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PDB: 2 件

8FQT
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BU of 8fqt by Molmil
Apo ADC-219 beta-lactamase
分子名称: Beta-lactamase, PHOSPHATE ION
著者Powers, R.A, Wallar, B.J, June, C.M, Maurer, O.L.
登録日2023-01-06
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Synthesis of a Novel Boronic Acid Transition State Inhibitor, MB076: A Heterocyclic Triazole Effectively Inhibits Acinetobacter -Derived Cephalosporinase Variants with an Expanded-Substrate Spectrum.
J.Med.Chem., 66, 2023
8FQU
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BU of 8fqu by Molmil
ADC-219 in complex with boronic acid transition state inhibitor MB076
分子名称: 1-[(2R)-2-{2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]acetamido}-2-boronoethyl]-1H-1,2,3-triazole-4-carboxylic acid, Beta-lactamase, DIMETHYL SULFOXIDE
著者Powers, R.A, Wallar, B.J, June, C.M, Maurer, O.L.
登録日2023-01-06
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Synthesis of a Novel Boronic Acid Transition State Inhibitor, MB076: A Heterocyclic Triazole Effectively Inhibits Acinetobacter -Derived Cephalosporinase Variants with an Expanded-Substrate Spectrum.
J.Med.Chem., 66, 2023

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件を2024-07-24に公開中

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