4H56
 
 | | Crystal structure of the Clostridium perfringens NetB toxin in the membrane inserted form | | 分子名称: | Necrotic enteritis toxin B | | 著者 | Savva, C.G, Fernandes da Costa, S.P, Bokori-Brown, M, Naylor, C, Cole, A.R, Moss, D.S, Titball, R.W, Basak, A.K. | | 登録日 | 2012-09-18 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens.
J.Biol.Chem., 288, 2013
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5E7W
 | | X-ray Structure of Human Recombinant 2Zn insulin at 0.92 Angstrom | | 分子名称: | ACETATE ION, Insulin, N-PROPANOL, ... | | 著者 | Lisgarten, D.R, Naylor, C.E, Palmer, R.A, Lobley, C.M.C. | | 登録日 | 2015-10-13 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (0.9519 Å) | | 主引用文献 | Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K.
Chem Cent J, 11, 2017
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1H9B
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5HVD
 | | Full length Open-form Sodium Channel NavMs I218C | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Sula, A, Booker, J.E, Naylor, C.E, Wallace, B.A. | | 登録日 | 2016-01-28 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The complete structure of an activated open sodium channel.
Nat Commun, 8, 2017
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1H9A
 | | COMPLEX OF ACTIVE MUTANT (Q365->C) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM L. MESENTEROIDES WITH COENZYME NADP | | 分子名称: | GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION | | 著者 | Adams, M.J, Naylor, C.E, Gover, S. | | 登録日 | 2001-03-06 | | 公開日 | 2001-05-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Nadp+ and Nad+ Binding to the Dual Coenzyme Specific Enzyme Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: Different Interdomain Hinge Angles are Seen in Different Binary and Ternary Complexes
Acta Crystallogr.,Sect.D, 57, 2001
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1H93
 | | ACTIVE MUTANT (S215->C) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES | | 分子名称: | CALCIUM ION, GLUCOSE 6-PHOSPHATE 1-DEHYDROGENASE, GLYCEROL | | 著者 | Adams, M.J, Naylor, C.E, Gover, S. | | 登録日 | 2001-02-23 | | 公開日 | 2001-05-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Nadp+ and Nad+ Binding to the Dual Coenzyme Specific Enzyme Leuconostoc Mesenteroides Glucose 6-Phosphate Dehydrogenase: Different Interdomain Hinge Angles are Seen in Different Binary and Ternary Complexes
Acta Crystallogr.,Sect.D, 57, 2001
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5HVX
 | | Full length Wild-Type Open-form Sodium Channel NavMs | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DODECAETHYLENE GLYCOL, ... | | 著者 | Sula, A, Booker, J.E, Naylor, C.E, Wallace, B.A. | | 登録日 | 2016-01-28 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The complete structure of an activated open sodium channel.
Nat Commun, 8, 2017
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1H94
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5GAQ
 | | Cryo-EM structure of the Lysenin Pore | | 分子名称: | Lysenin | | 著者 | Savva, C.G, Bokori-Brown, M, Martin, T.G, Titball, R.W, Naylor, C.E, Basak, A.K. | | 登録日 | 2016-01-05 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein
Nat Commun, 7, 2016
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3ZJZ
 | | Open-form NavMS Sodium Channel Pore (with C-terminal Domain) | | 分子名称: | DODECAETHYLENE GLYCOL, HEGA-10, ION TRANSPORT PROTEIN, ... | | 著者 | Bagneris, C, Naylor, C.E, Wallace, B.A. | | 登録日 | 2013-01-21 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Role of the C-Terminal Domain in the Structure and Function of Tetrameric Sodium Channels.
Nat.Commun., 4, 2013
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3ZIX
 | | Clostridium perfringens Enterotoxin with the N-terminal 37 residues deleted | | 分子名称: | HEAT-LABILE ENTEROTOXIN B CHAIN, HEXAETHYLENE GLYCOL | | 著者 | Yelland, T, Naylor, C.E, Savva, C.G, Basak, A.K. | | 登録日 | 2013-01-14 | | 公開日 | 2014-01-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of a C. Perfringens Enterotoxin Mutant in Complex with a Modified Claudin-2 Extracellular Loop 2
J.Mol.Biol., 426, 2014
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3ZIW
 | | Clostridium perfringens enterotoxin, D48A mutation and N-terminal 37 residues deleted | | 分子名称: | HEAT-LABILE ENTEROTOXIN B CHAIN, HEXAETHYLENE GLYCOL | | 著者 | Yelland, T, Naylor, C.E, Savva, C.G, Basak, A.K. | | 登録日 | 2013-01-14 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of a C. Perfringens Enterotoxin Mutant in Complex with a Modified Claudin-2 Extracellular Loop 2
J.Mol.Biol., 426, 2014
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2DPG
 | | COMPLEX OF INACTIVE MUTANT (H240->N) OF GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM LEUCONOSTOC MESENTEROIDES WITH NADP+ | | 分子名称: | GLUCOSE 6-PHOSPHATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Adams, M.J, Naylor, C.E, Paludin, S, Gover, S. | | 登録日 | 1998-04-17 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | On the mechanism of the reaction catalyzed by glucose 6-phosphate dehydrogenase.
Biochemistry, 37, 1998
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4P2Z
 | | Structure of NavMS T207A/F214A | | 分子名称: | DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... | | 著者 | Bagneris, C, Naylor, C.E, Wallace, B.A. | | 登録日 | 2014-03-05 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4P30
 | | Structure of NavMS mutant in presence of PI1 compound | | 分子名称: | DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... | | 著者 | Bagneris, C, Naylor, C.E, Wallace, B.A. | | 登録日 | 2014-03-05 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1V1P
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3ZJX
 | | Clostridium perfringens epsilon toxin mutant H149A bound to octyl glucoside | | 分子名称: | EPSILON-TOXIN, PHOSPHATE ION, octyl beta-D-glucopyranoside | | 著者 | Bokori-Brown, M, Kokkinidou, M.C, Savva, C.G, Fernandes da Costa, S.P, Naylor, C.E, Cole, A.R, Basak, A.K, Titball, R.W. | | 登録日 | 2013-01-20 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Clostridium Perfringens Epsilon Toxin H149A Mutant as a Platform for Receptor Binding Studies.
Protein Sci., 22, 2013
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2Y1Z
 | | Human alphaB Crystallin ACD R120G | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ALPHA-CRYSTALLIN B CHAIN | | 著者 | Clark, A.R, Bagneris, C, Naylor, C.E, Keep, N.H, Slingsby, C. | | 登録日 | 2010-12-10 | | 公開日 | 2011-03-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of R120G Disease Mutant of Human Alphab-Crystallin Domain Dimer Shows Closure of a Groove
J.Mol.Biol., 408, 2011
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4ACV
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2WY6
 | | Clostridium perfringens alpha-toxin strain NCTC8237 mutant T74I | | 分子名称: | CADMIUM ION, CALCIUM ION, GLYCEROL, ... | | 著者 | Vachieri, S.G, Naylor, C.E, Basak, A.K. | | 登録日 | 2009-11-12 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
Acta Crystallogr.,Sect.D, 66, 2011
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2WXU
 | | Clostridium perfringens alpha-toxin strain NCTC8237 mutant T74I | | 分子名称: | CADMIUM ION, CALCIUM ION, PHOSPHOLIPASE C, ... | | 著者 | Vachieri, S.G, Naylor, C.E, Basak, A.K. | | 登録日 | 2009-11-10 | | 公開日 | 2009-11-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
Acta Crystallogr.,Sect.D, 66, 2010
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2WXT
 | | Clostridium perfringens alpha-toxin strain NCTC8237 | | 分子名称: | CADMIUM ION, CALCIUM ION, PHOSPHOLIPASE C, ... | | 著者 | Justin, N, Naylor, C.E, Basak, A.K. | | 登録日 | 2009-11-10 | | 公開日 | 2009-11-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
Acta Crystallogr.,Sect.D, 66, 2010
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1PGP
 | | CRYSTALLOGRAPHIC STUDY OF COENZYME, COENZYME ANALOGUE AND SUBSTRATE BINDING IN 6-PHOSPHOGLUCONATE DEHYDROGENASE: IMPLICATIONS FOR NADP SPECIFICITY AND THE ENZYME MECHANISM | | 分子名称: | 6-PHOSPHOGLUCONATE DEHYDROGENASE, 6-PHOSPHOGLUCONIC ACID, SULFATE ION | | 著者 | Adams, M.J, Phillips, C, Gover, S, Naylor, C.E. | | 登録日 | 1994-07-18 | | 公開日 | 1995-02-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystallographic study of coenzyme, coenzyme analogue and substrate binding in 6-phosphogluconate dehydrogenase: implications for NADP specificity and the enzyme mechanism.
Structure, 2, 1994
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2YGT
 | | Clostridium perfringens delta-toxin | | 分子名称: | DELTA TOXIN, GLYCEROL, IMIDAZOLE, ... | | 著者 | Huyet, J, Naylor, C.E, Gibert, M, Popoff, M.R, Basak, A.K. | | 登録日 | 2011-04-20 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Insights Into Clostridium Perfringens Delta Toxin Pore Formation.
Plos One, 8, 2013
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2YHJ
 | | Clostridium perfringens Enterotoxin at 4.0 Angstrom Resolution | | 分子名称: | HEAT-LABILE ENTEROTOXIN B CHAIN | | 著者 | Briggs, D.C, Naylor, C.E, Smedley III, J.G, McClane, B.A, Basak, A.K. | | 登録日 | 2011-05-03 | | 公開日 | 2011-08-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Structure of the Food-Poisoning Clostridium Perfringens Enterotoxin Reveals Similarity to the Aerolysin-Like Pore-Forming Toxins
J.Mol.Biol., 413, 2011
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