7GSR
 
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7GS7
 | | PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000621a | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(1,2,3-thiadiazol-4-yl)phenyl ethylcarbamate, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Mehlman, T, Ginn, H.M, Keedy, D.A. | | 登録日 | 2024-01-03 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
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7GSY
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7GT5
 | | PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOOA000529a | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1, methyl [(3R,4S)-3-ethyl-4-hydroxy-1,1-dioxo-3,4-dihydro-1lambda~6~,2-benzothiazin-2(1H)-yl]acetate | | 著者 | Mehlman, T, Ginn, H.M, Keedy, D.A. | | 登録日 | 2024-01-03 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
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7GTT
 | | PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000148a | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-(3,4-dihydroquinoline-1(2H)-carbothioyl)propanamide, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Mehlman, T, Ginn, H.M, Keedy, D.A. | | 登録日 | 2024-01-03 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
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7GSA
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7GSB
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4BLF
 | | Variable internal flexibility characterizes the helical capsid formed by Agrobacterium VirE2 protein on single-stranded DNA. | | 分子名称: | SINGLE-STRAND DNA-BINDING PROTEIN | | 著者 | Bharat, T.A.M, Zbaida, D, Eisenstein, M, Frankenstein, Z, Mehlman, T, Weiner, L, Sorzano, C.O.S, Barak, Y, Albeck, S, Briggs, J.A.G, Wolf, S.G, Elbaum, M. | | 登録日 | 2013-05-02 | | 公開日 | 2013-06-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (20 Å) | | 主引用文献 | Variable Internal Flexibility Characterizes the Helical Capsid Formed by Agrobacterium Vire2 Protein on Single-Stranded DNA.
Structure, 21, 2013
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9CYO
 | | Crystal structure of wild-type human PTP1B (PTPN1) at room temperature (298 K) | | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Ebrahim, A, Perdikari, A, Woods, V.A, Lawler, K, Bounds, R, Singh, N.I, Mehlman, T, Riley, B.T, Sharma, S, Morris, J.W, Keogh, J.M, Henning, E, Smith, M, Farooqi, I.S, Keedy, D.A. | | 登録日 | 2024-08-02 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy
Biorxiv, 2024
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9CYP
 | | Crystal structure of I19V mutant human PTP1B (PTPN1) at room temperature (298 K) | | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Ebrahim, A, Perdikari, A, Woods, V.A, Lawler, K, Bounds, R, Singh, N.I, Mehlman, T, Riley, B.T, Sharma, S, Morris, J.W, Keogh, J.M, Henning, E, Smith, M, Farooqi, I.S, Keedy, D.A. | | 登録日 | 2024-08-02 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy
Biorxiv, 2024
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9CYQ
 | | Crystal structure of Q78R mutant human PTP1B (PTPN1) at room temperature (298 K) | | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Ebrahim, A, Perdikari, A, Woods, V.A, Lawler, K, Bounds, R, Singh, N.I, Mehlman, T, Riley, B.T, Sharma, S, Morris, J.W, Keogh, J.M, Henning, E, Smith, M, Farooqi, I.S, Keedy, D.A. | | 登録日 | 2024-08-02 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy
Biorxiv, 2024
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9CYR
 | | Crystal structure of D245G mutant human PTP1B (PTPN1) at room temperature (298 K) | | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Ebrahim, A, Perdikari, A, Woods, V.A, Lawler, K, Bounds, R, Singh, N.I, Mehlman, T, Riley, B.T, Sharma, S, Morris, J.W, Keogh, J.M, Henning, E, Smith, M, Farooqi, I.S, Keedy, D.A. | | 登録日 | 2024-08-02 | | 公開日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy
Biorxiv, 2024
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