7B0M
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![BU of 7b0m by Molmil](/molmil-images/mine/7b0m) | Sugar transaminase from a metagenome collected from troll oil field production water | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Sugar aminotransferase, ... | Authors: | Littlechild, J.A, De Rose, S.A, Isupov, M.N, Sayer, C, Karki, S. | Deposit date: | 2020-11-20 | Release date: | 2021-12-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Sugar transaminases from hot environments To Be Published
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2VXI
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![BU of 2vxi by Molmil](/molmil-images/mine/2vxi) | The binding of heme and zinc in Escherichia coli Bacterioferritin | Descriptor: | BACTERIOFERRITIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | Authors: | Willies, S.C, Isupov, M.N, Garman, E.F, Littlechild, J.A. | Deposit date: | 2008-07-04 | Release date: | 2008-11-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | The Binding of Haem and Zinc in the 1.9 A X-Ray Structure of Escherichia Coli Bacterioferritin. J.Biol.Inorg.Chem., 14, 2009
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2ALD
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![BU of 2ald by Molmil](/molmil-images/mine/2ald) | HUMAN MUSCLE ALDOLASE | Descriptor: | FRUCTOSE-BISPHOSPHATE ALDOLASE | Authors: | Dalby, A.R, Littlechild, J.A. | Deposit date: | 1998-10-21 | Release date: | 1999-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications. Protein Sci., 8, 1999
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7NZO
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![BU of 7nzo by Molmil](/molmil-images/mine/7nzo) | D-lyxose isomerasefrom the hyperthermophilic archaeon Thermofilum sp | Descriptor: | 1,2-ETHANEDIOL, D-lyxose/D-mannose family sugar isomerase, MANGANESE (II) ION | Authors: | De Rose, S.A, Isupov, M.N, Littlechild, J.A, Schoenheit, P. | Deposit date: | 2021-03-24 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Biochemical and Structural Characterisation of a Novel D-Lyxose Isomerase From the Hyperthermophilic Archaeon Thermofilum sp. Front Bioeng Biotechnol, 9, 2021
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7NZP
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![BU of 7nzp by Molmil](/molmil-images/mine/7nzp) | D-lyxose isomerase from the hyperthermophilic archaeon Thermofilum sp complexed with D-fructose | Descriptor: | 1,2-ETHANEDIOL, D-lyxose/D-mannose family sugar isomerase, MANGANESE (II) ION, ... | Authors: | De Rose, S.A, Isupov, M.N, Littlechild, J.A, Schoenheit, P. | Deposit date: | 2021-03-24 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.345 Å) | Cite: | Biochemical and Structural Characterisation of a Novel D-Lyxose Isomerase From the Hyperthermophilic Archaeon Thermofilum sp. Front Bioeng Biotechnol, 9, 2021
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4UWM
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![BU of 4uwm by Molmil](/molmil-images/mine/4uwm) | Type II Baeyer-Villiger monooxygenase.The oxygenating constituent of 3,6-diketocamphane monooxygenase from CAM plasmid of Pseudomonas putida in complex with FMN. | Descriptor: | 3,6-DIKETOCAMPHANE 1,6 MONOOXYGENASE, DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, ... | Authors: | Isupov, M.N, Schroeder, E, Gibson, R.P, Beecher, J, Donadio, G, Saneei, V, Dcunha, S, McGhie, E.J, Sayer, C, Davenport, C.F, Lau, P.C, Hasegawa, Y, Iwaki, H, Kadow, M, Loschinski, K, Bornscheuer, U.T, Bourenkov, G, Littlechild, J.A. | Deposit date: | 2014-08-12 | Release date: | 2015-08-26 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Oxygenating Constituent of 3,6-Diketocamphane Monooxygenase from the Cam Plasmid of Pseudomonas Putida: The First Crystal Structure of a Type II Baeyer-Villiger Monooxygenase. Acta Crystallogr.,Sect.D, 71, 2015
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2VIM
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![BU of 2vim by Molmil](/molmil-images/mine/2vim) | X-ray structure of Fasciola hepatica thioredoxin | Descriptor: | THIOREDOXIN | Authors: | Line, K, Isupov, M.N, Garcia-Rodriguez, E, Maggioli, G, Parra, F, Littlechild, J.A. | Deposit date: | 2007-12-05 | Release date: | 2008-07-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | The Fasciola Hepatica Thioredoxin: High Resolution Structure Reveals Two Oxidation States. Mol.Biochem.Parasitol., 161, 2008
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7B0D
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![BU of 7b0d by Molmil](/molmil-images/mine/7b0d) | Sugar transaminase from Archaeoglobus veneficus | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | Authors: | James, P, Littlechild, J.A, De Rose, S.A, Isupov, M.N. | Deposit date: | 2020-11-19 | Release date: | 2021-12-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Sugar transaminases from hot environments To Be Published
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7NZQ
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![BU of 7nzq by Molmil](/molmil-images/mine/7nzq) | D-lyxose isomerase from the hyperthermophilic archaeon Thermofilum sp complexed with D-mannose | Descriptor: | 1,2-ETHANEDIOL, D-lyxose/D-mannose family sugar isomerase, DI(HYDROXYETHYL)ETHER, ... | Authors: | De Rose, S.A, Isupov, M.N, Littlechild, J.A, Schoenheit, P. | Deposit date: | 2021-03-24 | Release date: | 2021-10-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Biochemical and Structural Characterisation of a Novel D-Lyxose Isomerase From the Hyperthermophilic Archaeon Thermofilum sp. Front Bioeng Biotechnol, 9, 2021
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6YAK
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![BU of 6yak by Molmil](/molmil-images/mine/6yak) | Split gene transketolase, active alpha2beta2 heterotetramer | Descriptor: | (2S)-2-hydroxybutanedioic acid, 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-2H-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, C-terminal component of the split chain transketolase, ... | Authors: | Isupov, M.N, Littlechild, J.A, James, P. | Deposit date: | 2020-03-12 | Release date: | 2020-11-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | A 'Split-Gene' Transketolase From the Hyper-Thermophilic Bacterium Carboxydothermus hydrogenoformans : Structure and Biochemical Characterization. Front Microbiol, 11, 2020
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6YAJ
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![BU of 6yaj by Molmil](/molmil-images/mine/6yaj) | Split gene transketolase, inactive beta4 tetramer | Descriptor: | 1,2-ETHANEDIOL, C-terminal chain of split transketolase from Carboxydothermus hydrogenoformans, DI(HYDROXYETHYL)ETHER, ... | Authors: | Isupov, M.N, Littlechild, J.A, James, P. | Deposit date: | 2020-03-12 | Release date: | 2020-11-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A 'Split-Gene' Transketolase From the Hyper-Thermophilic Bacterium Carboxydothermus hydrogenoformans : Structure and Biochemical Characterization. Front Microbiol, 11, 2020
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5NG7
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![BU of 5ng7 by Molmil](/molmil-images/mine/5ng7) | Novel epoxide hydrolases belonging to the alpha/beta hydrolases superfamily in metagenomes from hot environments | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Ferrandi, E.E, De Rose, S.A, Sayer, C, Guazzelli, E, Marchesi, C, Saneei, V, Isupov, M.N, Littlechild, J.A, Monti, D. | Deposit date: | 2017-03-17 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | New Thermophilic alpha / beta Class Epoxide Hydrolases Found in Metagenomes From Hot Environments. Front Bioeng Biotechnol, 6, 2018
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1UP8
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![BU of 1up8 by Molmil](/molmil-images/mine/1up8) | Recombinant vanadium-dependent bromoperoxidase from red algae Corallina pilulifera | Descriptor: | CALCIUM ION, PHOSPHATE ION, VANADIUM-DEPENDENT BROMOPEROXIDASE 1 | Authors: | Garcia-Rodriguez, E, Isupov, M, Ohshiro, T, Izumi, Y, Littlechild, J.A. | Deposit date: | 2003-09-29 | Release date: | 2003-09-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Enhancing Effect of Calcium and Vanadium Ions on Thermal Stability of Bromoperoxidase from Corallina Pilulifera. J.Biol.Inorg.Chem., 10, 2005
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8PAJ
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![BU of 8paj by Molmil](/molmil-images/mine/8paj) | Crystal Structure of a Squalene-Hopene cyclase from Archangium gephyra | Descriptor: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | Authors: | Worthy, H.L, Isupov, M.N, Littlechild, J.A, Mitchell, D.E. | Deposit date: | 2023-06-08 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structure of a mesophilic Squalene-Hopene Cyclases from Cystobacter fuscus and Archangium gephyra To Be Published
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8PAK
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![BU of 8pak by Molmil](/molmil-images/mine/8pak) | Crystal Structure of a Squalene-Hopene Cyclase from Cystobacter fuscus | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ... | Authors: | Worthy, H.L, Mitchell, D.E, Isupov, M.N, Littlechild, J.A. | Deposit date: | 2023-06-08 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structure of Mesophilic Squalene-Hopene Cyclases from Cystobacter fuscus and Archangium gephyra To Be Published
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8AGS
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![BU of 8ags by Molmil](/molmil-images/mine/8ags) | Cyclohexane epoxide soak of epoxide hydrolase from metagenomic source ch65 resulting in halogenated compound in the active site | Descriptor: | 1,2-ETHANEDIOL, 2-CHLOROPHENOL, Alpha/beta epoxide hydrolase, ... | Authors: | Isupov, M.N, De Rose, S.A, Mitchell, D, Littlechild, J.A. | Deposit date: | 2022-07-20 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Complexes of epoxide hydrolase from metagenomic source ch65 To Be Published
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8AGN
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![BU of 8agn by Molmil](/molmil-images/mine/8agn) | Cyclohexane epoxide low pH soak of epoxide hydrolase from metagenomic source ch65 | Descriptor: | (1R,6S)-7-oxabicyclo[4.1.0]heptane, 1,2-ETHANEDIOL, Alpha/beta epoxide hydrolase, ... | Authors: | Isupov, M.N, De Rose, S.A, Mitchell, D, Littlechild, J.A. | Deposit date: | 2022-07-20 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.957 Å) | Cite: | Complexes of epoxide hydrolase from metagenomic source ch65 To Be Published
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8AGP
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![BU of 8agp by Molmil](/molmil-images/mine/8agp) | Halogenated product of limonene epoxide turnover by epoxide hydrolase from metagenomic source ch65 | Descriptor: | (1~{S},2~{S},4~{R})-2-chloranyl-1-methyl-4-prop-1-en-2-yl-cyclohexan-1-ol, 1,2-ETHANEDIOL, Alpha/beta epoxide hydrolase, ... | Authors: | Isupov, M.N, De Rose, S.A, Mitchell, D, Littlechild, J.A. | Deposit date: | 2022-07-20 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Complexes of epoxide hydrolase from metagenomic source ch65 To Be Published
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8AGM
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![BU of 8agm by Molmil](/molmil-images/mine/8agm) | Limonene epoxide low pH soak of epoxide hydrolase from metagenomic source ch65 | Descriptor: | 1,2-ETHANEDIOL, Alpha/beta epoxide hydrolase, CHLORIDE ION, ... | Authors: | Isupov, M.N, De Rose, S.A, Mitchell, D, Littlechild, J.A. | Deposit date: | 2022-07-20 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.966 Å) | Cite: | Complexes of epoxide hydrolase from metagenomic source ch65 To Be Published
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3HGJ
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![BU of 3hgj by Molmil](/molmil-images/mine/3hgj) | Old Yellow Enzyme from Thermus scotoductus SA-01 complexed with p-hydroxy-benzaldehyde | Descriptor: | Chromate reductase, FLAVIN MONONUCLEOTIDE, P-HYDROXYBENZALDEHYDE | Authors: | Opperman, D.J, Sewell, B.T, Litthauer, D, Isupov, M.N, Littlechild, J.A, van Heerden, E. | Deposit date: | 2009-05-14 | Release date: | 2010-02-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a thermostable old yellow enzyme from Thermus scotoductus SA-01 Biochem.Biophys.Res.Commun., 393, 2010
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1H2B
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![BU of 1h2b by Molmil](/molmil-images/mine/1h2b) | Crystal Structure of the Alcohol Dehydrogenase from the Hyperthermophilic Archaeon Aeropyrum pernix at 1.65A Resolution | Descriptor: | ALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), OCTANOIC ACID (CAPRYLIC ACID), ... | Authors: | Guy, J.E, Isupov, M.N, Littlechild, J.A. | Deposit date: | 2002-08-02 | Release date: | 2003-08-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The structure of an alcohol dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. J.Mol.Biol., 331, 2003
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5FRD
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![BU of 5frd by Molmil](/molmil-images/mine/5frd) | Structure of a thermophilic esterase | Descriptor: | CARBOXYLESTERASE (EST-2), CHLORIDE ION, CITRATE ANION, ... | Authors: | Sayer, C, Finnigan, W, Isupov, M.N, Levisson, M, Kengen, S.W.M, van der Oost, J, Harmer, N, Littlechild, J.A. | Deposit date: | 2015-12-17 | Release date: | 2016-05-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural and Biochemical Characterisation of Archaeoglobus Fulgidus Esterase Reveals a Bound Coa Molecule in the Vicinity of the Active Site. Sci.Rep., 6, 2016
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3HF3
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![BU of 3hf3 by Molmil](/molmil-images/mine/3hf3) | Old Yellow Enzyme from Thermus scotoductus SA-01 | Descriptor: | Chromate reductase, FLAVIN MONONUCLEOTIDE, SULFATE ION | Authors: | Opperman, D.J, Sewell, B.T, Litthauer, D, Isupov, M.N, Littlechild, J.A, van Heerden, E. | Deposit date: | 2009-05-11 | Release date: | 2010-02-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a thermostable old yellow enzyme from Thermus scotoductus SA-01 Biochem.Biophys.Res.Commun., 393, 2010
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5MR0
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![BU of 5mr0 by Molmil](/molmil-images/mine/5mr0) | Thermophilic archaeal branched-chain amino acid transaminases from Geoglobus acetivorans and Archaeoglobus fulgidus: biochemical and structural characterisation | Descriptor: | 1,2-ETHANEDIOL, 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, CHLORIDE ION, ... | Authors: | Isupov, M.N, Littlechild, J.A, James, P, Sayer, C, Sutter, J.M, Schmidt, M, Schoenheit, P. | Deposit date: | 2016-12-21 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Thermostable Branched-Chain Amino Acid Transaminases From the ArchaeaGeoglobus acetivoransandArchaeoglobus fulgidus: Biochemical and Structural Characterization. Front Bioeng Biotechnol, 7, 2019
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5MQZ
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![BU of 5mqz by Molmil](/molmil-images/mine/5mqz) | Archaeal branched-chain amino acid aminotransferase from Archaeoglobus fulgidus; holoform | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | James, P, Isupov, M.N, Sayer, C, Littlechild, J.A, Sutter, J.M, Schmidt, M, Schoenheit, P. | Deposit date: | 2016-12-21 | Release date: | 2018-01-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Thermostable Branched-Chain Amino Acid Transaminases From the Archaea Geoglobus acetivorans and Archaeoglobus fulgidus : Biochemical and Structural Characterization. Front Bioeng Biotechnol, 7, 2019
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