1PZK
 
 | | Cholera Toxin B-Pentamer Complexed With N-Acyl Phenyl Galactoside 9h | | 分子名称: | Cholera Toxin B Subunit, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-(2-THIOPHEN-2-YL-ACETYLAMINO)-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE | | 著者 | Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J. | | 登録日 | 2003-07-11 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
|
|
1PZJ
 | | Cholera Toxin B-Pentamer Complexed With Nitrophenyl Galactoside 5 | | 分子名称: | Cholera Toxin B Subunit, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-NITRO-5-(GALACTOPYRANOSYL)-ALPHA-BENZAMIDE, N-{3-[4-(3-AMINO-PROPYL)-PIPERAZIN-1-YL]-PROPYL}-3-NITRO-5-(GALACTOPYRANOSYL)-BETA-BENZAMIDE | | 著者 | Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J. | | 登録日 | 2003-07-11 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
|
|
1PZI
 | | Heat-Labile Enterotoxin B-Pentamer Complexed With Nitrophenyl Galactoside 2a | | 分子名称: | Heat-labile Enterotoxin B subunit, N-(2-MORPHOLIN-4-YL-1-MORPHOLIN-4-YLMETHYL-ETHYL)-3-NITRO-5-(3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-2-YLOXY)-BENZAMIDE | | 著者 | Mitchell, D.D, Pickens, J.C, Korotkov, K, Fan, E, Hol, W.G.J. | | 登録日 | 2003-07-11 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
Bioorg.Med.Chem., 12, 2004
|
|
1E2O
 | | CATALYTIC DOMAIN FROM DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE | | 分子名称: | DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE, SULFATE ION | | 著者 | Knapp, J.E, Mitchell, D.T, Yazdi, M.A, Ernst, S.R, Reed, L.J, Hackert, M.L. | | 登録日 | 1998-05-26 | | 公開日 | 1998-12-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of the truncated cubic core component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex.
J.Mol.Biol., 280, 1998
|
|
1AW7
 | | Q136A MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | | 分子名称: | TOXIC SHOCK SYNDROME TOXIN-1 | | 著者 | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | | 登録日 | 1997-10-11 | | 公開日 | 1998-10-28 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Biochemistry, 37, 1998
|
|
8AGM
 | | Limonene epoxide low pH soak of epoxide hydrolase from metagenomic source ch65 | | 分子名称: | 1,2-ETHANEDIOL, Alpha/beta epoxide hydrolase, CHLORIDE ION, ... | | 著者 | Isupov, M.N, De Rose, S.A, Mitchell, D, Littlechild, J.A. | | 登録日 | 2022-07-20 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.966 Å) | | 主引用文献 | Complexes of epoxide hydrolase from metagenomic source ch65
To Be Published
|
|
8AGS
 | | Cyclohexane epoxide soak of epoxide hydrolase from metagenomic source ch65 resulting in halogenated compound in the active site | | 分子名称: | 1,2-ETHANEDIOL, 2-CHLOROPHENOL, Alpha/beta epoxide hydrolase, ... | | 著者 | Isupov, M.N, De Rose, S.A, Mitchell, D, Littlechild, J.A. | | 登録日 | 2022-07-20 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Complexes of epoxide hydrolase from metagenomic source ch65
To Be Published
|
|
8AGN
 | | Cyclohexane epoxide low pH soak of epoxide hydrolase from metagenomic source ch65 | | 分子名称: | (1R,6S)-7-oxabicyclo[4.1.0]heptane, 1,2-ETHANEDIOL, Alpha/beta epoxide hydrolase, ... | | 著者 | Isupov, M.N, De Rose, S.A, Mitchell, D, Littlechild, J.A. | | 登録日 | 2022-07-20 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.957 Å) | | 主引用文献 | Complexes of epoxide hydrolase from metagenomic source ch65
To Be Published
|
|
8AGP
 | | Halogenated product of limonene epoxide turnover by epoxide hydrolase from metagenomic source ch65 | | 分子名称: | (1~{S},2~{S},4~{R})-2-chloranyl-1-methyl-4-prop-1-en-2-yl-cyclohexan-1-ol, 1,2-ETHANEDIOL, Alpha/beta epoxide hydrolase, ... | | 著者 | Isupov, M.N, De Rose, S.A, Mitchell, D, Littlechild, J.A. | | 登録日 | 2022-07-20 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Complexes of epoxide hydrolase from metagenomic source ch65
To Be Published
|
|
3C1Q
 | | The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae | | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Abendroth, J, Mitchell, D.D, Korotkov, K.V, Kreeger, A, Hol, W.G.J. | | 登録日 | 2008-01-24 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The three-dimensional structure of the cytoplasmic domains of EpsF from the type 2 secretion system of Vibrio cholerae
J.Struct.Biol., 166, 2009
|
|
7Q9Z
 | | Crystal structure of Chromobacterium violaceum aminotransferase in complex with PLP-pyruvate adduct | | 分子名称: | (3E)-4-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}-2-oxobut-3-enoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Isupov, M.N, Mitchell, D, Sayer, C, Littlechild, J.A. | | 登録日 | 2021-11-15 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Aminotransferase from Chromobacterium violaceum in complex with PLP-pyruvate adduct.
To Be Published
|
|
7Q9X
 | | Crystal structure of Chromobacterium violaceum aminotransferase in complex with PLP-pyruvate adduct | | 分子名称: | (3E)-4-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}-2-oxobut-3-enoic acid, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Isupov, M.N, Mitchell, D, Sayer, C, Littlechild, J.A. | | 登録日 | 2021-11-15 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Aminotransferase from Chromobacterium violaceum in complex with PLP-pyruvate adduct.
To Be Published
|
|
5JPL
 | | LP2006, a handcuff-topology lasso peptide antibiotic | | 分子名称: | Uncharacterized protein | | 著者 | Tietz, J.I, Schwalen, C.J, Blair, P.M, Zakai, U.I, Mitchell, D.A. | | 登録日 | 2016-05-03 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A new genome-mining tool redefines the lasso peptide biosynthetic landscape.
Nat. Chem. Biol., 13, 2017
|
|
6F1H
 | | C1rC1s complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-galactopyranose-(1-4)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Almitairi, J.O.M, Venkatraman Girija, U, Furze, C.M, Simpson-Gray, X, Badakshi, F, Marshall, J.E, Mitchell, D.A, Moody, P.C.E, Wallis, R. | | 登録日 | 2017-11-22 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6F1C
 | | C1rC1s complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C1r subcomponent, ... | | 著者 | Almitairi, J.O.M, Venkatraman Girija, U, Furze, C.M, Simpson-Gray, X, Badakshi, F, Marshall, J.E, Mitchell, D.A, Moody, P.C.E, Wallis, R. | | 登録日 | 2017-11-21 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6F39
 | | C1r homodimer CUB1-EGF-CUB2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C1r subcomponent, ... | | 著者 | Almitairi, J.O.M, Venkatraman Girija, U, Furze, C.M, Simpson-Gray, X, Badakshi, F, Marshall, J.E, Mitchell, D.A, Moody, P.C.E, Wallis, R. | | 登録日 | 2017-11-28 | | 公開日 | 2018-01-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (5.801 Å) | | 主引用文献 | Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
5TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1: ORTHORHOMBIC P222(1) CRYSTAL FORM | | 分子名称: | TOXIC SHOCK SYNDROME TOXIN-1 | | 著者 | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | 登録日 | 1996-12-11 | | 公開日 | 1997-12-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
|
|
4TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1: TETRAGONAL P4(1)2(1)2 CRYSTAL FORM | | 分子名称: | TOXIC SHOCK SYNDROME TOXIN-1, ZINC ION | | 著者 | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | 登録日 | 1996-12-11 | | 公開日 | 1997-12-24 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
|
|
3TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1 TETRAMUTANT, P2(1) CRYSTAL FORM | | 分子名称: | TOXIC SHOCK SYNDROME TOXIN-1 | | 著者 | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | 登録日 | 1996-12-11 | | 公開日 | 1997-12-24 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
|
|
2TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1 FROM STAPHYLOCOCCUS AUREUS: ORTHORHOMBICC222(1) CRYSTAL FORM | | 分子名称: | TOXIC SHOCK SYNDROME TOXIN-1 | | 著者 | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | 登録日 | 1996-12-04 | | 公開日 | 1997-12-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
|
|
1TS5
 | | I140T MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | | 分子名称: | TOXIC SHOCK SYNDROME TOXIN-1 | | 著者 | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | | 登録日 | 1997-10-10 | | 公開日 | 1998-12-16 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Biochemistry, 37, 1998
|
|
6F1D
 | | CUB2 domain of C1r | | 分子名称: | CALCIUM ION, Complement C1r subcomponent, SODIUM ION | | 著者 | Almitairi, J.O.M, Venkatraman Girija, U, Furze, C.M, Simpson-Gray, X, Badakshi, F, Marshall, J.E, Mitchell, D.A, Moody, P.C.E, Wallis, R. | | 登録日 | 2017-11-21 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of the C1r-C1s interaction of the C1 complex of complement activation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
1HLB
 | |
1TS4
 | | Q139K MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | | 分子名称: | TOXIC SHOCK SYNDROME TOXIN-1 | | 著者 | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | | 登録日 | 1997-10-10 | | 公開日 | 1998-12-16 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Biochemistry, 37, 1998
|
|
7JS6
 | |
