5D85
 
 | | Staphyloferrin B precursor biosynthetic enzyme SbnA bound to aminoacrylate intermediate | | 分子名称: | 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, CITRATE ANION, GLYCEROL, ... | | 著者 | Kobylarz, M.J, Grigg, J.C, Liu, Y, Lee, M.S.F, Heinrichs, D.E, Murphy, M.E.P. | | 登録日 | 2015-08-15 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis.
Biochemistry, 55, 2016
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2ITF
 | | Crystal structure IsdA NEAT domain from Staphylococcus aureus with heme bound | | 分子名称: | Iron-regulated surface determinant protein A, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Grigg, J.C, Vermeiren, C.L, Heinrichs, D.E, Murphy, M.E. | | 登録日 | 2006-10-19 | | 公開日 | 2006-12-26 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Haem recognition by a Staphylococcus aureus NEAT domain.
Mol.Microbiol., 63, 2007
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2ITE
 | | Crystal structure of the IsdA NEAT domain from Staphylococcus aureus | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Iron-regulated surface determinant protein A | | 著者 | Grigg, J.C, Vermeiren, C.L, Heinrichs, D.E, Murphy, M.E. | | 登録日 | 2006-10-19 | | 公開日 | 2006-12-26 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Haem recognition by a Staphylococcus aureus NEAT domain.
Mol.Microbiol., 63, 2007
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3E2C
 | | Escherichia coli Bacterioferritin Mutant E128R/E135R | | 分子名称: | 1,2-ETHANEDIOL, Bacterioferritin, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Wong, S.G, Tom-Yew, S.A.L, Lewin, A, Le Brun, N.E, Moore, G.R, Murphy, M.E.P, Mauk, A.G. | | 登録日 | 2008-08-05 | | 公開日 | 2009-05-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and Mechanistic Studies of a Stabilized Subunit Dimer Variant of Escherichia coli Bacterioferritin Identify Residues Required for Core Formation.
J.Biol.Chem., 284, 2009
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5D2R
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4R5J
 | | Crystal structure of the DnaK C-terminus (Dnak-SBD-A) | | 分子名称: | CALCIUM ION, Chaperone protein DnaK, PHOSPHATE ION | | 著者 | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | | 登録日 | 2014-08-21 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.361 Å) | | 主引用文献 | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket.
Acs Chem.Biol., 9, 2014
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4R5L
 | | Crystal structure of the DnaK C-terminus (Dnak-SBD-C) | | 分子名称: | CALCIUM ION, Chaperone protein DnaK, PHOSPHATE ION, ... | | 著者 | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | | 登録日 | 2014-08-21 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.9701 Å) | | 主引用文献 | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket.
Acs Chem.Biol., 9, 2014
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3EIX
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3EIW
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8G64
 | | Heme-bound flavodoxin FldH from Fusobacterium nucleatum | | 分子名称: | FLAVIN MONONUCLEOTIDE, Flavodoxin, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Chan, A.C, Wolthers, K.R, Murphy, M.E. | | 登録日 | 2023-02-14 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A new member of the flavodoxin superfamily from Fusobacterium nucleatum that functions in heme trafficking and reduction of anaerobilin.
J.Biol.Chem., 299, 2023
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4R5G
 | | Crystal structure of the DnaK C-terminus with the inhibitor PET-16 | | 分子名称: | Chaperone protein DnaK, triphenyl(phenylethynyl)phosphonium | | 著者 | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | | 登録日 | 2014-08-21 | | 公開日 | 2014-09-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.4501 Å) | | 主引用文献 | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket.
Acs Chem.Biol., 9, 2014
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4R5I
 | | Crystal structure of the DnaK C-terminus with the substrate peptide NRLLLTG | | 分子名称: | Chaperone protein DnaK, HSP70/DnaK Substrate Peptide: NRLLLTG, PHOSPHATE ION, ... | | 著者 | Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. | | 登録日 | 2014-08-21 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9702 Å) | | 主引用文献 | Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket.
Acs Chem.Biol., 9, 2014
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8GKD
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8GLD
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5VMM
 | | Staphylococcus aureus IsdB bound to human hemoglobin | | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated cell wall-anchored protein, ... | | 著者 | Bowden, C.F, Chan, A.C, Murphy, M.E. | | 登録日 | 2017-04-27 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structure-function analyses reveal key features in Staphylococcus aureus IsdB-associated unfolding of the heme-binding pocket of human hemoglobin.
J. Biol. Chem., 293, 2018
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8T4C
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4TV6
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4TV5
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5VN5
 | | Crystal structure of LigY from Sphingobium sp. strain SYK-6 | | 分子名称: | 2,2',3-trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl meta-cleavage compound hydrolase, CHLORIDE ION, ZINC ION | | 著者 | Kuatsjah, E, Chan, A.C.K, Kobylarz, M.J, Murphy, M.E.P, Eltis, L.D. | | 登録日 | 2017-04-28 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The bacterialmeta-cleavage hydrolase LigY belongs to the amidohydrolase superfamily, not to the alpha / beta-hydrolase superfamily.
J. Biol. Chem., 292, 2017
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4U3G
 | | Crystal structure of Escherichia coli bacterioferritin mutant D132F | | 分子名称: | Bacterioferritin, SULFATE ION | | 著者 | Wong, S.G, Grigg, J.C, Le Brun, N.E, Moore, G.R, Murphy, M.E.P, Mauk, A.G. | | 登録日 | 2014-07-21 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The B-type Channel Is a Major Route for Iron Entry into the Ferroxidase Center and Central Cavity of Bacterioferritin.
J.Biol.Chem., 290, 2015
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1VFR
 | | THE MAJOR NAD(P)H:FMN OXIDOREDUCTASE FROM VIBRIO FISCHERI | | 分子名称: | FLAVIN MONONUCLEOTIDE, NAD(P)H:FMN OXIDOREDUCTASE | | 著者 | Koike, H, Sasaki, H, Kobori, T, Zenno, S, Saigo, K, Murphy, M.E.P, Adman, E.T, Tanokura, M. | | 登録日 | 1998-01-09 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | 1.8 A crystal structure of the major NAD(P)H:FMN oxidoreductase of a bioluminescent bacterium, Vibrio fischeri: overall structure, cofactor and substrate-analog binding, and comparison with related flavoproteins.
J.Mol.Biol., 280, 1998
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7JU2
 | | Crystal structure of the monomeric ETV6 PNT domain | | 分子名称: | FORMIC ACID, Transcription factor ETV6 | | 著者 | Gerak, C.A.N, Kolesnikov, M, Murphy, M.E.P, McIntosh, L.P. | | 登録日 | 2020-08-19 | | 公開日 | 2021-01-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85002184 Å) | | 主引用文献 | Biophysical characterization of the ETV6 PNT domain polymerization interfaces.
J.Biol.Chem., 296, 2021
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5YTL
 | | Crystal structure of Geobacillus thermodenitrificans copper-containing nitrite reductase determined with an anaerobically manipulated crystal | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, ... | | 著者 | Fukuda, Y, Matsusaki, T, Tse, K.M, Mizohata, E, Murphy, M.E.P, Inoue, T. | | 登録日 | 2017-11-19 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | | 主引用文献 | Crystallographic study of dioxygen chemistry in a copper-containing nitrite reductase from Geobacillus thermodenitrificans.
Acta Crystallogr D Struct Biol, 74, 2018
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8D27
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5IXG
 | | Crystal Structure of Burkholderia cenocepacia BcnB | | 分子名称: | (2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL TRIHYDROGEN DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, YceI | | 著者 | Loutet, S.A, Murphy, M.E.P. | | 登録日 | 2016-03-23 | | 公開日 | 2017-03-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance.
MBio, 8, 2017
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