BU of 1u1i by Molmil](/molmil-images/mine/1u1i) | Myo-inositol phosphate synthase mIPS from A. fulgidus | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, POTASSIUM ION, ... | Authors: | Stieglitz, K.A, Yang, H, Roberts, M.F, Stec, B. | Deposit date: | 2004-07-15 | Release date: | 2004-08-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Reaching for Mechanistic Consensus Across Life Kingdoms: Structure and Insights into Catalysis of the myo-Inositol-1-phosphate Synthase (mIPS) from Archaeoglobus fulgidus Biochemistry, 44, 2005
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1U1U
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![BU of 1u1u by Molmil](/molmil-images/mine/1u1u) | A. thaliana cobalamine independent methionine synthase | Descriptor: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, SULFATE ION, ZINC ION | Authors: | Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R. | Deposit date: | 2004-07-16 | Release date: | 2004-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate J.Biol.Chem., 279, 2004
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2XUZ
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![BU of 2xuz by Molmil](/molmil-images/mine/2xuz) | Crystal structure of the triscatecholate siderophore binding protein FeuA from Bacillus subtilis complexed with Ferri-Enterobactin | Descriptor: | DI(HYDROXYETHYL)ETHER, FE (III) ION, IRON-UPTAKE SYSTEM-BINDING PROTEIN, ... | Authors: | Peuckert, F, Miethke, M, Schwoerer, C.J, Albrecht, A.G, Oberthuer, M, Marahiel, M.A. | Deposit date: | 2010-10-22 | Release date: | 2011-08-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Siderophore Binding Protein Feua Shows Limited Promiscuity Toward Exogenous Triscatecholates Chem.Biol., 18, 2011
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2XV1
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![BU of 2xv1 by Molmil](/molmil-images/mine/2xv1) | Crystal structure of the triscatecholate siderophore binding protein FeuA from Bacillus subtilis complexed with Ferric MECAM | Descriptor: | DI(HYDROXYETHYL)ETHER, FE (III) ION, IRON-UPTAKE SYSTEM-BINDING PROTEIN, ... | Authors: | Peuckert, F, Miethke, M, Schwoerer, C.J, Albrecht, A.G, Oberthuer, M, Marahiel, M.A. | Deposit date: | 2010-10-22 | Release date: | 2011-08-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The Siderophore Binding Protein Feua Shows Limited Promiscuity Toward Exogenous Triscatecholates Chem.Biol., 18, 2011
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3QVS
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![BU of 3qvs by Molmil](/molmil-images/mine/3qvs) | L-myo-inositol 1-phosphate synthase from Archaeoglobus fulgidus wild type | Descriptor: | GLYCEROL, Myo-inositol-1-phosphate synthase (Ino1), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Neelon, K, Roberts, M.F, Stec, B. | Deposit date: | 2011-02-25 | Release date: | 2012-01-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of a trapped catalytic intermediate suggests that forced atomic proximity drives the catalysis of mIPS. Biophys.J., 101, 2011
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1U1H
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![BU of 1u1h by Molmil](/molmil-images/mine/1u1h) | A. thaliana cobalamine independent methionine synthase | Descriptor: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, METHIONINE, SULFATE ION, ... | Authors: | Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R. | Deposit date: | 2004-07-15 | Release date: | 2004-09-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate J.Biol.Chem., 279, 2004
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1U22
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![BU of 1u22 by Molmil](/molmil-images/mine/1u22) | A. thaliana cobalamine independent methionine synthase | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, ... | Authors: | Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R. | Deposit date: | 2004-07-16 | Release date: | 2004-09-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate J.Biol.Chem., 279, 2004
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1U1J
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![BU of 1u1j by Molmil](/molmil-images/mine/1u1j) | A. thaliana cobalamine independent methionine synthase | Descriptor: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, METHIONINE, ... | Authors: | Ferrer, J.-L, Ravanel, S, Robert, M, Dumas, R. | Deposit date: | 2004-07-15 | Release date: | 2004-09-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate J.Biol.Chem., 279, 2004
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3V16
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![BU of 3v16 by Molmil](/molmil-images/mine/3v16) | An intramolecular pi-cation latch in phosphatidylinositol-specific phospholipase C from S.aureus controls substrate access to the active site | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, CHLORIDE ION | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | Deposit date: | 2011-12-09 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop Biochemistry, 51, 2012
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1LBY
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![BU of 1lby by Molmil](/molmil-images/mine/1lby) | Crystal Structure of a complex (P32 crystal form) of dual activity FBPase/IMPase (AF2372) from Archaeoglobus fulgidus with 3 Manganese ions, Fructose-6-Phosphate, and Phosphate ion | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, MANGANESE (II) ION, PHOSPHATE ION, ... | Authors: | Stieglitz, K.A, Johnson, K.A, Yang, H, Roberts, M.F, Seaton, B.A, Head, J.F, Stec, B. | Deposit date: | 2002-04-04 | Release date: | 2002-05-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop. J.Biol.Chem., 277, 2002
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4F2T
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![BU of 4f2t by Molmil](/molmil-images/mine/4f2t) | Modulation of S.aureus Phosphatidylinositol-Specific Phospholipase C Membrane Binding. | Descriptor: | 1-phosphatidylinositol phosphodiesterase, ACETATE ION | Authors: | Cheng, J, Goldstein, R, Stec, B, Gershenson, A, Roberts, M.F. | Deposit date: | 2012-05-08 | Release date: | 2012-12-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity. J.Biol.Chem., 287, 2012
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4F2B
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![BU of 4f2b by Molmil](/molmil-images/mine/4f2b) | Modulation of S.Aureus Phosphatidylinositol-Specific Phospholipase C Membrane Binding | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase | Authors: | Cheng, J, Goldstein, R, Stec, B, Gershenson, A, Roberts, M.F. | Deposit date: | 2012-05-07 | Release date: | 2012-12-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity. J.Biol.Chem., 287, 2012
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4AXH
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![BU of 4axh by Molmil](/molmil-images/mine/4axh) | Structure and mechanism of the first inverting alkylsulfatase specific for secondary alkylsulfatases | Descriptor: | SEC-ALKYLSULFATASE, SULFATE ION, ZINC ION | Authors: | Knaus, T, Schober, M, Faber, K, Macheroux, P, Wagner, U.G. | Deposit date: | 2012-06-13 | Release date: | 2012-12-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and Mechanism of an Inverting Alkylsulfatase from Pseudomonas Sp. Dsm6611 Specific for Secondary Alkylsulfates. FEBS J., 279, 2012
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3QVW
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![BU of 3qvw by Molmil](/molmil-images/mine/3qvw) | L-myo-inositol 1-phosphate synthase from Archaeoglobus fulgidus mutant K278A | Descriptor: | GLYCEROL, Myo-inositol-1-phosphate synthase (Ino1), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Neelon, K, Roberts, M.F, Stec, B. | Deposit date: | 2011-02-26 | Release date: | 2012-01-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a trapped catalytic intermediate suggests that forced atomic proximity drives the catalysis of mIPS. Biophys.J., 101, 2011
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1LBV
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![BU of 1lbv by Molmil](/molmil-images/mine/1lbv) | Crystal Structure of apo-form (P21) of dual activity FBPase/IMPase (AF2372) from Archaeoglobus fulgidus | Descriptor: | fructose 1,6-bisphosphatase/inositol monophosphatase | Authors: | Stieglitz, K.A, Johnson, K.A, Yang, H, Roberts, M.F, Seaton, B.A, Head, J.F, Stec, B. | Deposit date: | 2002-04-04 | Release date: | 2002-05-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a dual activity IMPase/FBPase (AF2372) from Archaeoglobus fulgidus. The story of a mobile loop. J.Biol.Chem., 277, 2002
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