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PDB: 3 results

7MGS
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BU of 7mgs by Molmil
SARS-CoV-2 main protease in complex with N-terminal autoprocessing substrate
Descriptor: 3C-like proteinase, CHLORIDE ION, SER-ALA-VAL-LEU-GLN-SER-GLY-PHE
Authors:MacDonald, E.A, Windsor, I.W, Hinshaw, S.M.
Deposit date:2021-04-13
Release date:2021-06-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Recognition of Divergent Viral Substrates by the SARS-CoV-2 Main Protease.
Acs Infect Dis., 7, 2021
7MGR
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BU of 7mgr by Molmil
SARS-CoV-2 main protease in complex with nsp8/9 substrate peptide
Descriptor: 3C-like proteinase, ALA-VAL-LYS-LEU-GLN-ASN-ASN-GLU
Authors:MacDonald, E.A, Windsor, I.W, Hinshaw, S.M.
Deposit date:2021-04-13
Release date:2021-06-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Recognition of Divergent Viral Substrates by the SARS-CoV-2 Main Protease.
Acs Infect Dis., 7, 2021
5MHQ
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BU of 5mhq by Molmil
CCT068127 in complex with CDK2
Descriptor: (2~{R},3~{S})-3-[[9-propan-2-yl-6-(pyridin-3-ylmethylamino)purin-2-yl]amino]pentan-2-ol, Cyclin-dependent kinase 2
Authors:Whittaker, S.R, Barlow, C, Martin, M.P, Mancusi, C, Wagner, S, Barrie, E, te Poele, R, Sharp, S, Brown, N, Wilson, S, Clarke, P, Walton, M.I, MacDonald, E, Blagg, J, Noble, M.E.M, Garrett, M.D, Workman, P.
Deposit date:2016-11-25
Release date:2017-12-20
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor.
Mol Oncol, 12, 2018

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