7R1G
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![BU of 7r1g by Molmil](/molmil-images/mine/7r1g) | Structure of E.coli Class 2 L-asparaginase EcAIII, mutant RDM1-38 (R207C, D210S, S211V) | 分子名称: | Beta-aspartyl-peptidase, Isoaspartyl peptidase, SODIUM ION | 著者 | Loch, J.I, Kadziolka, K, Jaskolski, M. | 登録日 | 2022-02-02 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and biophysical studies of new L-asparaginase variants: lessons from random mutagenesis of the prototypic Escherichia coli Ntn-amidohydrolase. Acta Crystallogr D Struct Biol, 78, 2022
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7QYM
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![BU of 7qym by Molmil](/molmil-images/mine/7qym) | Structure of E.coli Class 2 L-asparaginase EcAIII, mutant RDM1-18 (R207V, D210P, S211W) | 分子名称: | Beta-aspartyl-peptidase, CHLORIDE ION, Isoaspartyl peptidase, ... | 著者 | Loch, J.I, Klonecka, A, Kadziolka, K, Bonarek, P, Barciszewski, J, Imiolczyk, B, Brzezinski, K, Jaskolski, M. | 登録日 | 2022-01-28 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural and biophysical studies of new L-asparaginase variants: lessons from random mutagenesis of the prototypic Escherichia coli Ntn-amidohydrolase. Acta Crystallogr D Struct Biol, 78, 2022
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7QYX
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![BU of 7qyx by Molmil](/molmil-images/mine/7qyx) | Structure of E.coli Class 2 L-asparaginase EcAIII, mutant RDM1-24 (R207A, D210S, S211T) | 分子名称: | Beta-aspartyl-peptidase, CHLORIDE ION, Isoaspartyl peptidase, ... | 著者 | Loch, J.I, Klonecka, A, Kadziolka, K, Bonarek, P, Barciszewski, J, Imiolczyk, B, Brzezinski, K, Jaskolski, M. | 登録日 | 2022-01-29 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural and biophysical studies of new L-asparaginase variants: lessons from random mutagenesis of the prototypic Escherichia coli Ntn-amidohydrolase. Acta Crystallogr D Struct Biol, 78, 2022
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4NLJ
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![BU of 4nlj by Molmil](/molmil-images/mine/4nlj) | Crystal structure of sheep beta-lactoglobulin (space group P1) | 分子名称: | Beta-lactoglobulin-1/B, SULFATE ION | 著者 | Loch, J.I, Molenda, M, Kopec, M, Swiatek, S, Lewinski, K. | 登録日 | 2013-11-14 | 公開日 | 2014-03-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure of two crystal forms of sheep beta-lactoglobulin with EF-loop in closed conformation Biopolymers, 101, 2014
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7OS5
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![BU of 7os5 by Molmil](/molmil-images/mine/7os5) | Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (orthorhombic form OP) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, L-asparaginase, ... | 著者 | Loch, J.I, Imiolczyk, B, Gilski, M, Jaskolski, M. | 登録日 | 2021-06-07 | 公開日 | 2021-11-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.293 Å) | 主引用文献 | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site. Nat Commun, 12, 2021
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7OS6
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![BU of 7os6 by Molmil](/molmil-images/mine/7os6) | Crystal structure of Rhizobium etli inducible L-asparaginase ReAV (monoclinic form MP1) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, ETHANOL, ... | 著者 | Loch, J.I, Imiolczyk, B, Gilski, M, Jaskolski, M. | 登録日 | 2021-06-07 | 公開日 | 2021-11-24 | 最終更新日 | 2023-04-26 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Crystal structures of the elusive Rhizobium etli L-asparaginase reveal a peculiar active site. Nat Commun, 12, 2021
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7Q19
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![BU of 7q19 by Molmil](/molmil-images/mine/7q19) | Beta-lactoglobulin mutant FAW (I56F/L39A/M107W) in complex with desipramine (FAW-DSM#3) | 分子名称: | 1,2-ETHANEDIOL, 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, Beta-lactoglobulin, ... | 著者 | Loch, J.I, Barciszewski, J, Pokrywka, K, Lewinski, K. | 登録日 | 2021-10-18 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | New ligand-binding sites identified in the crystal structures of [beta]-lactoglobulin complexes with desipramine Iucrj, 9, 2022
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7Q2N
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![BU of 7q2n by Molmil](/molmil-images/mine/7q2n) | Beta-lactoglobulin mutant FAF (I56F/L39A/M107F) in complex with desipramine (FAF-DSM) | 分子名称: | 1,2-ETHANEDIOL, 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, Beta-lactoglobulin, ... | 著者 | Loch, J.I, Barciszewski, J, Lewinski, K. | 登録日 | 2021-10-25 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | New ligand-binding sites identified in the crystal structures of [beta]-lactoglobulin complexes with desipramine Iucrj, 9, 2022
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7Q2P
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![BU of 7q2p by Molmil](/molmil-images/mine/7q2p) | Beta-lactoglobulin mutant FAW (I56F/L39A/M107W) in complex with desipramine (FAW-DSM#2) | 分子名称: | 1,2-ETHANEDIOL, 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, Beta-lactoglobulin, ... | 著者 | Loch, J.I, Barciszewski, J, Pokrywka, K, Lewinski, K. | 登録日 | 2021-10-25 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | New ligand-binding sites identified in the crystal structures of [beta]-lactoglobulin complexes with desipramine Iucrj, 9, 2022
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7Q18
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![BU of 7q18 by Molmil](/molmil-images/mine/7q18) | Beta-lactoglobulin mutant FAF (I56F/L39A/M107F), unliganded form | 分子名称: | Beta-lactoglobulin, SULFATE ION | 著者 | Loch, J.I, Cymborowski, M.T, Minor, W, Lewinski, K. | 登録日 | 2021-10-18 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.804 Å) | 主引用文献 | New ligand-binding sites identified in the crystal structures of [beta]-lactoglobulin complexes with desipramine Iucrj, 9, 2022
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7Q17
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![BU of 7q17 by Molmil](/molmil-images/mine/7q17) | Beta-lactoglobulin mutant FAW (I56F/L39A/M107W), unliganded form | 分子名称: | 1,2-ETHANEDIOL, Beta-lactoglobulin | 著者 | Loch, J.I, Barciszewski, J, Lewinski, K. | 登録日 | 2021-10-18 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | New ligand-binding sites identified in the crystal structures of [beta]-lactoglobulin complexes with desipramine Iucrj, 9, 2022
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7Q2O
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![BU of 7q2o by Molmil](/molmil-images/mine/7q2o) | Beta-lactoglobulin mutant FAW (I56F/L39A/M107W) in complex with desipramine (FAW-DSM#1) | 分子名称: | 1,2-ETHANEDIOL, 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, Beta-lactoglobulin, ... | 著者 | Loch, J.I, Barciszewski, J, Lewinski, K. | 登録日 | 2021-10-25 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | New ligand-binding sites identified in the crystal structures of [beta]-lactoglobulin complexes with desipramine Iucrj, 9, 2022
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7BGX
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![BU of 7bgx by Molmil](/molmil-images/mine/7bgx) | Mutant F105L of recombinant beta-lactoglobulin | 分子名称: | Beta-lactoglobulin, GLYCEROL, SULFATE ION | 著者 | Loch, J.I, Wrobel, P, Lewinski, K. | 登録日 | 2021-01-08 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Interactions of new lactoglobulin variants with tetracaine: crystallographic studies of ligand binding to lactoglobulin mutants possessing single substitution in the binding pocket. Acta Biochim.Pol., 68, 2021
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7BF8
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![BU of 7bf8 by Molmil](/molmil-images/mine/7bf8) | |
7BF7
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![BU of 7bf7 by Molmil](/molmil-images/mine/7bf7) | |
7BGA
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![BU of 7bga by Molmil](/molmil-images/mine/7bga) | |
7BGZ
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![BU of 7bgz by Molmil](/molmil-images/mine/7bgz) | Mutant L39K of recombinant beta-lactoglobulin in complex with endogenous ligand | 分子名称: | 1,2-ETHANEDIOL, Beta-lactoglobulin, DECANOIC ACID | 著者 | Loch, J.I, Siuda, M.K, Lewinski, K. | 登録日 | 2021-01-09 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Interactions of new lactoglobulin variants with tetracaine: crystallographic studies of ligand binding to lactoglobulin mutants possessing single substitution in the binding pocket. Acta Biochim.Pol., 68, 2021
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7BF9
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![BU of 7bf9 by Molmil](/molmil-images/mine/7bf9) | |
7BH0
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![BU of 7bh0 by Molmil](/molmil-images/mine/7bh0) | |
8C0I
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![BU of 8c0i by Molmil](/molmil-images/mine/8c0i) | Structure of E. coli Class 2 L-asparaginase EcAIII, mutant M200L (acyl-enzyme intermediate) | 分子名称: | CHLORIDE ION, Isoaspartyl peptidase subunit alpha, Isoaspartyl peptidase subunit beta, ... | 著者 | Sciuk, A, Jaskolski, M, Loch, J.I. | 登録日 | 2022-12-16 | 公開日 | 2023-05-03 | 最終更新日 | 2023-06-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The effects of nature-inspired amino acid substitutions on structural and biochemical properties of the E. coli L-asparaginase EcAIII. Protein Sci., 32, 2023
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8C23
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![BU of 8c23 by Molmil](/molmil-images/mine/8c23) | Structure of E. coli Class 2 L-asparaginase EcAIII, mutant M200T (monoclinic form M200T#m) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Sciuk, A, Ruszkowski, M, Jaskolski, M, Loch, J.I. | 登録日 | 2022-12-21 | 公開日 | 2023-05-03 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.842 Å) | 主引用文献 | The effects of nature-inspired amino acid substitutions on structural and biochemical properties of the E. coli L-asparaginase EcAIII. Protein Sci., 32, 2023
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8RUF
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![BU of 8ruf by Molmil](/molmil-images/mine/8ruf) | Crystal structure of Rhizobium etli L-asparaginase ReAV D187A mutant | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | 著者 | Pokrywka, K, Grzechowiak, M, Sliwiak, J, Worsztynowicz, P, Loch, J.I, Ruszkowski, M, Gilski, M, Jaskolski, M. | 登録日 | 2024-01-30 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV. Front Chem, 12, 2024
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8RUA
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![BU of 8rua by Molmil](/molmil-images/mine/8rua) | Crystal structure of Rhizobium etli L-asparaginase ReAV C135A mutant | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | 著者 | Pokrywka, K, Grzechowiak, M, Sliwiak, J, Worsztynowicz, P, Loch, J.I, Ruszkowski, M, Gilski, M, Jaskolski, M. | 登録日 | 2024-01-30 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV. Front Chem, 12, 2024
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8RUD
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![BU of 8rud by Molmil](/molmil-images/mine/8rud) | Crystal structure of Rhizobium etli L-asparaginase ReAV K138A mutant | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Pokrywka, K, Grzechowiak, M, Sliwiak, J, Worsztynowicz, P, Loch, J.I, Ruszkowski, M, Gilski, M, Jaskolski, M. | 登録日 | 2024-01-30 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV. Front Chem, 12, 2024
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8RUG
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![BU of 8rug by Molmil](/molmil-images/mine/8rug) | Crystal structure of Rhizobium etli L-asparaginase ReAV C189A mutant | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Pokrywka, K, Grzechowiak, M, Sliwiak, J, Worsztynowicz, P, Loch, J.I, Ruszkowski, M, Gilski, M, Jaskolski, M. | 登録日 | 2024-01-30 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Probing the active site of Class 3 L-asparaginase by mutagenesis. I. Tinkering with the zinc coordination site of ReAV. Front Chem, 12, 2024
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