3R88
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![BU of 3r88 by Molmil](/molmil-images/mine/3r88) | Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS145) | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-amino-4,5-dimethoxybenzoic acid, Anthranilate phosphoribosyltransferase, ... | 著者 | Castell, A, Short, F.L, Lott, J.S. | 登録日 | 2011-03-23 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52, 2013
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4OWV
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![BU of 4owv by Molmil](/molmil-images/mine/4owv) | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with anthranilate | 分子名称: | 2-AMINOBENZOIC ACID, Anthranilate phosphoribosyltransferase, GLYCEROL, ... | 著者 | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | 登録日 | 2014-02-04 | 公開日 | 2014-04-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461, 2014
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4OWQ
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![BU of 4owq by Molmil](/molmil-images/mine/4owq) | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 3-methylanthranilate, PRPP and Magnesium | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-azanyl-3-methyl-benzoic acid, Anthranilate phosphoribosyltransferase, ... | 著者 | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | 登録日 | 2014-02-03 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461, 2014
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4OWS
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![BU of 4ows by Molmil](/molmil-images/mine/4ows) | Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 4-methylanthranilate, PRPP and Magnesium | 分子名称: | 2-azanyl-4-methyl-benzoic acid, Anthranilate phosphoribosyltransferase, IMIDAZOLE, ... | 著者 | Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. | 登録日 | 2014-02-03 | 公開日 | 2014-04-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461, 2014
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3QQS
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![BU of 3qqs by Molmil](/molmil-images/mine/3qqs) | Anthranilate phosphoribosyltransferase (TRPD) from Mycobacterium tuberculosis (complex with inhibitor ACS172) | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2,2'-iminodibenzoic acid, Anthranilate phosphoribosyltransferase, ... | 著者 | Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2011-02-16 | 公開日 | 2012-08-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52, 2013
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3QR9
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![BU of 3qr9 by Molmil](/molmil-images/mine/3qr9) | |
3QS8
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![BU of 3qs8 by Molmil](/molmil-images/mine/3qs8) | Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS174) | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-benzylbenzoic acid, Anthranilate phosphoribosyltransferase, ... | 著者 | Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2011-02-20 | 公開日 | 2012-08-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52, 2013
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3ST6
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![BU of 3st6 by Molmil](/molmil-images/mine/3st6) | Structure of a M. tuberculosis Synthase, MbtI, in Complex with an Isochorismate Analogue Inhibitor | 分子名称: | 3-[(1-carboxyethenyl)oxy]-2-hydroxybenzoic acid, Isochorismate synthase/isochorismate-pyruvate lyase mbtI | 著者 | Chi, G, Bulloch, E.M.M, Manos-Turvey, A, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2011-07-08 | 公開日 | 2012-05-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis Biochemistry, 51, 2012
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3R6C
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![BU of 3r6c by Molmil](/molmil-images/mine/3r6c) | Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS179) | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 8-methoxyphenanthro[3,4-d][1,3]dioxole-5,6-dicarboxylic acid, Anthranilate phosphoribosyltransferase, ... | 著者 | Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2011-03-21 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52, 2013
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3TWP
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![BU of 3twp by Molmil](/molmil-images/mine/3twp) | Crystal structure of M. tuberculosis TrpD in complex with an inhibitor | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-HYDROXYBENZOIC ACID, Anthranilate phosphoribosyltransferase, ... | 著者 | Castell, A, Short, F.L, Lott, J.S. | 登録日 | 2011-09-22 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52, 2013
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